#ENDpoiNTs_EU strives to develop a testing battery of human relevance to screen the impact of endocrine disruption on neurodevelopment. Funding from @EU_H2020.
🧠Advancements in neurotoxicity testing! 3D BrainSphere models based on human induced pluripotent stem cells allow thorough neural characterization. Spike sorting distinguishes various neuronal subtypes. Read more: doi.org/10.3390/cells1209127…#neuroscience#neurotoxicity
🐀 Exciting new research! A method to quantify 23 steroid hormones from adult and neonatal rat liver & plasma was established using enzymatic treatment, SPE & LC-MS/MS. Read more: doi.org/10.1016/j.talanta.20…#LCMS#EDCs#steroidhormones
🧠 Take a look at your brain!
🔬 These images capture neural progenitor cells' journey to human #neurons. Adherence protocols provide targeted cell cultures for our focused research.
Exciting new research from our partners in Paris, reveals that embryonic exposure to a mixture of EDCs found in human amniotic fluid can significantly alter gene expression of neurodevelopmental genes and decrease tadpole motility. Read the study here: doi.org/10.3390/ijms24032588
Recent research from our partners in Paris @BDemeneix@umr7221 highlights that even short-term developmental exposure to low levels of bisphenol F can adversely affect neurogliogenesis and olfactory behavior in adult mice doi.org/10.1016/j.envint.202…
A new study from our @UmeaUniversity partners presents an in silico approach for a first-tier identification of compounds with potential endocrine activity in Receptor-mediated molecular initiating events doi.org/10.1021/acs.chemrest…
A new study from our @humantechnopole partners presents an approach for in vivo/ in vitro alignment of neurodevelopmentally relevant processes by benchmarking transcriptomic profiles of brain organoid against fetal corticogenesis. Read more here: doi.org/10.1038/s41398-022-0…
A recent publication from our partners at @UniUtrech shows effects of pesticides on neuronal activity and network development
doi.org/10.1016/j.neuro.2022…
The next EURION Cluster Annual Meeting is held in Amsterdam on 30-31 Jan 2023 🥳
On 30 Jan there is an online session open to any stakeholders. In this session, the cluster projects highlight their key achievements so far.
#EDCs#H2020@HorizonEU#EURIONeurion-cluster.eu/eurion-clu…
The ENDpoiNTs coordinator, Prof. @JoelleRuegg we will presenting in the upcoming symposium on Endocrine disrupting chemicals and Human Health. Last day of registrations! For information see:
tinyurl.com/2s4zvk4d
🚨New @ERGO_EU publication alert🚨
An atlas of #thyroid#hormone receptors’ target genes🔍🧬
A unique compilation of sequencing data focusing on thyroid hormone T3, its receptors, modes of action, targets & roles, an easy-to-use & convenient tool!
👀👉bit.ly/3AziO1e