Joined February 2011
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๐ŸšจSuper proud of a new publication from our lab spearheaded by @MarieDeBorre, together with @UZLeuven, @ZOLziekenhuis and @azsintjan. We provide proof-of-concept that cell-free DNA (cfDNA) methylome analysis allows for early preeclampsia (PE) prediction. rdcu.be/dla4e

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Bernard Thienpont retweeted
๐Ÿ“ข #JobAlert The research group of @bernthie is looking for a lab technician. You can contribute to various interesting research projects. Apply before 11/03: kuleuven.be/personeel/jobsitโ€ฆ
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Bernard Thienpont retweeted
14 Feb 2025
Volg morgen en overmorgen van 10 u. tot 16 u. alle ๐Ÿฒ๐Ÿฌ๐Ÿฌ ๐—ฆ๐—˜๐—–๐—ข๐—ก๐——๐—˜๐—ก๐—Ÿ๐—˜๐—ญ๐—œ๐—ก๐—š๐—˜๐—ก tijdens @KU_Leuven Inside live op ROBtv. #robnieuws #robtv
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Bernard Thienpont retweeted
LISCO is looking for an experienced Business Developer in Single-Cell and Spatial Multi-Omics for Biomedicine to take our cutting-edge lab services and research capabilities to the next level.๐Ÿ‘‰ Apply here: kuleuven.be/personeel/jobsitโ€ฆ or feel free to share with your network!

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Bernard Thienpont retweeted
Are you active in #sequencing and want to show your research to leading researchers? Submit an abstract for #RNGS25: vibbio.tech/3ZY5IYl Present on stage with a poster pitch or during the poster sessions. The abstract deadline is 15 January 2025. #ngs #genomics #multiomics
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Bernard Thienpont retweeted
Many thanks @NatMetabolism for publishing and highlighting our research, all members of our lab, the excellent collaboration with @bernthie and especially first author @SteveStegen
Top Citations 2024: #20๐Ÿ†โœจ @GeertLab (@KU_Leuven) and co-authors describe the role of the serine synthesis pathway in osteoclast differentiation through #epigenetic regulation of NFATc1 expression ๐Ÿฆด๐Ÿงซ nature.com/articles/s42255-0โ€ฆ
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Bernard Thienpont retweeted
We are recruiting PhD students in cancer and metastasis biology! This is a fantastic program that brings together several leading European research institutes. Details below ๐Ÿ‘‡.
18 Nov 2024
๐Ÿ“ข Calling all future cancer researchers! Adaptmet is offering 16 MSCA PhD positions in cutting-edge metastasis research. Join us to shape the future of cancer science with exciting projects among Europeโ€™s best teams from top host institutions! Apply now ๐Ÿ‘‰adaptmet.eu/recruitment/
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Bernard Thienpont retweeted
๐Ÿ†Congrats to our PhD researchers Mio Aerden (@bernthie lab) and Yente Monnens (@JohnCreemers lab) for winning the 1st and 2nd prize at the Genetics Retreat NVHG graduate meeting. #proud klinischegenetica.mumc.nl/geโ€ฆ
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Bernard Thienpont retweeted
10 Jul 2024
Lannoo et al. examined whether rare autosomal trisomies revealed by noninvasive prenatal screening reflect fetal trisomy or confined placental mosaicism and whether they are associated with โฌ†๏ธ likelihood of adverse perinatal outcomes. Full correspondence: nej.md/3RVX34b
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Bernard Thienpont retweeted
We have a new 'Dr. House' in the house! PhD researcher Benjamin Huremagic participated in the #undiagnosedhackathon2024. Together with a bioinformatician from @UAntwerpen solving a case in only 2 hours: nieuwsblad.be/cnt/dmf2024060โ€ฆ @KU_Leuven @Nieuwsblad_be @JorisVermeesch

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amazing work and thoroughly deserved by @KateEStanley1 !
#eshg2024 awards ๐Ÿ† Early career award Kate Stanley๐Ÿ‘๐Ÿผ
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Bernard Thienpont retweeted
Prof. Joris Vermeesch shares updates on Implementing Genome Sequencing to Solve Rare Disease Cases in Belgium: Learnings from the Nationwide RCT BeSolveRD #ESHG2024
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Bernard Thienpont retweeted
Replying to @bernthie
@bernthie highlighting his recent multi-omics review (free to read link in quoted tweet) now at #ESHG24
Happy to share our deep dive into Methods and applications for single-cell and spatial multi-omics @NatureRevGenet, with the magnificent Katy Vandereyken, Alejandro Sifrim & Thierry Voet from the @KU_Leuven Institute for Single Cell Omics @CHG_CME rdcu.be/c6JjL
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Bernard Thienpont retweeted
Welcome to the last day of #eshg2024! Tune in on one of our symposia or educational sessions starting now.
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Bernard Thienpont retweeted
Great talk @ESHG from @KateStanly on deconvoluting cfDNA!
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paper alert ๐ŸšจFiguring out the cellular composition of tissues is essential for understanding diseases. DNA methylation analysis is particularly suited for this task, as deconvolution algorithms can untangle mixture signals from bulk samples into their individual components.
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For sequencing-based DNA methylomes, we also assessed how sequencing depth and uniformity affect performance. This resulted in a nuanced set of recommendations for optimal deconvolution, depending on the underlying research question and goal.

ALT Spongebob Squarepants GIF

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Thanks to @ridderkobe for expertise, persistence and diligence, to other members of the lab and reviewers for their insights, and @FWOVlaanderen and @Stkstichting for support! Happy deconvolving to you all! rdcu.be/dH55V

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