@dvconti profile picture
David Conti @dvconti
Joined January 2014
  • Tweets 17
  • Following 189
  • Followers 139
3 Photos and videos
David Conti retweeted
Population and Public Health Sciences at USC@uscpphs
16 Jun 2021
How is #cancer risk different among #diverse populations? Faculty @dvconti and @ChrisHaiman are making it their mission to find out. bit.ly/3guB6H7 @genome_gov
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David Conti@dvconti
16 Jun 2021
Constructing and evaluating risk models in non-European ancestry populations is essential to broaden the impact of genomic medicine. Excited to be a part of this group @ChrisHaiman @johnwitte @GENES_PK and others supported by the consortium. @KECKSchool_USC @uscphs @USCBiostat
National Human Genome Research Institute@genome_gov
16 Jun 2021
Research studies are starting to use polygenic risk scores to determine a person’s inherited risk for diseases. @NIH is awarding grants to develop methods that will improve how polygenic risk scores can be used to predict disease in diverse communities. bit.ly/3wednRj
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David Conti@dvconti
1 Mar 2021
New paper examining rare variants in the DNA repair pathway and the risk of colorectal cancer. Uses integrated Bayesian Risk Index, a method to incorporate prior information @uscphs @USCBiostat @KeckMedUSC pubmed.ncbi.nlm.nih.gov/3362…

Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer - PubMed

This study provides new insights into the genetic predisposition to colorectal cancer, which has potential for translation into improved risk prediction.

pubmed.ncbi.nlm.nih.gov
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David Conti retweeted
USC Schaeffer@USCSchaeffer
28 Jan 2021
People previously infected with COVID-19 should postpone getting vaccinated so more vulnerable groups can be prioritized, argues Schaeffer Center’s Neeraj Sood @USCPrice, and Abigail Horn and @dvconti of @KECKSchool_USC. calmatters.org/commentary/my…

Those previously infected with COVID-19 should delay getting a vaccination

Evidence points to past COVID-19 infections producing strong immune responses which looks to be as effective as a vaccine.

calmatters.org
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David Conti retweeted
Maarten van Smeden@MaartenvSmeden
16 Jan 2021
How to become a SUCCESSFUL academic: a guide 1/n
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David Conti@dvconti
7 Jan 2021
New paper with @CG_Howe and @ChatziLida on prenatal metal mixtures and child blood pressure. Uses advanced analysis techniques for mixtures (BKMR etc.): pubmed.ncbi.nlm.nih.gov/3340… @uscphs @USCBiostat @KECKSchool_USC

Prenatal metal mixtures and child blood pressure in the Rhea mother-child cohort in Greece - PubMed

Prenatal exposure to high levels of molybdenum and lead, particularly in combination, may contribute to higher BP at age 4. These early effects appear to persist throughout childhood, contributing to...

pubmed.ncbi.nlm.nih.gov
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David Conti@dvconti
7 Jan 2021
hJAM: Hierarchical Modeling for Joint Analysis of Marginal Summary Statistics - method for MR and TWAS and other omic data. Our @Lai42491643 @nmancuso_ new approach just published: pubmed.ncbi.nlm.nih.gov/3340… @uscphs @USCBiostat @KECKSchool_USC

A Hierarchical Approach Using Marginal Summary Statistics for Multiple Intermediates in a Mendelian...

Previous research has demonstrated the usefulness of hierarchical modeling for incorporating a flexible array of prior information in genetic association studies. When this prior information consists...

pubmed.ncbi.nlm.nih.gov
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David Conti@dvconti
5 Jan 2021
LUCID paper pubmed.ncbi.nlm.nih.gov/3150… and R package: cran.r-project.org/web/packa…

A latent unknown clustering integrating multi-omics data (LUCID) with phenotypic traits - PubMed

Supplementary materials are available at Bioinformatics online.

pubmed.ncbi.nlm.nih.gov
David Conti@dvconti
5 Jan 2021
Congrats to @ChatziLida team for NIEHS 2020 paper of the year! Uses LUCID to identified children at high risk for liver injury, integrating prenatal PFAS exposures and metabolomic profiles. factor.niehs.nih.gov/2021/1/… @uscphs @USCBiostat @KECKSchool_USC
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David Conti@dvconti
4 Jan 2021
Our @BurcuDarst new paper on trans-ancestry GWAS for prostate cancer. We develop a genetic risk score and estimate absolute risk in four major ancestry groups. nature.com/articles/s41588-0… @uscphs @USCBiostat @KECKSchool_USC @USC_Research

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David Conti@dvconti
24 Dec 2020
The surge continues in Los Angeles County. As of 12/23/20, we estimate 3.7% of the county's population is currently infected and daily deaths are rising. Latest model estimates at uscbiostats.github.io/COVID1… @uscphs @USCBiostat @KECKSchool_USC
David Conti@dvconti
19 Dec 2020
Latest estimates for our LA County COVID model are at uscbiostats.github.io/COVID1… Current estimated percentage of infected (both observed and unobserved) is 2.88%. More detail at: medrxiv.org/content/10.1101/… @USCBiostat @uscphs @KECKSchool_USC
David Conti@dvconti
18 Dec 2020
Our new paper modeling the COVID-19 epidemic in Los Angeles County. Includes risk-stratified estimates of case fatality rates and infection fatality rates across different time points. medrxiv.org/content/10.1101/… @usc @USCBiostat @uscphs
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David Conti@dvconti
4 Sep 2020
Why COVID-19 vaccines need to prioritize 'superspreaders' theconversation.com/why-covi… via @ConversationUS

Why COVID-19 vaccines need to prioritize ‘superspreaders’

A team of experts argues that after taking care of essential workers, COVID-19 vaccinations should be given to the greatest transmitters of the virus, who are mostly the young.

theconversation.com
Replying to @blekhman
Made me think of this one
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David Conti@dvconti
18 Oct 2018
Great discussion for high performance computing today at the Core C meeting @USCBiostat
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