🌎👩‍🔬 For 15 years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵 Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open. doi.org/10.1101/2024.07.30.6…

In mitochondria, respiratory supercomplexes (blue) pump protons across crista membranes to create an electrochemical gradient, fueling adenosine triphosphate (ATP) synthase (pink) to regenerate ATP—the energy currency of life. Now, cryo–electron tomography captures these supercomplexes in their native organization, illuminating how the coordinated action of these molecular machines drives life’s fundamental energy conversion. Learn more this week in Science: scim.ag/3FQ6bEh

We present DRGN-AI for fast, ab initio cryo-EM reconstruction! * learns a neural field from unposed images, * designed for single-shot reconstruction of unfiltered datasets, * finds new states missed by prior approaches! Teamwork led by @ZhongingAlong drgnai.cs.princeton.edu/ 1/

Examples from our Protein Common Assembly Db now on @biorxiv_bioinfo with @QifangXu. Viable assemblies for all Xray structures (EPPIC, @josemduarte), clustered w/ cryoEM, NMR assemblies by Pfam architectures stoichiometry symmetry interfaces. @buildmodels @PDBeurope @pdbj_en

@chaconlaborg Last week, after a minor ransomware attack the Spanish cybersecurity authorities (CCN y COCS) decided to disconnect from the internet the whole Spanish national research council (CSIC). Our primary research agent is inoperative and nobody cares. It´s shameful.

Mini Symposium on Structural Bioinformatics in memoriam Angel Ramirez Ortiz, a great scientist prematurely passed away 10 years ago. Monday May 28. #cbmso

El Gobierno solo gastó tres de cada 10 euros presupuestados para I D en 2017 elpais.com/economia/2018/04/… vía @elpais_economia

Public and private science investment in Spain...

SOS para salvar la investigación en España cadenaser.com/programa/2018/…