ALT a picture representing the recently opened #myeloMATCH clinical trial, #CCTG ALC10. Exploring a new treatment option for older adults with acute myeloid leukemia #AML who may not be able to tolerate intensive chemotherapy.
MyeloMATCH data highlight how NGS can streamline fusion detection in AML/MDS and support faster diagnostic profiling.
Read more: bit.ly/4dQRrCF#AML#leusm
Intended for healthcare professionals. Independently supported by Thermo Fisher Scientific. Funders are allowed no influence.
On the latest episode of the Bench to Bedside podcast, Dr. Tara Lin and Dr. Jesus Gonzalez Lugo share an update on #MyeloMATCH, a first-of-its-kind national clinical trial designed to bring precision medicine to patients with #AML. Tune in today: bit.ly/3Jet1Uu
ALT Three people sit around a table in a recording studio, with microphones, papers, and water bottles on the table.
NGS shows high concordance with cytogenetic assays in myeloMATCH, supporting a role in rapid fusion detection in AML/MDS.
Learn more: bit.ly/4dQRrCF#AMLsm#leusm
Intended for healthcare professionals. Independently supported by Thermo Fisher Scientific. Funders are allowed no influence.
From biopsy to biology in <72h-MyeloMATCH is basically ‘precision oncology on fast-forward’. At #DAVAWhistler, Dr. Eric Winer (@DanaFarber) presents rapid multi-omic profiling → smarter AML/MDS trial assignment at scale.
Precision oncology is no longer “next.” It’s becoming the operating system for cancer care.
In late 2025, the FDA approved imlunestrant with a liquid-biopsy companion diagnostic for ESR1-mutated breast cancer [1]. Regulators have also now formalized how ctDNA/MRD can support drug development in curative-intent solid tumors [2]. And NCI’s next-gen precision trials ComboMATCH, MyeloMATCH, iMATCH are already underway [3]. 🧬
That shifts the bottleneck from discovery to execution: testing access, turnaround time, reimbursement, and trial matching. The competitive edge won’t come only from better drugs, but from better systems ⚕️📉
The real question for leaders: build genomic infrastructure now or watch outcomes and investment concentrate elsewhere.
🤔 Where is precision oncology still overhyped, and where are health systems still moving dangerously too slowly?
[1] [fda.gov/drugs/resources-info…](fda.gov/drugs/resources-info…) ([U.S. Food and Drug Administration][1])
[2] [fda.gov/media/183874/downloa…](fda.gov/media/183874/downloa…) ([U.S. Food and Drug Administration][2])
[3] [cancer.gov/about-nci/organiz…](cancer.gov/about-nci/organiz…) ([Cancer.gov][3])
#PrecisionMedicine#Oncology#LiquidBiopsy#CancerCare#Biotech
[1]: fda.gov/drugs/resources-info… "FDA approves imlunestrant for ER-positive, HER2-negative, ESR1-mutated ..."
[2]: fda.gov/media/183874/downloa… "Guidance for Industry U.S. Food and Drug Administration"
[3]: cancer.gov/about-nci/organiz… "NCI-MATCH NCI National Cancer Institute"
Fred Hutch's @MinFang17 presenting work at #ASH25 showing chromosome genomic array testing (CGAT) improves diagnostic yield in patients with #AML and #MDS and has the potential for better risk stratification - a @theNCI myelomatch and @SWOG report. ashpublications.org/blood/ar…
Fred Hutch's Xiaoyu Qu presenting work at #ASH on improving karyotype success for myeloMATCH. Enhanced workflows boosted karyotype yield in AML samples, ensuring more patients receive accurate cytogenetic data for precision trial enrollment. ashpublications.org/blood/ar…
Wrapped up a great (and 1st!) @eaonc Fall Meeting in Philly! 🌆 Great talks on innovative tx, trial design and 📈role of AI. Great mentorship for 🐣🕵️
🌟Exciting things ahead in #MyeloMATCH#leusm
🎉 to @keruakous of @GACancerCenter leading EAA241, an important Ph II MM trial!
Analytical performance of the NCI-myeloMATCH assay – a rapid turnaround genomic profiling assay for myeloid disorders. From @AMPath member Dr. Cecilia Yeung and colleagues from @fredhutch and @theNCI.
Full text: jmdjournal.org/article/S1525…