Musculoskeletal bioengineering laboratory at Duke University, headed by Dr. Lou DeFrate. 🏥📊📈📚

Joined June 2017
129 Photos and videos
DeFrate Lab retweeted
Ended a jam-packed day at #ORS2025 with talks from @thehopefulscie1 and others to discuss interdisciplinary approaches to solutions for OA👏 I am constantly inspired by Hope, who presented on the metabolome of knee OA patients following 18-mo weight loss interventions #ORSSMC
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DeFrate Lab retweeted
Starting #ORS2025 with a phenomenal talk from @SadeWill93 on how #aging and the immune system alter and magnify IVD in both males and females, and more so, how #pain fits into this complex relationship 👏🏼🧬
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DeFrate Lab retweeted
We are looking forward to seeing everyone at #ORS2025. Come check out our work! @ORSsociety @OrsMeniscus @DukeOrtho @DukePathDept
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DeFrate Lab retweeted
Congratulations to our newest PhD candidate, @allisonrbinsn, on her successful prelim yesterday! Thankful to have such a beautiful day to celebrate today. @DukePathDept @DukeOrtho
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DeFrate Lab retweeted
The first paper from PhD student @MaxineOlson27 is out. She developed an algorithm to distribute a ground reaction force into multiple vectors to allow for calculation of midfoot and ankle moments using standard clinical gait lab equipment. sciencedirect.com/science/ar… @MU_MCW_BME
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DeFrate Lab retweeted
Congrats @thehopefulscie1 Avery and @ronjune2 on a comprehensive and exciting review!
Excited to share our Year in Review on Molecular #Biomarkers of #Osteoarthritis 🎉 We dive into recently published gene, protein, & metabolite biomarkers across joints & sample types. Big strides made, but there’s still work to do! Early detection awaits! @ronjune2 @OACJournal
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DeFrate Lab retweeted
It is great to finally share our systematic review on structural extracellular matrix components in soft tissues in osteoarthritis! Congratulations to my co-authors Iwan Raza and @Sarah_JB_S. boneandjoint.org.uk/Article/…
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DeFrate Lab retweeted
Check out our comprehensive transcriptomic comparison of inner and outer zone meniscus tissue to cartilage and passaged meniscus cells to identify meniscus specific genes @SciReports. nature.com/articles/s41598-0… @DukeOrtho @KaileenFei @DaDchasse @nnakelly2

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DeFrate Lab retweeted
Check out our latest paper in @FrontBioeng showing that healthy but not osteoarthritic meniscus-derived matrix scaffolds can promote ex vivo meniscus repair. This was a great collaboration with our clinical colleagues @DukeOrtho @FirooziSaman @DaDchasse frontiersin.org/journals/bio…
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DeFrate Lab retweeted
Excited to be representing @jboerckel and the future Panebianco Lab™️ at #BMES2024!
Super proud of these amazing scientists from our lab presenting at #BMES2024! Departments with faculty searches coming: don't miss @cpane94's Future Faculty Poster tomorrow! @BMESociety
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DeFrate Lab retweeted
Congrats Kelsey Collins, PhD @ucsfmskcenter @UCSFOrthosurg for incredible achievements in osteoarthritis research! Awarded NIH Director’s New Innovator Award w $1.5M in funding, she's pioneering therapies to combat musculoskeletal pain and inflammation. tiny.ucsf.edu/kc
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DeFrate Lab retweeted
Congrats to @ORSsociety board member @KelseyHCollins on this outstanding achievement and recognition!
Thrilled and grateful to receive this award. We hope to shift paradigms in the complex role of fat interorgan crosstalk on musculoskeletal pain with aging and obesity. Honored to be counted among the #NIHHighRisk labs & these exceptional folks @ucsfmskcenter @UCSFOrthosurg @UCSF
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DeFrate Lab retweeted
Thrilled and grateful to receive this award. We hope to shift paradigms in the complex role of fat interorgan crosstalk on musculoskeletal pain with aging and obesity. Honored to be counted among the #NIHHighRisk labs & these exceptional folks @ucsfmskcenter @UCSFOrthosurg @UCSF
Early-stage investigators proposed #innovative high-impact research ideas for the @NIHDirector’s New Innovator Award. See the projects the awardees will pursue: commonfund.nih.gov/newinnova… #NIHHighRisk
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Congratulations, Kelsey!!
Thrilled and grateful to receive this award. We hope to shift paradigms in the complex role of fat interorgan crosstalk on musculoskeletal pain with aging and obesity. Honored to be counted among the #NIHHighRisk labs & these exceptional folks @ucsfmskcenter @UCSFOrthosurg @UCSF
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DeFrate Lab retweeted
3 Oct 2024
‘Jolet always has a great question to ask and helps everyone to really think about their research ideas and plans. She is excellent at teaching people in the lab and is an outstanding citizen of NDORMS.’
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DeFrate Lab retweeted
Fantastic work by @ArinOestreich and @NHarasymowicz and team - did you know that what your parents ate before you were born will affect your bone health?
Replying to @NHarasymowicz
@NHarasymowicz and I are excited to share our latest manuscript showing maternal high-fat high-sugar diet impairs bone quality in two generations of mouse offspring in @JOrthopRes. @Farsh_G @khmoley onlinelibrary.wiley.com/doi/…
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DeFrate Lab retweeted
I'm incredibly honored to be selected as a Spotlight Speaker for the #ORS2025 Annual Meeting. Can't wait to discuss digital twins and the future of image-based outcomes assessment in orthopaedics!
We are thrilled to introduce the Spotlight Speakers for the #ORS2025 Annual Meeting, taking place Feb 7-11 in Phoenix, AZ. These thought leaders will share their innovative insights, shaping the future of #orthopaedic science. View speakers talk titles: bit.ly/3N5Sim2
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DeFrate Lab retweeted
Super proud of @cpane94 for his fantastic talk today @ISBM_society! Great job, Chris! #ISBM2024
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DeFrate Lab retweeted
Excited to share my work with @jboerckel at #ISBM2024 ! @ISBM_society
Super proud of @cpane94 for his fantastic talk today @ISBM_society! Great job, Chris! #ISBM2024
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DeFrate Lab retweeted
Hi @OrsSpineSection members and trainees! Join @SheynLab and myself for a virtual networking event on October 9th at 11am pacific. Register here: ors.memberclicks.net/spsoc10…
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