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Arash Bellafard @arashbe
Joined June 2009
  • Tweets 19
  • Following 207
  • Followers 78
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Arash Bellafard@arashbe
15 May 2024
Excited to share our latest research published in @Nature! We explored how working memory representations evolve and stabilize with practice, using simultaneous volumetric imaging of more than 73,000 neurons. Big thanks to my amazing team and collaborators! Special appreciation to @pgolshani and Alipasha Vaziri for their invaluable contributions. Let’s dive into the highlights! #Neuroscience #Research #Memory #Science #NeuralDynamics 🌟🔬🧠
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Peyman Golshani@pgolshani
3 Aug 2025
In these difficult times (all grants frozen) it is good to recognize the good that science can do. Very proud of our new paper on open-source 2P miniscopes! They can image dendrites in cortex and dentate granule neurons through an intact CA1. nature.com/articles/s41467-0…

Open-source, high performance miniature 2-photon microscopy systems for freely behaving animals

Nature Communications - Madruga and colleagues present an open-source, miniature 2-photon microscope that can fit on a mouse’s head. Using this system, the authors perform high-resolution...

nature.com
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9/ 🙏 Thanks to my incredible team and collaborators! Special shoutout to @pgolshani and Alipasha Vaziri for their invaluable contributions. #TeamScience
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10/ 🧠 Curious to learn more? Check out the full paper for a deep dive into the methods and findings. Link: nature.com/articles/s41586-0…

Volatile working memory representations crystallize with practice

Nature - Delay- and choice-related activities that are essential for working-memory performance drift during learning and stabilize only after several days of expert performance.

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8/ 🌐 These insights provide a deeper understanding of how working memory evolves with learning and could pave the way for new therapeutic strategies for cognitive impairments. #BrainHealth
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6/ 📈 Interestingly, while single-plane layer imaging showed some insights, it was the simultaneous volumetric imaging of up to 73,307 M2 neurons that revealed the full picture of this stabilization process. #CuttingEdgeTech
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7/ 🎯 Our findings highlight that delay-related activities crucial for working memory initially fluctuate but stabilize with practice. This could have implications for understanding learning and memory disorders. #ResearchImpact
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3/ ⏱️ Using optogenetic inhibition, we discovered that interfering with secondary motor neurons during the late-delay and choice periods drastically impairs task performance. #NeuralDynamics
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5/ 🧩 As the mice became experts, their working-memory representations during the late-delay epoch drifted initially but eventually stabilized. This drift-stabilize process is crucial for solidifying memory. #MemoryFormation
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4/ 🔬 Mesoscopic calcium imaging of the M2, RSA, and M1 cortices showed that late-delay-epoch-selective neurons emerged in the M2 as the mice learned the task. But why is this important? #BrainImaging
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2/ 🐭 We trained head-fixed mice to perform an olfactory delayed-association task. The mice had to identify and remember two sequential odors to make a decision. #Neuroscience
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Excited to share our latest research published in @Nature! We explored how working memory representations evolve and stabilize with practice, using simultaneous volumetric imaging of more than 73,000 neurons. Big thanks to my amazing team and collaborators! Special appreciation to @pgolshani and Alipasha Vaziri for their invaluable contributions. Let’s dive into the highlights! #Neuroscience #Research #Memory #Science #NeuralDynamics 🌟🔬🧠
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1/ 📄 Title: "Volatile working memory representations crystallize with practice" Link: rdcu.be/dH1Kl

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Ueli Rutishauser@UeliRutishauser
17 Apr 2024
Delighted to announce our latest paper. We discovered single-cell correlate of theta-gamma PAC. Hippocampal PAC cells participate in control of WM through information-enhancing noise correlations and long-range frontal interactions. @Nature @CedarsSinai nature.com/articles/s41586-0…

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Blake Madruga@BlakeMadruga
1 Apr 2024
Excited to share my PhD work in @pgolshani 's lab designing and building low-cost miniature 2P microscopes with everyone! They cost < $10k USD (even at low production runs), are fitted with 2 on-board SiPM detectors, and are completely open-source! 1/5 biorxiv.org/content/10.1101/…
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Pingping Zhao@PingpingION
6 Aug 2023
Excited to share our preprint, the work I’ve done in Golshani lab @pgolshani. Using UCLA Miniscope, I explored NAc neural representation of social interaction and identified representational deficit in Cntnap2 KO mice. More exciting results are coming! Stay tuned.
bioRxiv Neuroscience@biorxiv_neursci
6 Aug 2023
Accelerated social representational drift in the nucleus accumbens in a model of autism biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Jiannis Taxidis@JiannisTax
20 Nov 2018
My work at the @pgolshani lab is finally online! "Emergence of stable sensory and dynamic temporal representations in the hippocampus during working memory" Check it out: biorxiv.org/cgi/content/shor…

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Just setting up my Twitter. #myfirstTweet
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