💫🌟Transcriptomic Signatures Associated With Outcomes in Recurrent #prostatecancer Treated With Salvage Radiation, Androgen-Deprivation Therapy, and #Enzalutamide: Correlative Analysis of the #STREAM Trial🌟💫
🔍 Key Findings from STREAM Trial on Recurrent Prostate Cancer!
@Daniel_J_George@DukeGUCancer Dr Andrew J. Armstrong Rhonda L. Bitting, MD
🎯 Study Focus:
🟠 Combining enzalutamide, salvage radiation & ADT in biochemically recurrent prostate cancer.
🟠 Using Decipher assay to predict gene expression efficacy.
💡 Insights:
🟠 Luminal differentiated subtype & higher ADT score ➡️ Positive Outcomes 🌟
🟠 Luminal proliferating phenotype, PTEN loss & homologous repair deficiency ➡️ Progression within 3yrs 🚫
🟠 Suggests some tumors resist androgen receptor blockade 🛡️
✳ Relevance:
🟢 Use transcriptomic signatures to pinpoint men for enhanced therapy or alternative methods. 🔁
@OncoAlert@OncoReporte@urotoday@JCOPO_ASCO#ProstateCancer#STREAMstudy#Transcriptomics#CancerResearchascopubs.org/doi/abs/10.1200…
Testing the water in nearby Jacob’s Creek. We measured pH, turbidity, salinity, nitrate and phosphorus levels, and the data we collected will be used by real scientists at the Watershed Institute! #science#fifthgrade#beartavernpride#streamstudy
We’ve had a very busy day taking part in orienteering, a stream study and a village study. We’ve finished our day with a campfire and toasted marshmallows! 🌲 🔥 🌲
@penguinclass5
#Hathersage#StreamStudy#Orienteering#Campfire
Today in science class, students tour the middle school campus to gain a better understanding of a watershed and those pesky phragmites plants. #streamstudy