Cardiac Electrophysiology and Genetics
Joined July 2009
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167 Photos and videos
Mark Perrin retweeted
12 Aug 2025
An early post-biblical explanation of the meaning of Jesus’ death (2nd-century AD).
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Mark Perrin retweeted
14 Nov 2024
John's claim that Jesus is God culminates in this: the man who is God gave his life for each one of us.
That sense of value is something we cannot measure.
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Mark Perrin retweeted
6 Nov 2024
But also, of course, the classic text for election days: "Put not thy trust in princes, nor in the son of man, in whom there is no help. His breath goeth forth, he returneth to his earth." (Psalm 146).
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Mark Perrin retweeted
8 Oct 2024
"Have you not known? Have you not heard? The Lord is the everlasting God, the Creator of the ends of the earth. He does not faint or grow weary; his understanding is unsearchable. He gives power to the faint, and to him who has no might he increases strength." - Isaiah 40:28-29
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24 Sep 2024
Unusual noise on an ICD lead. Noise is seen on the farfield Can-RV Coil (lower), but not seen on the near-field RV Tip-Ring (upper), even though it seems to be sensing the noise. @jeffrey_vinocur @narrowQRS
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24 Sep 2024
The over sensing occurs prior to noise on the far-field. I suspect plain old TWOS - he has had similar in the past. But I can't explain the noise that follows on the Can-Coil. It is only seen on this tracing.
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Mark Perrin retweeted
21 Sep 2024
I don’t love it. Although I don’t know if undersensing risk is different with R waves >20 and sensitivity 1.2 than R waves 5 and sensitivity 0.3?
Also we have low threshold for DFTs anyway because of complex hardware config and atypical patients and so may already have data
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Mark Perrin retweeted
21 Sep 2024
One of the several arguments for the era of DFT testing, including VF induction with "least sensitive" sensing. Reassurance in the event that decreasing sensitivity in the future is needed for TWOS or phrenic myopotential oversensing.
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17 Sep 2024
An unusual ICD tracing. PMVT organises to VT. ATP changes the near field signal, but the far-field suggests ongoing VT. Device thinks this is TWOS. PVC causes transition and a shock delivered.
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17 Sep 2024
Discussing with some friends, we thought most likely functional block causing 2:1 at the lead tip (the second wave being a local T wave), while VT ongoing. PVC peels back refractoriness to 1:1. Thoughts?
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18 Nov 2023
If the English first encountered the Aztec instead of the Spanish would they remain a people? #RIHLive
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18 Nov 2023
If Alexander the Great never existed would our world be any different? Gabriel Perrin age 12 #RIHLive
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Mark Perrin retweeted
23 Jan 2023
We showed that PAC frequency is the single most potent predictor of #Afib pubmed.ncbi.nlm.nih.gov/2429…, but does the origin matter? @StaceyHowellMD used our HOLIDAY trial data to show: PACs delivered from the PVs ➡️#Afib > other LA or RA sites pubmed.ncbi.nlm.nih.gov/3668… @B_Naz_MD @UCSF
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12 Jan 2023
Cryoballoon PVI with temporary phrenic nerve palsy. At redo PVI with RF, phrenic nerve overlies antral vein in proximity to cryoballoon scar. Isolation was transmural except in the posterior carina. #epeeps
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Mark Perrin retweeted
7 Jan 2023
Excited to share our work on diagnostic challenges in isolated cardiac sarcoidosis and genetic cardiomyopathies. @B_Naz_MD @MasriAhmadMD @crchenMD jacc.org/doi/10.1016/j.jacc.…
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7 Jan 2023
This is the most common post Covid complication in my clinic - (which is Cardio EP). Referral is made for ‘palpitation and tachycardia’. Most recovered completely over 6-12 months. Not a new phenomenon - was certainly seen with other viruses pre Covid. 1/2
7 Jan 2023
It’s a strange phenomenon… I’ll walk for 10 min. Feel great. Then start a REALLY slow jog. In less than 1 min my HR is 137. I can keep it there.. but only for 4-5 miles. Bla- at this stage is ~2.4. HR creep is sig. after 4-5 miles/ same pace my HR is 144. I don’t go there.
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7 Jan 2023
2/2 As well described in this thread, it may manifest predominantly as a loss of Zone 2 (mid range) HR - a form of inappropriate sinus tachycardia but without the resting increase in HR.
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