It is despicable that the Covid vaccine manufacturers are going to charge more than $110/dose for the new XBB.1.5 boosters when available in mid-September.
The US government previously paid ~$25/dose, supplied free of charge, and subsidized these companies with untold $ billions.
USC All-American Bronny James collapsed on the court Monday and had a cardiac arrest. He was taken to the hospital and is now in stable condition and no longer in the ICU. Statement:
✳️Colorectal cancer is now the leading cause of cancer related death among males aged 20-39 and 40-49 ‼️It was third among 20-39 age group last year.
✳️ Concerning trend is also seen in young women; CRC related death and will likely surpass breast cancer in near future @OncoAlert
For me, Twitter is for science and I mostly avoid politics. But the moment my country turned into a christian "caliphate", where a minority of extreme angry white males are able to take over women's fundamental rights, is a moment I can not stay silent. I fear for the future!
Important lesson from many recent studies in advanced breast cancer: we need to keep focus on OS benefit. CDK4/6 inhibitors, sacituzumab, pembrolizumab, trastuz deruxtecan all show OS benefits. Barring major gains in QoL or tolerability, OS should be the standard @FDAOncology
T-Dxd in Her2low
A game changer indeed
#asco22#bcsm@OncoAlert#nejm#breastcancer
DB-04 :T-DXd vs TPC in met HER2 1 or 2 (-Fish)
PFS for HR -10.1 mo vs 5.4 mo (HR 0.51); ITT: 9.9mo vs 5.1 mo (HR 0.50)
TNBC 8.5 mo vs 2.9mo (HR 0.46)
OS HR 23.9 mo vs 17.5 mo (HR 0.64)