@benranard profile picture
Benjamin Ranard @benranard

Intensivist at @ColumbiaMed | Learning Health Systems and Health IT | Formerly @DukeMedicine @PennMedicine @Penn_MSHP @Cornell

Joined August 2012
  • Tweets 116
  • Following 433
  • Followers 268
10 Photos and videos
Excited to share our protocol paper in BMJ Open describing the SEPTIC trials — pragmatic, multicenter RCTs testing whether interruptive SIRS-based EHR alerts improve timely sepsis care. And will be even more excited to share the trial results shortly. bmjopen.bmj.com/content/15/8…

Pragmatic, multicentre, factorial, randomised controlled trial of sepsis electronic prompting for...

Introduction Sepsis is a major cause of death both globally and in the United States. Early identification and treatment of sepsis are crucial for improving patient outcomes. International guidelines...

bmjopen.bmj.com
1
56
more replies
We aim to answer two key questions: ✅ Do these alerts improve sepsis care? ✅ Who should receive them? Huge thanks to our amazing collaborators across @Columbia , @WeillCornell , @nyphospital and more!
1
41
Min Qian, Matthew Cummings, David Zhang, Shing Lee, Jeremy Beitler, Jo Applebaum, Edward Schenck, Hassan Mohamed, Richard Trepp, Hanson Hsu, Jean Scofi, Will Southern, Sarah Rossetti, RN, PhD, Natalie Yip, Dan Brodie, Manish Sharma, Baruch Fertel, @JasonAdelmanMD
120
We created a mathematical model of SARS-CoV-2 immunity that looks at "Paxlovid Rebound" onlinelibrary.wiley.com/shar… @ccc1685 @m_datasci @Prof_Shadnaz @soojin_soojin @yoram66 #PaxlovidRebound #Paxlovid #COVID19 #COVID 1/6

1
3
1,081
more replies
Our modeling shows longer duration of Paxlovid treatment does not prevent rebound. Initiating Paxlovid treatment a few days later (a few days after symptom onset) does prevent rebound. However, the patient's immune system is already clearing the virus at this point. 5/6
1
263
These observations are based on mathematical modeling. Data from patients and additional research are needed to confirm these findings. Also, we did not model immunosuppressed patients. In the mean time, please follow the advice of your doctor and take Paxlovid as directed! 6/6
189
Benjamin Ranard retweeted
Joel Boggan@JoelBoggan
12 Sep 2022
Out @JHealthQuality: #pophealth didactics ⬆️confidence on team-based care strategies but translating to ⬆️ #health outcomes likely req #QI efforts across residency training @Duke_GIM @IMResidencyDuke #DukeOutpatientClinic @JPShoup @azaleakim @benranard journals.lww.com/jhqonline/F…

1
2
6
Out today, our work: heart rate variability and adrenal size provide clues to sudden cardiac death in hospitalized #COVID19 patients sciencedirect.com/science/ar… @soojin_soojin @m_datasci @kalijahterilli @Hirad7 John Ausiello @ColumbiaMed @nyphospital @CU_Cardiology

1
11
more replies
We also wondered whether adrenal insufficiency could be playing a role in the sudden cardiac death. Adrenal size was significantly smaller in the sudden cardiac death group (while all other organ weights were similar).
1
In conclusion, patients hospitalized with #covid19 with sudden cardiac death had lower RMSSD and smaller adrenal gland size than patients who died without sudden cardiac death. These exploratory findings need to be replicated in other cohorts.
Out today, our work on Identification of #Endotypes of Hospitalized #COVID19 Patients! frontiersin.org/articles/10.… @FrontMedicine #machinelearning 1/10

Frontiers | Identification of Endotypes of Hospitalized COVID-19 Patients

Background: Characterization of coronavirus disease 2019 (COVID-19) endotypes may help explain variable clinical presentations and response to treatments. Wh...

frontiersin.org
1
2
7
more replies
Thank you to our amazing team! @m_datasci, @kalijahterilli, @kwdoyle1, @claassen_jan, #MichaelPinsky, #GillesClermont, @yoram66, @Prof_Shadnaz, @soojin_soojin 10/10
1
2
1
@ColumbiaMed @ColumbiaNCC @PittCCM @CSULB
Load more