PUFAs are more effective at promoting tumor growth than saturated fats. Researchers administered a cancer-inducing chemical to all groups in the rat study and then examined how different dietary fats influenced tumor development. - Saturated fats alone (beef tallow or coconut oil) produced relatively low tumor development, similar to the low-fat control group. - Adding a small amount of PUFA (just 3% sunflower oil) to a diet otherwise composed of saturated fats dramatically increased tumor formation. - Rats fed a diet containing 3% sunflower oil & 17% saturated fat developed roughly twice as many tumors as rats fed either the saturated fats alone or the low-fat diet. - Increasing sunflower oil from 3% to 20% did not substantially increase tumor formation further, suggesting that relatively small amounts of PUFA were sufficient to produce most of the tumor-promoting effect. A few important notes: Much of the early research investigating the biological effects of PUFAs was conducted before the widespread adoption of the “heart-healthy vegetable oil” hypothesis and saturated fat fear mongering. Studies from the 1950s through the 1970s frequently examined the health concerns of PUFAs, including their susceptibility to oxidation and their effects on cancer development. Another important observation from this study is that relatively small amounts of PUFA were sufficient to substantially increase tumor formation. This raises an important consideration when evaluating modern studies: many “low-PUFA” comparison groups still contain meaningful amounts of polyunsaturated fats (they don’t keep PUFAs low enough). If a threshold effect exists, comparing one moderate-PUFA diet against another may underestimate the health improvements of true low PUFA diets.

Every time I actually try fish for more than a couple of days, I slide closer to the Peat interpretation: all PUFA is bad, even omega-3. Just quit the salmon experiment after only 14 days. - Way worse weight loss than beef - Sunburn - General sense of food not being satisfying - Increased appetite for heavy cream - Didn't feel quite 100% much of the time ("malaise?") Maybe it's a dose-makes-the-poison thing and the correct dose is "no more than 1-2 fish meals a week?"

Biology boils down to redox it seems. Fuck redox up and you fuck with cellular energy production

Hard core! We've got ROS theory of obesity representation at @realCSF ! So happy to see someone go through this particular learning qpathway @2ketodudes @DrEades @Peter_InNorfolk BTW the final of this slide included @fire_bottle but I missed that shot.

I am excited to learn about an independent third party food testing lab @test_your_food, launching soon. They won’t just test food, they will interpret and properly assess the data to help us all better understand what those results actually mean in the context of metabolic health. Food testing is certainly very important! It helps us better understand what we are buying and how food actually impacts our health, especially within the modern food system that has undergone some big shifts in production methods, and ultimately in the food we consume.

Just wrapped up the committee hearing for our Food Freedom & Raw Milk Bill where Chelsie and I testified, advocating for small farmers and freedom of choice. If the bill receives a majority vote in committee, it will move to the House floor for a full vote, and then on to the Senate. Huge thanks to Chair BeGole @BrianB1328452 for allowing this grassroots effort to move forward and for showing support for farmers and consumers. And thank you to Representative @matthewmaddock for sponsoring the bill and leading the charge to cut red tape for small farmers and protect true food freedom.

Increased seed oils in red blood cells → decreased risk of diabetes

With eight months left on its charter, the Department of Government Efficiency (DOGE) has ceased to exist according to the Trump Administration. Radio talk show host @DavidGornoski was at the center of the storm when @ElonMusk endorsed a role for Ron Paul in DOGE and he joins today's Liberty Report to discuss those heady early days and how the principles of DOGE will remain alive and continue to grow. Also today: the sad departure of Marjorie Taylor Greene.