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Srivastava Lab at UCLA @_SrivastavaLab

Electrostatic Self-assembly | Polymer Upcycling | Department of Chemical & Biomolecular Engineering at UCLA | PI: @samanvaya

Joined May 2023
  • Tweets 54
  • Following 283
  • Followers 227
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We are cxcited to represent UCLA Chemical & Biomolecular Engineering at the #APS2025 Global Physical Summit @APSPhysics! šŸš€ Our group will present 9 talks 4 posters showcasing our latest research. Check out our lineup, and we hope to connect with you there!
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Our latest publication in @ChemCommun , led by @FahedAlbreiki , introduces a modular synthesis of catechol-containing triblock copolymers that form strong and wet adhesives! pubs.rsc.org/en/content/artiā€¦ ā€Ø @UclaCBE @UCLAengineering @UCLA #NSFfunded #MusselAdhesion #Hydrogels

Modular synthesis and facile network formation of catechol functionalized triblock copolymers

We report the synthesis of catechol-functionalized symmetric triblock polymers comprising densely functionalized catechol endblocks using anionic ring-opening polymerization (AROP) and thiolā€“ene...

pubs.rsc.org
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In this work, we utilize ring opening polymerization and thiol-ene click chemistry to produce triblock polycatechol (tbPC) - polymers that feature high density of catechol endblocks bridged with a hydrophilic PEG middle block.
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The result? Cross-linkable polymers that gel rapidly and achieve robust adhesion across diverse surfaces - marking a stark enhancement in properties compared to conventional catechol-based wet adhesives. Dive into the full details of our work here:Ā pubs.rsc.org/en/content/artiā€¦
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Excited and proud of Advait Holkar, a graduate of our lab, who has been selected as an Activate Fellow! He is launching Prāio Inc., which will focus on enabling low-cost production of sustainable aviation fuel (SAF) through a pioneering protocellular biocatalysis platform (1/2)
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Advait developed this innovative technology in his graduate research. Join us in supporting this solution to reduce CO2 emissions and drive sustainable aviation! šŸŒāœˆļø activate.org/praio #TechInnovation #SustainableAviation #Praio #uclasamueli #ucla #activate (2/2)

Praio

Praio will economically manufacture bio-derived commodity chemicals, such as aviation fuel, using synthetic protocells with a reduced carbon footprint.

activate.org
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Srivastava Lab at UCLA retweeted
BioPACIFIC MIP@BioPACIFICMIP
23 May 2024
šŸš€ The latest study from @samanvaya's group shows that comb polyelectrolyte stabilizers improve coacervate microdroplet stability for drug delivery. Thanks to @BioPACIFICMIP, high-throughput materials characterization was possible. bit.ly/4dRUoSM @softmatter @cnsiatucla
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Our work on using quantitative turbidimetry for characterizing stabilized complex coacervate dispersions using automation is out in @softmatter pubs.rsc.org/en/content/artiā€¦ @UclaCBE @BioPACIFICMIP @cnsiatucla @UCLAengineering @UCLAnewsroom @samanvaya @ShangGaoCBE (1/6)

Quantitative turbidimetric characterization of stabilized complex coacervate dispersions

Stabilizing complex coacervate microdroplets is desirable due to their various applications, such as bioreactors, drug delivery vehicles, and encapsulants. Here, we present quantitative characteriz...

pubs.rsc.org
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Number density and avg. microdroplet size are shown to be controlled by varying the cPE and salt concentrations. Turbidity maps, akin to binodal phase maps, depict an expansion of the turbid two-phase region. (5/6)
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An increase in the salt resistance of the coacervates upon introduction of cPEs is seen to be maintained over 15 days, underlining the role of cPEs in imparting and maintaining stability over extended durations. (6/6)
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Our group members spent a fun afternoon at the Willows Community Schoolā€™s Sunday Funday with 100 kids excited to learn about polymers, surface tension and complex fluids!
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Srivastava Lab at UCLA retweeted
BioPACIFIC MIP@BioPACIFICMIP
27 Mar 2024
šŸ”¬ The latest paper from @BioPACIFICMIP researchers @FahedAlbreiki and @samanvaya from @UCLA in collaboration with project scientist Juan Manuel Uruena reveals how block polyelectrolyte additives enhance #3Dprinting of biopolymer inks. Read it here: pubs.acs.org/doi/10.1021/acsā€¦

Block Polyelectrolyte Additives That Modulate the Viscoelasticity and Enhance the Printability of...

We demonstrate the utility of block polyelectrolyte (bPE) additives to enhance viscosity and resolve challenges with the three-dimensional (3D) printability of extrusion-based biopolymer inks. The...

pubs.acs.org
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Srivastava Lab at UCLA retweeted
Srivastava Lab at UCLA@_SrivastavaLab
22 Feb 2024
Our work on enabling 3D printability of gelatin inks in physiological conditions by utilising self-assembled block polyelectrolytes scaffolds is out: pubs.acs.org/doi/10.1021/acsā€¦ Congrats to Tobias, @FahedAlbreiki, @DefuLi8 & Alisa! @samanvaya @UclaCBE @BioPACIFICMIP @ACSPublications

Block Polyelectrolyte Additives That Modulate the Viscoelasticity and Enhance the Printability of...

We demonstrate the utility of block polyelectrolyte (bPE) additives to enhance viscosity and resolve challenges with the three-dimensional (3D) printability of extrusion-based biopolymer inks. The...

pubs.acs.org
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Our work on enabling 3D printability of gelatin inks in physiological conditions by utilising self-assembled block polyelectrolytes scaffolds is out: pubs.acs.org/doi/10.1021/acsā€¦ Congrats to Tobias, @FahedAlbreiki, @DefuLi8 & Alisa! @samanvaya @UclaCBE @BioPACIFICMIP @ACSPublications

Block Polyelectrolyte Additives That Modulate the Viscoelasticity and Enhance the Printability of...

We demonstrate the utility of block polyelectrolyte (bPE) additives to enhance viscosity and resolve challenges with the three-dimensional (3D) printability of extrusion-based biopolymer inks. The...

pubs.acs.org
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We developed inks comprising gelatin and block polyelectrolyte scaffolds that were printable at physiological temperatures in commercial extrusion-based printers w/ high resolution (<0.5 mm).
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We provide insights about their viscoelastic properties and 3D printability assessments. Thanks to our collaborators at @KITKarlsruhe and @BioPACIFICMIP for their valuable contributions! @UclaCBE @UCLAengineering
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