Some conversations don't just inspire you. They help you find your direction. Official trailer out now. #EkDisha #CEOLife #vmmca #triplenegative #blitzscaling

🔔‼️Study alert! Patients with metastatic #triplenegative breast cancer #TNBC planning to be treated with Sacituzumab Govitecan can enroll on the SIMONE study combining SG with nivolumab (PD-L1) or SG with nivolumab plus relatlimab (LAG3 inhibitor) @YaleCancer #bcsm NCT06963905

Awesome chemo day! My good friend, Mark, joined me. 6th out of 12th chemo for weekly. Then I will have 4 more chemos, 3 weeks apart. Wonderful day. I really enjoy my chemo appointments so much. #breastcancer #triplenegative #breastcancerwarrior #triplenegativebreastcancer #chemo

🧵 Prognostic Impact of Driver Mutations in Primary Myelofibrosis (PMF) 🎤 Excellent slide by Dr. Rawan Almohamady at the 15th Annual Conference of the Saudi Society of Blood and Marrow Transplantation (SSBMT) 🇸🇦 🧬 Driver Mutations Are Not Prognostically Equivalent The major driver mutation in PMF significantly influences overall survival. 🟢 CALR-Mutated PMF 🏆 Best prognosis among all driver mutations. Median overall survival: 17.7 years 🟠 JAK2 V617F-Mutated PMF Median overall survival: 9.2 years 🔵 MPL-Mutated PMF Median overall survival: 9.1 years ⚫ Triple-Negative PMF 🚨 Worst prognosis. Median overall survival: 3.2 years 🧬 CALR Mutation Type Matters 🟢 Type 1 / Type 1-like CALR ⭐ Most favorable subtype. Median overall survival: 10.3 years 🟡 Type 2 CALR Median overall survival: 3.1 years ➡️ Type 2 CALR behaves more aggressively and may resemble JAK2-mutated disease or worse. 🧠 Why CALR Type 1 Is Favorable Associated with: Lower leukemic transformation risk Better response to therapy Lower thrombosis risk More indolent disease biology 🚨 Triple-Negative Disease No JAK2, CALR, or MPL mutation. Frequently associated with: High-molecular-risk co-mutations Inferior survival Higher AML transformation rate ➡️ Early transplant consideration is often warranted. 🧮 Impact on Risk Stratification Mutation profile is incorporated into: MIPSS70 MIPSS70 v2.0 GIPSS These models guide: Prognosis Timing of allogeneic HSCT Clinical trial selection 🩸 Practical Clinical Implications Favorable Biology 🟢 CALR type 1 without HMR mutations Observation or JAK inhibitor if symptomatic Transplant often deferred Intermediate Biology 🟠 JAK2 or MPL Risk based on clinical and molecular context High-Risk Biology ⚫ Triple-negative or HMR mutations Strong consideration for early allogeneic HSCT 🧠 Clinical Pearls 🔹 Always distinguish CALR type 1 from type 2. 🔹 Triple-negative PMF is biologically aggressive. 🔹 Prognosis depends on both driver and additional mutations. 🔹 Molecular information should directly inform transplant timing. 📝 Take-Home Message In PMF: 🏆 CALR type 1 → best prognosis ⚖️ JAK2/MPL → intermediate prognosis 🚨 Triple-negative → worst prognosis ➡️ Driver mutation status is one of the most powerful prognostic variables in modern PMF management. #Myelofibrosis #PMF #CALR #JAK2 #MPL #TripleNegative #MIPSS70 #GIPSS #AlloSCT #MPN #SSBMT #KFSHRC #Hematology 🩸🫛🧬🇸🇦

🔬‼️ When brain metastases appear could be a key factor in the survival of patients with advanced #breastcancer 🧠 🧪 A new subgroup analysis from the @GEICAM RegistEM study, recently published in the journal Therapeutic Advances in Medical Oncology, provides real-world evidence on how central nervous system involvement (#CNS) impacts clinical outcomes. 📊 From the study, which analyzed 1,947 women with advanced breast cancer, it was found that 18% developed brain metastases. Of these, 25% already had CNS involvement at the time of diagnosis, with a median #survival of 26 months, compared to only 9 months in those who developed metastases during the disease. 🧬 Relevant differences were also observed according to subtype. #HER2 and triple-negative tumors were the most likely to develop brain metastases early. In particular, patients with #triplenegative breast cancer showed the worst survival, with a median of just 6 months after the diagnosis of brain metastases. 💡 These results reinforce the importance of having therapies with intracranial activity, especially in higher-risk subgroups, and highlight the need to advance strategies for the prevention and management of #metastases in the CNS. 💜 Thank you to all the authors, researchers, and collaborating centre teams for this important work! 📝 The full press release is available below for more information: ➡️ geicam.org/wp-content/upload…

In women ≥70 years with nonmetastatic #TripleNegative #BreastCancer, #AdjuvantChemotherapy was associated with improved breast cancer–specific and overall survival compared to no chemotherapy. ja.ma/4mfAYLT

Sometimes the hardest battles are fought within. Yet courage, faith, and love can turn even the darkest diagnosis into a story of strength. 💫Triple Negative: A Tale of Love, Faith, and Surrender by @aarti_kpathak is a deeply moving journey of resilience and hope in the face of breast cancer. A story that reminds us that while the disease may carry the name triple negative, the human spirit never has to. 📖 Grab your copy: garudalife.in/triple-negativ… #TripleNegative #AartiPathak #CancerSurvivor #FaithAndStrength #BookRecommendation #InspirationalReads #GarudaPrakashan #IndianAuthors #HopeAndHealing

The ADC era is here. 🎙️ @JAMouabbi & @PTarantinoMD ▶️ Watch on YouTube - youtu.be/Skt3jGMBncM 🎧 Listen on Spotify, Apple Podcasts, iHeartRadio, CastBox, & Amazon Music #ADCs #TripleNegative #BreastCancer #OncologyPodcast #CancerResearch #ClinicalTrials #MedEd

Discover a deeply moving story of resilience, hope, and inner strength in Triple Negative: A Tale of Love, Faith, and Surrender by @aarti_kpathak . An inspiring journey that reminds us how love and faith can shine through even the darkest moments. 📘💛 A story that stays with you long after the last page. Buy link: garudalife.in/triple-negativ… #TripleNegative #AartiPathak #InspirationalReads #TrueStrength #FaithAndHope #BookLovers #IndianAuthors #GarudaLife

Triple-negative isn’t one disease. 🎙️ @JAMouabbi @PTarantinoMD ▶️ Watch on YouTube - youtu.be/Skt3jGMBncM 🎧 Listen on Spotify, Apple Podcasts, iHeartRadio, CastBox, & Amazon Music #TNBC #TripleNegative #BreastCancer #OncologyPodcast #CancerBiology #ClinicalOncology #MedEd

Sharing a special literary moment from the Mumbai Authors’ Meet ✍️ Watch @aarti_kpathak signing copies of her heartfelt book Triple Negative: A Tale of Love, Faith, and Surrender—a powerful story of resilience, devotion, and healing. Grateful to all the readers and attendees at Title Waves, Mumbai, for making this event truly memorable. 📚✨ #TripleNegative #AartiPathak #BookSigning #MumbaiAuthorsMeet #GarudaPrakashan #IndianAuthors #BookLovers #LiteraryEvents

An inspiring Book Signing session with @aarti_kpathak at Title Waves, Mumbai Authors' Meet! ✍️📖 Her powerful book Triple Negative: A Tale of Love, Faith, and Surrender is a heartfelt journey of courage, resilience, and unwavering belief in the face of life’s toughest battles. A story that reminds us that even in adversity, hope prevails. Get your copy today: 🔗 Buy here: garudalife.in/triple-negativ… #TripleNegative #AartiPathak #BookSigning #MumbaiAuthorsMeet #IndianAuthors #BookLovers #MustRead

🎥 A powerful conversation unfolds. Our author @aarti_kpathak speaks about her book Triple Negative: A Tale of Love, Faith, and Surrender with @sankrant Sanu, Founder & CEO of Garuda Prakashan. A moving reflection on courage, belief, and surrender. 📖✨ #TripleNegative #AartiPathak #AuthorTalk #BookDiscussion #IndianAuthors #BookLovers #GarudaPrakashan

✍️📚 Book Signing Moment at Goa Book Festival! Our author @aarti_kpathak signing copies of her book Triple Negative: A Tale of Love, Faith, and Surrender A heartfelt story that has touched many readers. Visit our stall and grab your signed copy! #GoaBookFestival #BookSigning #AartiPathak #TripleNegative #IndianAuthors #BookLovers

✨ Book Signing at Goa Book Festival 2026 ✨ Meet @aarti_kpathak , author of 📖 Triple Negative: A Tale of Love, Faith, and Surrender A deeply moving narrative of resilience, hope, and inner strength—this book touches the heart and stays with you long after the last page. 🗓 6 February 2026 ⏰ 5:00 PM – 6:00 PM 📍 D. B. Bandodkar Ground, Panaji 🎟 Entry Free | 10% Discount on All Books Join us for an inspiring author interaction and book signing at the Goa Book Festival. #GoaBookFestival2026 #BookSigning #MeetTheAuthor #TripleNegative #AartiPathak #IndianAuthors #BookLovers #GarudaPrakashan

Impermanence reminds us: even the darkest moments pass. In Triple Negative: A Tale of Love, Faith, and Surrender, Aarti Pathak shares a deeply moving journey of resilience, devotion, and inner strength—where faith becomes the anchor and surrender becomes power. A story that will touch your heart, steady your spirit, and remind you to rise, no matter the odds. 📖 Book: Triple Negative: A Tale of Love, Faith, and Surrender ✍️ Author: @aarti_kpathak 👉 Buy your copy: Garudalife - garudalife.in/triple-negativ… Amazon - amzn.in/d/4rz3VUD #TripleNegative #AartiPathak #FaithAndResilience #LoveAndSurrender #InspirationalReads #IndianAuthors #GarudaPublications #BookLovers

📚 Book Signing Invitation ✨ Join us for a special book signing session with Aarti Pathak, author of Triple Negative — a tale of love, faith, and surrender. Meet the author, get your copy signed, and experience a heartfelt literary evening celebrating stories of strength, hope, and resilience. 📍 Bahrisons Booksellers, Park Street, Kolkata 🗓 24 January 2026 ⏰ 5:00 PM – 6:00 PM We look forward to welcoming all book lovers and readers! @Bahrisons_books @aarti_kpathak #BookSigning #TripleNegative #AartiPathak #AuthorMeet #BookLovers #ReadersCommunity #LiteraryEvent #IndianAuthors #BookLaunch #FaithHopeLove #BahrisonsBooksellers #KolkataEvents #ParkStreet #GarudaBooks #GarudaLife #BooksThatInspire #MustRead

Today, I got to ring my bell! Officially, I am in remission and cancer free #breastcancer #cancersucks #ringthebell #cancerfighter #Cancersurvivor #triplenegative #cancer

Death’s lesson: We will all face death one day — but we don’t have to live in its shadow until that day comes. ❤️ Triple Negative: A Tale of Love, Faith, and Surrender by @aarti_kpathak is a deeply moving story of courage, resilience, and hope in the face of life’s toughest trials. 📘 Buy your copy here: Garudalife - garudalife.in/triple-negativ… Amazon - amzn.in/d/58GjGmM #TripleNegative #AartiPathak #LoveFaithSurrender #Hope #HealingThroughStories #BookRecommendation #MustRead

Grace under fire. When the body breaks, the spirit rises. Triple Negative: A Tale of Love, Faith, and Surrender by @aarti_kpathak A deeply moving story of resilience, hope, and unwavering faith in the face of life’s toughest trials. 📖 Grab your copy now: Garudalife - garudalife.in/triple-negativ… Amazon - amzn.in/d/cVf8qQV #TripleNegative #AartiPathak #GraceUnderFire #FaithAndStrength #Resilience #Hope #TrueStory #IndianAuthors #BookLovers #MustRead #GarudaPrakashan