ENGINEERING BIOLOGY (SynBio)
AI, nano semiconductors and OMICS engineering for creating the human embedded system!!
Building a global alliance of biofoundries
Biofoundries provide an integrated infrastructure to enable the rapid design, construction, and testing of genetically reprogrammed organisms for biotechnology applications and research. Many biofoundries are being built and a Global Biofoundry Alliance has recently been established to coordinate activities worldwide.
nature.com/articles/s41467-0…
Bio‐informational futures: The convergence of artificial intelligence and synthetic biology
embopress.org/doi/full/10.15…
A machine learning Automated Recommendation Tool for synthetic biology
Automated Recommendation Tool (ART), a tool that leverages machine learning and probabilistic modeling techniques to guide synthetic biology in a systematic fashion, without the need for a full mechanistic understanding of the biological system. Using sampling-based optimization, ART provides a set of recommended strains to be built in the next engineering cycle, alongside probabilistic predictions of their production levels.
nature.com/articles/s41467-0…
Application of combinatorial optimization strategies in synthetic biology
nature.com/articles/s41467-0…
Build-a-cell: Engineering a synthetic cell community
mdpi.com/2075-1729/11/11/117…
Creation of a bacterial cell controlled by a chemically synthesized genome
science.org/doi/10.1126/scie…
Integrating artificial with natural cells to translate chemical messages that direct E. coli behaviour
nature.com/articles/ncomms50…
Linking Engineered Cells to Their Digital Twins: A Version Control System for Strain Engineering
This paper presents an approach for physically linking engineered cells to their digital footprint—we called it digital twinning. This enables the tracking of the entire engineering history of a cell line in a specialized version control system for collaborative strain engineering via simple barcoding protocols.
pubs.acs.org/doi/10.1021/acs…
A global forum on synthetic biology: the need for international engagement
A Global Forum on Synthetic Biology is needed to engage policymakers with practitioners across borders at the highest level. The international community needs a global confidence-building measure focused on discussing policy futures for the age of engineering biology.
Engineering Biology Research Consortium (EBRC); Genome Project Write (GP write); International Gene Synthesis Consortium (IGSC); Global Biofoundry Alliance (GBA); iGEM Foundation (iGEM); BioBricks Foundation (BBF); Bioindustrial Manufacturing and Design Ecosystem (BioM); Organisation for Economic Co-operation and Development (OECD)].
nature.com/articles/s41467-0…
ENGINEERING BIOLOGY RESEARCH CONSORTIUM
A Research Roadmap for the Next-Generation Bioeconomy (Engineering Biology 2019)
roadmap.ebrc.org/2019roadmap…
Microbiome Engineering Roadmap (2020)
roadmap.ebrc.org/2020-roadma…
Engineering Microbiomes—Looking Ahead (Viewpoint)
pubs.acs.org/doi/10.1021/acs…
Enabling Defense Applications through Engineering Biology (2020 Roadmap)
ebrc.org/focus-areas/roadmap…
Engineering Biology & Materials Science: A Research Roadmap for Interdisciplinary Innovation (2021)
roadmap.ebrc.org/2021-roadma…
Engineering Biology for Climate & Sustainability (2022)
roadmap.ebrc.org/engineering…
An Assessment of Short-Term Milestones in EBRC’s 2019 Roadmap, Engineering Biology (2023)
roadmap.ebrc.org/2019-roadma…
Engineering Biology for Space Health (2024 Roadmap)
roadmap.ebrc.org/engineering…
All the roadmaps (EBRC main page)
roadmap.ebrc.org/