New from Lehner lab: OpenSplice — ~600k variants across 608 exons. Largest splicing saturation mutagenesis dataset by far. SpliceAI still the top performer among 4 modern models tested (incl. Pangolin, SpliceTransformer, AlphaGenome). biorxiv.org/content/10.64898…

OpenSplice: the impact of half a million mutations on the alternative splicing of 600 human exons #RareDisease #Genetics biorxiv.org/content/10.64898…

Excited to announce #OpenSplice @gioia_40ni quantified the impact of >500,000 mutations on the alternative splicing of 600 human exons biorxiv.org/content/10.64898… results.hgi.sanger.ac.uk/Ope… @OpenTargets @sangerinstitute @CRGenomica #cshlsymp26 #RNA2026 @RNASociety

数据库存储类似操作系统，是一个非常重要非常基础的软件 理论和应用场景什么的都很清晰和完备，不过要深度把玩是需要付出很多代价的 无论何时，数据库存储都是最核心的基础设施 数据库存储都贯穿整个职业生涯，可持有几十年 这块可以长期拥有，一直研究下去，且越陈越香 因为数据是石油，是黄金，数据就是一切 没了数据，还能做什么 数据库存储决定数据模型和应用架构 决定业务模型和商业变现方式 用系统编程语言实现系统软件，如：数据库、存储 Erlang: OpenRiak, Apache CouchDB ... Go: TiDB, etcd, CockroachDB ... Rust: TiKV、SurrealDB ... C/C : PostgreSQL、MariaDB/MySQL、ScyllaDB ... Java: Apache Cassandra, Apache HBase ... Storage/File System：OpenMediaVault、OpenZFS、Ceph ... 其实，消息队列/消息中间件也可理解为持久性、分布式文件系统或数据库 可以一并学习和研究，储备更多核心能力 世界是消息、事件驱动的 消息代理、消息中间件、消息引擎，一个重要的基础设施 以下是一些可以关注的： 1、Apache基金会 Apache Kafka、Apache RocketMQ、Apache Pulsar、Apache ActiveMQ 2、Erlang 驱动的 RabbitMQ、ejabberd、EMQ X 3、Data Distribution Service（DDS） eProsima Fast DDS、OpenSplice 一个蛮棒的商业模式和服务形态：消息通信服务提供商 WhatsApp 可理解为消息通信服务的成功典范

the github repo isn't up yet since it still needs some work also SampleServer is a placeholder name (after i changed it from OpenSplice to not get sued), let me know if anyone has any good name ideas because i ran out of cool sounding words to put together

- Fast DDS - Cyclone DDS - Connext DDS（RTI） - OpenSplice DDS

Thank you for your comment! I previously examined Fast RTPS, Connext, and OpenSplice (Community Edition). I would like to try CycloneDDS in addition.

so many open source "OmniBot"! 70% ROS "classic", 30% ROS 2 Dashing w Eclipse Cyclone DDS and OpenSplice DDS adlink-ros.github.io/doc/neu…

The new release of ROS 2 Dashing Diademata is here. This release brings many new packages and an updated version of the OpenSplice RMW provider. See: ow.ly/ItVN50vqUrd @rosorg

Just got OpenSplice #DDS tuned on an Intel NUC and #ROS2 is running much smoother. Thanks @ADLINK_Tech @Intel #robotics #robot #engineering #rover #tech #stem #stemedu #phdlife

❤ @roverrobotics🤖 helping with #ROS2 OpenSplice #DDS and @ADLINK_Tech @intel #AI with #AWS #RoboMaker

Tests sending an ImageCompressed in #ROS2 in local machine. Fast-RTPS still has serious problems with large images (800x600 and larger), sensor and default QoS. OpenSplice is solid even with 4K images @rosorg @EProsima @opensplice_dds

今日ros2のDDSのfastrtpsとopenspliceとconnextの評価してみた。 単純なレイテンシー評価ではfastrtpsが一番早かったんだけど、共有メモリ使ってないのか、loネットワークの遅延がめっちゃ効いて遅くなった。 一方connextはloネットワークの遅延に左右されず一定レイテンシーだった

はてなブログに投稿しました ROS2 Tutorialsをやってみた ~Openspliceのインストール~ - RoboTry robotry.hatenablog.com/entry… #はてなブログ

@ADLINKTech_usa Vortex #OpenSplice It's the most advanced, widely used implementation of the #OMG #DDS standard. #fogcomputing #edgecomputing #military

#PrismTech featured in Jane's 360 - Australian Hawkeis to receive Vortex OpenSplice data platform janes.com/article/74300/aust… @IHS4DefRiskSec

#Australia #Tech Thales Australia Selects PrismTech’s Vortex OpenSplice for Integral Computing System dlvr.it/PmjsMs

Thales Australia Selects PrismTech's Vortex OpenSplice for Integral Computing System paper.li/RanjanSinha_/150142… #dsei

Thales Australia Selects PrismTech’s Vortex OpenSplice for Integral Computing System | Business Wire businesswire.com/news/home/2…

Thales Australia Selects PrismTech’s Vortex OpenSplice for Integral Computing System financialbuzz.com/thales-aus…