New publication out: SAT in PJI!
🔎 Forty-two studies (n = 2524 patients)
• Practice varies (U.S. vs Europe)
• Success ~70–74%
✔️ Consensus definitions proposed (SAT vs EAT)
Let’s check it out!
doi.org/10.1093/cid/ciag251#MSIS#EBJIS#OrthoID#PJI@MSISorg
【Mycobacterial Cultures in Orthopedic Samples】@JBoneJtInfect Oct 2024 #OrthoID#Keyarticle
👉Out of 6,162 samples (2017–2022), 22 patients had M. tuberculosis and 6 had NTM isolated🇬🇧
👉To detect one new bone/joint mycobacterial infection, 229 cultures are needed
👉In low-TB settings, targeted mycobacterial cultures may be more effective than routine testing
@MSISorg @EBJIS_ #IDMedEd#IDFellow@MayoClinicINFDjbji.copernicus.org/articles…
【Osteomyelitis Complicating Sacral Pressure Ulcers: Whether or Not to Treat With Antibiotic Therapy】@CIDJournal 2019
👉Very helpful article on sacral pressure ulcers! Highly recommend reading!
✍️No evidence of benefit of antibacterial therapy for stage IV sacral pressure ulcers without concomitant surgical debridement and wound coverage
academic-oup-com.mclibrary.i…#OrthoID#Keyarticle#IDMedEd#IDFellow@BradSpellberg@DWong9
【Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis】@TheLancet 2015 #OrthoID#Keyarticle
✍️Always the landmark paper on the duration of therapy for native vertebral osteomyelitis!
👉RCT 🇫🇷 71 institutions
👉N=351
👉6 weeks is not inferior to 12 weeks (cured at 1 year: 91%)
pubmed.ncbi.nlm.nih.gov/2546…#IDMedEd#IDFellow@MayoClinicINFD@MSISorg @EBJIS_
【Optimal Duration of Antibiotic Therapy in Patients With Hematogenous Vertebral Osteomyelitis at Low Risk and High Risk of Recurrence】@CIDJournal 2016 🇰🇷
👉Important study that suggested high-risk patients (MRSA, undrained abscess, hemodialysis) may need prolonged therapy more than 8 weeks!
pubmed.ncbi.nlm.nih.gov/2691…#IDMedEd#IDFellow#OrthoID@MayoClinicINFD#Keyarticle
【Follow-up MRI in vertebral osteomyelitis】Am J Neuroradiol 2007 #OrthoID#Keyarticle
Q: Do we need f/u MRI?
A: Not recommended, incorrelation w/ clinical features
Worse compared w/ baseline
👉Vertebral body/disk space enhancement
👉bone marrow edema
pubmed.ncbi.nlm.nih.gov/1741…
【Imagining of pyogenic native vertebral osteomyelitis】Spine J 2023 #OrthoID#Keyarticle
✍️PET/CT: Sen 93% Spe 80%
✍️MRI: Sen 90%, Spe 72%
✍️Ga: Sen 95%, Spe 88%
👉Ga and PET/CT may be justified when early NVO or MRI is contraindicated
pubmed.ncbi.nlm.nih.gov/3675…@MayoClinicINFD
【The Rush protocol for 2-stage revision for PJI】Bone Joint J, 2020 #OrthoID#Keyarticle
Q. What is the Rush protocol?
A: 3-month ppx post-reimplantation can reduce the reinfection rate
👉RCT (N=185)
👉Failure: 13% (3m) vs 29% (no ppx)
pubmed.ncbi.nlm.nih.gov/3247…
#KeyArticle
"Cigarette smoking often results in #nicotine dependence. With use of #ecigs as an alternative source of nicotine, it is important to assess dependence associated with e-cigarette use. "
"This study assesses dependence among current and former adult e-cigarette users on #cigarettes and e-cigarettes, compared with dependence on cigarettes." - @NCBI
Read the full paper here:
pubmed.ncbi.nlm.nih.gov/3219…#THR#THRworks#HarmReduction
#KeyArticle from the September 2018 issue of @JVascSurg (#openaccess free to download until October 31, 2018). #VisualAbstract
Anti-hypertensive medication adherence in chronic type B aortic dissection is an impt consideration in the management debate.
bit.ly/2OsYIeK