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Hard to overstate how pleased I am that the #flywire consortium converted our FAFB ("Full Adult Fly Brain") EM volume into a connectome, and that the resulting science has been (and will be) so impactful. Thanks to everyone involved.
2 Oct 2024
Here it is! A huge milestone in neuroscience – the complete connectome of the fly brain from the FlyWire team (@FlyWireNews). In this special issue, we have 9 research articles. I’ll try to summarize them in a couple threads starting here 🧵
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Davi Bock retweeted
Jun 9
Just published yesterday, the #BANC! A full central nervous system (CNS) connectome of a limbed animal enables us to trace sensory-motor arcs and understand how the CNS controls the body. rdcu.be/fncjS #neuroscience @Nature, Video by @quorumetrix, sound on! 1/18
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Davi Bock retweeted
Jan 22
For over twenty years, many dedicated researchers around the world have worked to realize the dream of connectomics. I'm especially indebted to the talented members of my laboratory, past and present. And I've been lucky to benefit from so many powerful collaborations.
The winner of the 2026 Pradel Research Award is H. Sebastian Seung (@SebastianSeung) of @PrincetonNeuro! He is being honored for for transformative advances in computational neuroscience. Learn more about his discoveries: nasonline.org/award/pradel-r… #NASaward #neuroscience
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Davi Bock retweeted
13 May 2025
This to me signals a serious escalation on the assault on free speech. usermag.co/p/hasan-piker-det…
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Davi Bock retweeted
4 Feb 2025
"The future is an infinite succession of presents, and to live now as we think human beings should live, in defiance of all that is bad around us, is itself a marvelous victory." 4/4
Howard Zinn, "The Optimism of Uncertainty" (2004)
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Davi Bock retweeted
26 Nov 2024
Final week to register for the Crete meeting - judging from the people who already signed up, this is shaping up to be a super exciting week for Drosophila circuits enthusiasts.
2 Nov 2024
Fellow Fly Folks - registration for the Crete Fly Circuits meeting just opened! This will be a fun and exciting conference for everyone working on neural circuits & behavior in Drosophila 🪰. June 15 - 21/2025. And yes, the venue is right by the sea 🌊.
sites.google.com/view/crete-…
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Davi Bock retweeted
26 Nov 2024
The BRAIN Initiative has driven unprecedented progress in neuroscience, but a 40% funding cut threatens this momentum. Restoring funding would help solve more mysteries of the brain and developing life-changing treatments. #studyBRAIN nature.com/articles/s41593-0…
22 Nov 2024
The BRAIN Initiative has been an engine of innovation but is now fighting for its survival. Here we discuss why BRAIN is special and why we must all fight for it now nature.com/articles/s41593-0… @TheHongLab @DrZoePhD @bjmarlin @doristsao @moriel_z @HongkuiZeng XiaokeChen ZivWilliams
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Davi Bock retweeted
26 Nov 2024
This is a really heroic experiment recording associative learning neurons in the fly brain over two hours while two flies interact with one another. This device and this approach can generally enable many more kinds of social interaction experiments
26 Nov 2024
We recorded the activity of neurons within this network during 2 hours of social interactions. Interestingly, as the animals became more sociable the baseline and locomotor-related activity greatly diminished in MBONs previously implicated in aversive learning.
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Davi Bock retweeted
23 Nov 2024
Whole-brain spatial organization of hippocampal single-neuron projectomes science.org/doi/10.1126/scie…
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Davi Bock retweeted
15 Nov 2024
The $3B Human Genome Project was started under a Republican administration and later acknowledged by the Obama admin to have returned $141 to the economy for every $1 spent. Science has a higher ROI than any other category of government spending.
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Davi Bock retweeted
19 Nov 2024
Thanks @dddavi for taking a pic the moment I first saw our cover of @Nature! A magical time to be at @SfNtweets #sfn 2024. To the future!
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Davi Bock retweeted
9 Sep 2024
📣NEURO FACULTY JOBS! 🧠
University of Oxford opened *2* positions for Associate Professors of Neuroscience! Come be our colleague!
Applications due: noon, 18 Nov 2024
More info: my.corehr.com/pls/uoxrecruit…
@UniofOxford @OxfordDPAG @OxNeuro @PembrokeOxford @hilda_beastoxf
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Davi Bock retweeted
4 Nov 2024
I've combined some of these together into a new #neuro #visualization "In the eye of a fly":
Using the @FlyWireNews visual system wiring diagram, #Brian2 spiking #neuron simulator, and #blender. Information flow through the chiasms, across a topographic map.
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Davi Bock retweeted
14 Nov 2024
😶
ALT Image by Didier Descouens
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For Reasons it just came to mind that retina great @whatishealth21 Peter Sterling (computer-based volume EM circuit reconstruction in 1984!) was also a Freedom Rider. penn.edu/news/peter-s... ryehistory.org/stories/pete...
ALT McGuire Stevens Sterling 1984 J Neurosci Fig 4
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Protists are awesome! Neat to see the biochemical & structural mechanisms for rapid cell shape change start to get worked out. :)
9 Nov 2024
What. The. Fuck?!? 🤯🤯 biorxiv.org/content/10.1101/…
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Tom Reese has passed. He was a truly pioneering explorer of neuronal ultrastructure, and really nice guy to talk to. I am grateful to have known him. mbl.edu/news/obituaries/thom…
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Davi Bock retweeted
4 Nov 2024
Interested in working on a state-of-the-art connectomics pipeline at its birthplace as a postdoc? We’d love to hear from you! :)
mrc.tal.net/vx/mobile-0/appc…
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strong reuse of open FlyWire and FAFB image & manual tracing data in this interesting-looking segmentation effort: arxiv.org/pdf/2401.03043v1
Idea seems to be to embed features from small pre-segmented fragments and train them to hook up correctly using FlyWire & FAFB ground truth
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