If you’re exploring neural plasticity, fear conditioning, or inhibitory subtypes in the amygdala, let PubMed.ai accelerate your research workflow.
What if your fear circuitry is reshaped in ways you’ve never imagined?
Today’s new blog dives into the microcircuit-level inhibitory remodeling that drives fear learning—and we’re kicking it off with a quick quiz to test your intuition.
Smarter search, faster synthesis, deeper insights—right when you need them.
Find the answer here: medium.com/@harryblackwood/h…
#Neuroscience #Amygdala #FearLearning #Interneurons #PubMedAI
🔬 Research Focus: Heterogeneous Plasticity of Amygdala Interneurons in Associative Learning & Extinction
Find More Research: pubmed.ai/?utm_source=X&utm_…
Recent work highlights how diverse interneuron subtypes within the amygdala—particularly parvalbumin (PV), somatostatin (SST), and VIP neurons—shape the precision and adaptability of emotional learning.
Key Insights
🧠 Plasticity Is Not Uniform:
Interneuron populations show subtype-specific plasticity patterns during both learning acquisition and fear-extinction phases.
🎯 Circuit-Level Modulation:
PV interneurons regulate timing and gain control, SST interneurons modulate dendritic integration, while VIP cells disinhibit key excitatory pathways.
🔄 Emotional Memory Stability:
The interplay of these plasticity mechanisms ensures flexible behavioral responses during shifting emotional states.
Understanding how these circuits adapt offers deeper insight into fear conditioning, maladaptive emotional memory, and potential targets for anxiety and PTSD interventions.
#Neuroscience #Amygdala #Interneurons #SynapticPlasticity #FearLearning #PTSDResearch #BrainCircuits
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🔬 Research Focus: Heterogeneous Plasticity of Amygdala Interneurons in Associative Learning & Extinction
Find More Research: pubmed.ai/?utm_source=X&utm_…
Recent work highlights how diverse interneuron subtypes within the amygdala—particularly parvalbumin (PV), somatostatin (SST), and VIP neurons—shape the precision and adaptability of emotional learning.
Key Insights
🧠 Plasticity Is Not Uniform:
Interneuron populations show subtype-specific plasticity patterns during both learning acquisition and fear-extinction phases.
🎯 Circuit-Level Modulation:
PV interneurons regulate timing and gain control, SST interneurons modulate dendritic integration, while VIP cells disinhibit key excitatory pathways.
🔄 Emotional Memory Stability:
The interplay of these plasticity mechanisms ensures flexible behavioral responses during shifting emotional states.
Understanding how these circuits adapt offers deeper insight into fear conditioning, maladaptive emotional memory, and potential targets for anxiety and PTSD interventions.
#Neuroscience #Amygdala #Interneurons #SynapticPlasticity #FearLearning #PTSDResearch #BrainCircuits
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30 Oct 2025
I think they sell the green KitKats at World Market. I used to hang out at one.
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8 Aug 2025
1/ Excited to share a new preprint!
Our latest study uncovers how serotonin precisely controls the “time window” for fear learning, ensuring that our brains link cues (CS) & threats (US) only when it’s adaptive.
#Neuroscience #FearLearning
biorxiv.org/content/10.1101/…
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Excited to share this new publication on observational fear learning and interoceptive threat, where we show that fear of bodily symptoms can be acquired when observing fear reactions to aversive bodily symptoms in others #interoception #fearlearning
sciencedirect.com/science/ar…
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People of #S4SN2022! Don't miss poster A13 by Hilda Engelbrektsson on #FearLearning and the #endocannabinoid system and poster A8 by @M_R_Jones on the #endocannabinoid system and #AffectiveTouch!
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30 Oct 2022
My second PhD 🎓 paper is out where we examined the effect of subjectively measured #SleepDisruptions 😴 on #FearLearning processes in individuals with a range of #PTSD symptom severities. 🧵[1/3]
sciencedirect.com/science/ar…
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18 Oct 2022
Congratulations to my TNPal, officemate, and friend @JohnFrance_WSU on his first 1st author publication! Great work by the team @DTP_Wayne and collaborators. Read it now: journals.sagepub.com/doi/pdf… #fear #amygdala #trauma #extinction #fearlearning #threatreactivity #development
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24 Jul 2022
The Influence of Vicarious #FearLearning in “Infecting” Reactive #ActionInhibition
frontiersin.org/articles/10.…
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12 Apr 2022
#FearLearning Would any good soul be willing to share a quick screenshot of pupil response to the delivery of shock? (Not CS /-, the actual delivery). ⚡️⚡️ 🙏
(Ideal with some information about filtering)
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13 Dec 2021
Some #ACNP2021-inspired reading:
"The Role of Learning in Threat Imminence and Defensive Behaviors"
ncbi.nlm.nih.gov/pmc/article…
#threat #fearlearning #learning #pavlovianconditioning @PavlovSociety #science #neuroscience #research #phdchat #phdlife
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19 Aug 2021
Thrilled to welcome my friend and colleague Dr. @TZbozinekPhD to the Twittersphere!
Currently working at @Caltech with the incredible @DeanMobbs, follow Tomislav for some seriously innovative work on human #FearConditioning and #FearLearning!
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19 Apr 2021
How did I miss this great work from @LabCarlson?
#LocusCeruleus drives #catecholamine release in the cerebellum. Manipulation can impair (or improve!) cognitive functions including #FearLearning, sensorimotor integration, working memory in mice.
Relevant to #PTSD, #TBI
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11 Mar 2021
Really cool paper links #CGRP neurons with #fearlearning behavior. Thanks 4 sharing @neuroayogi! @BIRC_at_UCLA @UCLABrainSPORT @ASnyderPhD @BRI_UCLA @UCLASemelFriend @SfNtweets
@sonyalynanne4 @lindz4RandF @tcthomas127 @Neurosharp
Han S @CellPressNews 2015: pubmed.ncbi.nlm.nih.gov/2618…
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Welcome to the @labgas_kuleuven @OGPLeuven Twitter club to our PhD student @LaurenPattyn! Follow her work on #interoception #fearlearning #symptomperception #psychogastroenterology, with @GuadagnoliLivia
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20 Oct 2019
Important work by @PsychSarah1 and 🔥 topic in fear learning! Don’t miss 👇#sfn2019 stop by poster U6 on Wednesday! #fanselowlab #fearlearning #resilience #suseptability @PsychScience @SfNtweets
19 Oct 2019
Excited to head to #sfn2019 tomorrow!
If you’re around Wednesday afternoon, why not stop by poster U6 to see my work investigating susceptibility versus resilience to the effects of stress on fear learning?
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