Epitranscriptomics #PhaseSeparation
m6A-modified #EnhancerRNA & YTHDC1-BRD4 assemble transcriptional condensate
Methylation-inscribed nascent transcripts/MINT-seq detects >3-fold more m6A peaks than MeRIP-seq
Stringtie annotate eRNAs & (promoter upstream antisense) uaRNAs, 24% & 48% are m6A in MCF7 cells, higher than pre-mRNAs
dCasRx-FTO-mediated m6A erasure
@wli2019 @MolecularCell 2021
cell.com/molecular-cell/full…
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9 Apr 2021
In our latest issue: Characterization of transcripts emanating from enhancer Eβ of the murine TCRβ locus.
Read it here ➡️ buff.ly/3s3ICeH
#enhancerRNA #transcription
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17 Mar 2021
Now in Early View: Characterization of transcripts emanating from enhancer Eβ of the murine TCRβ locus.
Read it here ➡️ buff.ly/3bTZEHp
#enhancerRNA #TCRbeta
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26 Jun 2018
#Integrator navigates enhancers with #RNApolII and cleaves the 3' end of #enhancerRNA. @nature
nature.com/articles/nature14…
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