How are cell-cell interactions governing successful metastatic colonization in the liver? Have a look at our new paper in @nature that introduces an in vivo proximity screen to functionally test cellular interactions in a high-throughput manner. nature.com/articles/s41586-0… 🧵
Running AI agents has become easy. Observing them is the hard part.
Let one run 24/7 for days and your terminal becomes a wall of scrollback no human can ever read. We don't know what it actually did, where it stalled, or whether it quietly went off the rails.
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New paper! How do RNAs "know" where to go inside a cell? We dug into the sequence elements that route RNAs to the right place. It turns out that, in mammals, they're surprisingly massive (>200 nt), multipartite, and wonderfully complicated. 🧵
🤩 spatial panoramic in vivo CRISPR screen via Perturb-DBiT 🤩 Excited to share our collaborative work with @sidichen lab and many outstanding collaborators, now published in Nature Biotechnology!
nature.com/articles/s41587-0…
🚨 Today in @Nature, we report GEMINI—a genetically encoded intracellular memory device that writes cellular dynamics into tree-ring-like fluorescent patterns within cytoplasmic protein assemblies.[1/n]
nature.com/articles/s41586-0…
My postdoc paper has been published! I would like to thank Andreas, Erkin, Vatsi, Farah, and all other members in Moor lab for their invaluable contributions. We conducted a localized RNA mapping study at the subcellular level
🚨Job alert 🚨We are recruiting a Research Technician, primarily with skills in molecular and cellular biology. Come join us in Basel, Switzerland! More info at: jobs.ethz.ch/job/view/JOPG_e…
Simulating Organogenesis in #COMSOL: Tissue Patterning with Directed Cell Migration
👉 detailed walkthrough of how to implement #DCM partial integro-differential equation models
👉 accessible simulations of tissue patterning and morphogenesis.
arxiv.org/pdf/2509.08930
Happy to share our new preprint: Subcellular mRNA localization patterns across tissues resolved with spatial transcriptomics: biorxiv.org/content/10.1101/…
We utilize VisiumHD to extract intra-cellular mRNA polarization patterns in epithelial tissues.
My lab at ETHZ in Basel has an opening for a postdoc in spatial risk stratification: jobs.ethz.ch/job/view/JOPG_e…. Please apply if suitable or RT, thanks!
My lab at ETH has an opening for a Scientist in Antibody & Nanobody Drug Discovery (workspace in Basel, Switzerland): jobs.ethz.ch/job/view/JOPG_e… Please apply if suitable or RT, thanks!
My lab is moving to @ETH_en@ETH_BSSE in Feb 2025! I am very excited for the new start :) and very grateful for all the support from @HelmholtzMunich@PioneerCampus, and all the hard work of my lab members in the past 5 years! 🫶 More updates soon!
How are cell-cell interactions governing successful metastatic colonization in the liver? Have a look at our new paper in @nature that introduces an in vivo proximity screen to functionally test cellular interactions in a high-throughput manner. nature.com/articles/s41586-0… 🧵
Such work takes a village! I would like to thank @elettod for designing and cloning of all plasmids and vectors, Marie for support and guidance with animal experimentation, @snsf, @ETH_en, and @krebsliga for funding and everybody who contributed ideas, help, and reagents.
My PhD work in the @moorlab is out 🥳🤩🤪 Five year after that lunch break discussion with @AndreasMoor! Thanks Andreas for believing in our crazy outside-in screen and to ALL the people that helped along the way!
Researchers at ETH Zurich have uncovered how #Colorectal#CancerCell's colonise the liver. Their findings could open up new ways to suppress this process in the future. brnw.ch/21wLtkS@ETH_BSSE