Microbiology lab at @CAMBUPenn. We study gut-microbiota interactions in the context of infectious disease. Recruiting at all levels! Student-run account.

Joined July 2019
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20 May 2025
So happy to congratulate Dr. Kevin Mears, who defended his thesis yesterday! Kevin received an NIH-NIAID F31 fellowship and had a 1st author publication in Cell Reports ( sciencedirect.com/science/ar… )during his time in lab
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13 Jan 2025
The Abt lab has a Research Technician position opening this Summer. We are seeking an energetic graduating senior interested in immunity and microbiome research. Applicants can go to Careers @ Penn (JR00101259) to find out more!
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2 May 2024
Monoclonal antibody-mediated neutralization of Clostridioides difficil... sciencedirect.com/science/ar…

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2 May 2024
Happy to share this pre-print from out lab. This work was lead by Dr. Joshua Denny, a very talented postdoc, in collaboration with Linda Lieberman from Merck Discovery Immunology
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2 May 2024
By neutralizing toxin and assessing the innate immune response to C diff infection we shed more light on protective vs pathogenic inflammatory host responses.
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Abt Lab retweeted
Prokaryotic Seminar 🦠 next Monday! 2/6/2024 From 4-5 PM at 209 Johnson Pavilion, join Subham Mridha, PhD from the @abt_lab!
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27 Sep 2023
Congratulations to DR. @Emily_Cribas for defending her thesis today. Emily was the first student to join the lab and took a chance with a young PI. So happy for her.
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31 May 2023
Congratulations Dr. @YingYang0204! , who defended her thesis earlier today and gave a beautiful talk on development of Th17 memory in the lung.
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Abt Lab retweeted
Ever wonder what would happen to your immune system if you were stuck with a baby's microbiome? To find out see our new publication in Cell Host and Microbe! authors.elsevier.com/a/1gqSm…

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Super excited to share my and Xinyun Zhang's work published in @MucosalImmunol. We found bacteria-specific memory Th17 cells were still protective even in the context of influenza virus infection. Thank you @abt_lab for all your support! doi.org/10.1016/j.mucimm.202…

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27 Jan 2023
Congratulations to Katelyn Bustin and @MegaMatthewsLab on their paper in @FrontPharmacol. It was great to be part of this project and learn some cool chemistry!
Big congratulations to our PhD student Katelyn Bustin, whose work was published on @FrontPharmacol. Check out this paper about our amazing hydrazine probes for characterizing metabolic drivers of Clostridioides difficile infection! frontiersin.org/articles/10.…
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23 Jan 2023
The Abt lab has a Research Technician position opening this Summer. We are seeking an energetic graduating senior interested in immunity and microbiome research. Applicants can go to Careers @ Penn (JR00066297) to find out more!
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Abt Lab retweeted
New Research: Immunological consequences of microbiome-based therapeutics: The complex network of microscopic organisms living on and within humans, collectively referred to as the microbiome, produce wide array of biologically active… frontiersin.org/articles/10.… #immunology

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16 Nov 2022
Thrilled to share my work from the @joeyzacks lab published today in @nature. We find that enterococci enhance C. difficile fitness and virulence by remodeling the metabolic environment in the gut. Thread below with highlights. nature.com/articles/s41586-0…

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18 Nov 2022
Check out this fantastic work from the Zackular lab! Congrats @joeyzacks and @brokaryote!
Really excited to share our labs first paper published today in @Nature. This work was led by the amazingly talented @Brokaryote, who found that enterococci enhance C. diff fitness and pathogenesis by metabolically remodeling the gut during infection. nature.com/articles/s41586-0…
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Abt Lab retweeted
If someone from #PennIGGRetreat needs a proof of attendance… assuming that Day 2 afternoon hike led by @abt_lab counts… @IGGPenn @simplyseble et al (tag yourself in comments) @SkytopLodge
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