cellGeometry employs non-negative geometric deconvolution (NGD), an intuitive vector projection method featuring non-negative matrix regularisation in high-dimensional gene space. Using matrix operations, scales to massive datasets and is ultrafast.
🥳Happy to present our manuscript on division plane orientation with Thijs de Zeeuw and @dolfweijers. Thankful to the co-authors Che‐Yang Liao, @KBuerstenbinder and especially #MGX team @RichardSmithLab@StraussSoe for their contribution🙏
3D cell organisation in pseudostratified epithelia is far more complex than commonly pictured, with up to 14 neighbour changes along the cell. #cellgeometry 3/9