The Ebola outbreak has been extremely fast moving, and the news has been mostly terrible News of potential trials of vaccines and therapeutics does lend some hope - but these are some way off Catch up on the latest developments with me here (link in reply 👇)

No paper as the final 90-day results are just being finalized today (June 11) - they last-observation carried forward 37 of the observations from 30d for the CCR presentation. Can debate the fine points of methods (I'm fine w/ it), but clear Tamiflu is out for ICU-level Influenza and it's an embarrassment to the field it took us this long to investigate properly. (and that many sites wouldn't even randomize to no Tamiflu! wtf are we doing... )

If you're *still* giving high dose vitamin C to critically ill people, it is really, *really* time to stop doing so

Decided to start taking things more seriously over at S*bst@ck and write more often Great to have people engage with the work!

Thought I would give Claude Fable a quick whiz as sounds exciting! As my entire job is biological research (although nothing spicy, mainly vaccine trials) it basically flags everything I do Unusable for me currently ☹️

If there are times we don't need gold standard evidence, and "aluminium standard" is enough, how do we know how much evidence we need My framework for deciding how much evidence is enough, and why sometimes people disagree (hint - it's not science!) munro-link.alasdairmunro.wor…

Dr Ally Munro giving some brilliant advice on handling conversations about vaccination in the CED #premierconference #PEM #EM #Emergencymedicine #Paediatricemergencymedicine

I just said to my 9yo son, “Some books are like snacking on sweets, and some books are like eating a succulent three course meal” Rich words from someone whose pre-adolescent reading diet was 99% Calvin and Hobbes

The first clinical trial of a ‘universal’ Sarbeco coronavirus vaccine at 2 NIHR facilities has shown that the vaccine is safe and has no significant side effects. The study took place at the Southampton Clinical Research Facility (@SouthamptonCRF) and the Cambridge Clinical Research Facility (@CambridgeCRF). It was sponsored by University Hospital Southampton NHS Foundation Trust (@UHSFT) and recruitment was supported by the Research Delivery Network (@NIHRrdn).

An AI-designed ‘universal’ coronavirus vaccine trialled at @UHSFT @southamptoncrf could help protect against future viruses before they emerge 👇 Experts say this could potentially save millions of lives and avoid costly lockdowns. 🔗 research.uhs.nhs.uk/news/new…

Why does medicine have such a history of implementing therapies, only to later gather evidence and discover that the intervention provided no benefit, or worse, actually harmed patients? How much evidence is enough? open.substack.com/pub/alasda…

The Ebola outbreak has been extremely fast moving, and the news has been mostly terrible News of potential trials of vaccines and therapeutics does lend some hope - but these are some way off Catch up on the latest developments with me here (link in reply 👇)

RT @cinarervanur: It was a pleasure to present the findings from our UK national cohort study on #CNS complications of #iGAS in children #E…

Kudos to the WHO The WHO involvement is very evident in the timeline markers on the chart (WHO alert, PHEIC declaration on May 17, Director-General visit to Ituri, high-risk assessment, etc.). This reflects a rapid, high-level coordinated international response to the Bundibugyo virus disease (BVD) outbreak. Bottom line The chart below captures a serious but actively managed situation. The reclassification PHEIC mobilization shows authorities and partners (DRC/Uganda MoH, WHO, CDC, etc.) catching up on surveillance, lab capacity, and response coordination — especially valuable in a conflict-affected area with population movement and mining-related travel. The 26 infected healthcare workers remain a red flag for nosocomial transmission that needs urgent attention. Uganda’s linked cases appear well-contained so far thanks to tracing. This is exactly the kind of data-driven situational awareness that PHEIC-level coordination is meant to support. Continued focus on diagnostics, IPC in health facilities, and community trust will be key to bending the curve further. @WHO @WHOAFRO @MarionKoopmans @SecRubio @CDCgov #EbolaDRC #Bundibugyo #PublicHealth #Outbreak #GlobalHealth

RT @cinarervanur: Plenary 2 at #ESPID2026: excellent summary by Greet Hendrickx on factors influencing vaccine confidence and vaccination b…

Join me for the latest updates on the Ebola outbreak Case numbers, misinformation (some from actual "experts"), potential therapeutics in the pipelines, and what this all means with me here If you find it useful please subscribe and share alasdairmunro.substack.com/p…