#researcher Interested in Bioinformatics | Cancer genomics | Clonal hematopoiesis

Joined May 2010
2 Photos and videos
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Excited to be part of the Data-Driven Life Science (DDLS) program and start a lab at University of Gothenburg SciLifeLab We are #recruiting bioinformatic #phdstudents & #postdocs in data-driven cancer genomic projects. lnkd.in/gkkGKdDr
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Abhishek Niroula retweeted
❗️Postdoc opportunity in Human Systems Immunology at Lund University, Sweden (please RT) We are looking for a curious and driven candidate interested in * Human systems immunology * Multiomics methods * Sex differences in immunity Thread below about the position:
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Delighted to contribute to this tour de force by A. Lin @UCSFCardiology, A. Bapat @MGHHeartHealth, @patrick_ellinor @MGHHeartHealth @broadinstitute, & B. Ebert @DanaFarber @broadinstitute using human genetics, murine models, & cell-based models to connect TET2 clonal hematopoiesis with atrial fibrillation ahajournals.org/doi/10.1161/… @CircAHA
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Abhishek Niroula retweeted
The Sjöberg Prize 2024 is awarded to Catherine J. Wu 🌟 Catherine J. Wu, of the Dana-Farber Cancer Institute in Boston, USA, is a pioneer in research that may result in the development of personalised vaccines to treat cancer. She is now awarded the Sjöberg Prize, worth one million US dollars, "for discoveries concerning tumour neoantigens and the immune response to tumour cells as a basis for cancer vaccine development.” @DanaFarber @harvardmed @broadinstitute #sjöbergprize
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Research in @NEJMEvidence by Lachelle Weeks, MD, PhD, (@Lachelle_Dawn) and @DanaFarber led to the development of CHRS, a clinical tool to assess the risk of progression in patients with clonal hematopoiesis (CH), a common precursor to myeloid malignancies. ms.spr.ly/6011gPpCh
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Abhishek Niroula retweeted
It’s finally here! 🥹 evidence.nejm.org/doi/full/1… Thanks to my collaborators @abhinrl @LuskinMarlise @ColemanLindsley @c_j_gibson @jaiswalmdphd @AlexBickMDPhD @pnatarajanmd @DrFlashHeart Luca Malcovati, Donna Neuberg, Waihay Wong, Rich Stone, Dan DeAngelo and of course Ben Ebert
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Out in @Nature today, we describe a new method "PACER" to estimate clonal expansion rate and use it to identify that aberrant TCL1A activation as a cause of #CHIP expansion and potential therapeutic target @J__Stock @Jk_Gopakumar @jaiswalmdphd nature.com/articles/s41586-0…
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We have a vacancy for a computational postdoc in our new data-driven life science (DDLS) funded research group at Sahlgrenska Academy, University of Gothenburg. The candidate will work on genomic study of clonal hematopoiesis and…lnkd.in/eeSw5qiZ lnkd.in/eVNtdpCk
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Abhishek Niroula retweeted
27 Aug 2022
NIH peer review system is far from perfect, but it's the best I've seen. I just "retired" from the GCAT study section after 4 years' of service, which prompted me to share a few thoughts re computational proposals. These are the points that I also remind myself. Other thoughts?🧵
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Abhishek Niroula retweeted
Delighted to share our recent study @BloodJournal from the Ebert Laboratory @DanaFarber linking #ClonalHematopoiesis (CH) and #Gout: doi.org/10.1182/blood.202201… Truly wonderful, collaborative effort across disciplines and geographies!
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Abhishek Niroula retweeted
Our study led by @MGLevin @PennCardiology & @NakaoTetsushi @broadinstitute uses Mendelian randomization to show how tobacco smoking differentially influences the fitness of different mutations linked to clonal hematopoiesis rdcu.be/cMD2Q @SciReports
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Abhishek Niroula retweeted
20 Apr 2022
As a scientist and an illustrator having our article featured on the cover of @Nature is a dream come true I've done an illustrated tweetorial, so this is the illustrators' tweetorial.
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Abhishek Niroula retweeted
Our recent preprint is out now. Here we demonstrate that targeting cohesin subunit STAG1 selectively eliminates leukemic cells harboring STAG2 mutations.
Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations biorxiv.org/cgi/content/shor… #bioRxiv
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Abhishek Niroula retweeted
1/ Thrilled to share our work in this year's @CircAHA #GoRedforWomen issue Beyond predilection to chronic HTN, mechanisms linking preeclampsia/🤰HTN to later-life 🫀 aging/disease are incompletely understood. Can we learn something from the eyes 👀? ahajournals.org/doi/10.1161/…
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Abhishek Niroula retweeted
The Broad Institute is a non-profit research organization that brings scientists from around the world together to solve important problems and propel the understanding and treatment of disease. Hear our researchers share what makes the Broad special: youtu.be/pw0VV5WBZbQ
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Abhishek Niroula retweeted
25 Jan 2022
Seven technologies set to shake up science in 2022 go.nature.com/3FZBC9P

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Our preprint led by @waihaywong @connoremdin & with B. Ebert showing that clonal hematopoiesis is an important (~2-fold risk!) risk factor for chronic liver disease, using complementary data types & experiments in humans & mice. medrxiv.org/content/10.1101/… @medrxivpreprint
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