@infoecho @domenjemec reviewed Conway's Law and the history of genome assemblers to see how including agents in academic labs will shape the research software ship. PIs will bifurcate further: either they'll ship more or end up even more removed. gptomics.com/blog/conway_law…

As academic audit culture grows (now pre-approvals for conferences, foreign collabs, etc), I hope students will remember there's another way: academia built on mutual trust/obligation through collective effort My take on the neoliberal academic ecosystem: youtu.be/PGO4qgfm7DU

Congrats Ada Lau (one of our ODYSSEY trainees) getting her research highlighted at the #MoffittScientificSymposium @MoffittNews

At #MoffittScientificSymposium, Ada Lau shares research investigating immunosuppressive features of the multiple myeloma tumor microenvironment following CAR-T therapy. Findings revealed CD8 immune responses between complete response and progressive disease samples, highlighting interferon pathway activation in responders and TNF-alpha signaling in progressive disease.

Science does not have to be complicated: Direct injection of an immune therapy drug into tumour reduces side effects without compromising efficacy. nature.com/articles/d41586-0…

"Why wait 6 months for reviewer 2 when you can get roasted by an #AI in seconds?" A metascientist's thought exercise. bsky.app/profile/shahanmemon… Meanwhile, an AI society announces it's incorporating LLMs into its review process. aaai.org/aaai-launches-ai-po…

AI can accelerate discovery through algorithmic optimization, but translating those discoveries into impact remains a human endeavor.

On the lack of compelling evidence that medical AI is improving patient care, and what to do about it, a @NatureMedicine editorial nature.com/articles/s41591-0…

CGPA paper is finally out!

When polishing scientific figures for publication, I try to limit fonts font sizes to reduce visual noise. But doing this by hand is tedious. So I vibe coded a web app to standardize text in SVGs: jef.works/SVG-Text-Standardi… Try it out! Spot the differences. Hope it's helpful

#ScienceSaturday ❓ How can we turn T-cells into cancer-fighting “soldiers” without changing their DNA? ➡️ A new study in Nature Biotechnology introduces an all-RNA platform that can turn T-cell genes on or off using epigenetic CRISPR tools called CRISPRoff and CRISPRon. Instead of cutting or rewriting DNA, this method “reprograms” genes by adding or removing chemical marks — allowing researchers to boost or silence key immune functions safely. ➡️ The team showed this can enhance CAR T-cell therapies, helping immune cells better recognize and attack tumors while reducing potential side effects linked to traditional gene editing. 🌟 Congratulations to senior authors Alex Marson, Luke Gilbert, Brian Shy, and Justin Eyquem of UCSF, Arc Institute, and Gladstone Institutes for this exciting advance — a big step toward the next generation of precise, safer immunotherapies. 🔗 Read more in Nature Biotechnology: doi.org/10.1038/s41587-025-0… @LukeGilbertSF @UCSF @UCSFCancer @UCSFMedicine @arcinstitute @GladstoneInst @j_eyquem

A recent special issue of Science explores the immune system at the molecular and cellular level and how it has evolved to govern multiple facets of human health. Learn more: scim.ag/45xh33a

SmartImpute is now online with Cell Reports Methods cell.com/cell-reports-method…

RSG SE-USA presents America’s 3rd #ComputationalBiology Symposium taking place December 11–13, 2025 at the University of Florida in St. Petersburg.  This is a great chance for students to connect and plan for the future of the field!

If you’d like to present at the symposium, submissions are being accepted until Friday, August 15.  Contact and submission details are in the flyers!

Researchers have been sneaking secret messages into their papers in an effort to trick AI tools into giving them a positive peer-review report Read the full story: go.nature.com/4eVTIwC

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by @US_FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe, rapidly progressing genetic disease... all in an astounding 7 months. Best of all, the infant patient shows apparent benefit. Congratulations to @kiranmusunuru, Rebecca Ahrens-Nicklas, and other team members for this heroic and inspiring effort, which has implications for the hundreds of millions of patients that suffer from thousands of genetic diseases. drive.google.com/file/d/1Jfk…

Congratulations to Michael J. Schell, Ph.D., FASA. Well deserved! 🎉🎉🎉 #Moffitt #ASA #Biostatistics #CancerResearch

Using ROICellTrack on urothelial carcinoma, we identified distinct cancer-immune cell mixtures linked to transcriptomic & morphological signatures. Check out our recent paper with @song_xiaofei and @UrogerliMD. academic.oup.com/bioinformat… #SpatialTranscriptomics

Thanks to the @KayYowFund we will be able to begin some exciting research challenging current treatment paradigms in ovarian cancer that will hopefully improve outcomes. Thank you so much for your generous support!