24 Feb 2025
This past month has seen the publication of a couple of new helpful papers providing further insights into the thorny issue of #MultipleTesting in trials 1/7
#MethodologyMonday #112
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5 Aug 2024
A common issue that we come up against in clinical trials is #MultipleTesting 1/7 #MethodologyMonday #99
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17 Apr 2024
In #hydrological sciences at #EGU24, inflationary use of hypothesis tests with no adjustment for #multipletesting persists. Check out our 2020 paper for suitable adjustment methods in a #spatiotemporal setting: doi.org/10.1007/s10651-020-0… @Ellis_Unit_Jena
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20 Jan 2022
This week on #GenomicsBootCamp you can find a basic theoretical introduction to genome-wide association studies #GWAS
#genetics #genomics #multipleTesting #populationStructure
youtu.be/7iarFfxYxQc
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13 Dec 2021
#BenjaminiHochbergMultipleTesting-1
[#NobleMultipleTesting
#RobertsonWasonBretz
#ScientificMethod
#Statistics]
"Journal of the Royal Statistical Society B 57(1), pp. 289-300 (1995)
Controlling the False Discovery Rate: a Practical and Powerful Approach to #MultipleTesting
>
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8 Sep 2021
Another super amazing workshop with outstanding speakers organised by David Robertson of the @MRC_BSU!
Looking forward to it!
#multipletesting
#Statistics
#workshop
#DataScience
23 Aug 2021
Registration is now open for our FREE online workshop on current and future trends in multiple hypothesis testing, on Tues 21st Sept.
eventbrite.co.uk/e/workshop-…
#clinicaltrials #biostatistics #DataScience
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20 Aug 2020
Updated version (v2) of our commentary paper "Pitfalls in re-analysis of observational omics studies: a post-mortem of the human pathology atlas" is now online on bioRxiv biorxiv.org/content/10.1101/…. #FalsePositives, #DataDredging, no #MultipleTesting, #confounding, #PathologyAtlas
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7 Jul 2020
Just one day to go till @tonyajhwhite will speak on #multipletesting correction with her insightful story on how to correct previous science. Definitely not to be missed! Please contact @asch3tti or @elisabetbl to attend.
30 Jun 2020
Erasmus #ReproducibiliTea journal club with @rdam_riots!
July 8th, h.14:00 CEST: @tonyajhwhite, wrong FDR formula, and the challenges of correcting the scientific record.
Contact @asch3tti or @elisabetbl for the Zoom link!
Details here:
openscience-rotterdam.com/20…
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12 May 2020
Working with #spatiotemporal #datacubes and performing pixel-wise tests? Some cautionary remarks of, and solutions for the #MultipleTesting issue were developed in a PhD project by José Cortés. @UniJena @MPI_BGC joint research school. Super work Jose! link.springer.com/article/10…
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29 Apr 2020
3 trials of #remdesivir “reported” today, two small studies and one large #RCT. Since the same hypothesis was tested in three different trials, what statistical method was (should have been) used to correct for multiple testing? Anyone? #stats #multipletesting
29 Apr 2020
Am I reading this correctly: on the endpoint the trial was designed to measure remdesivir showed no benefit over comparator, but if you look at the data any way you want, there is a new hypothesis about potential benefits if given earlier. #RCT #researchEthics #COVID19
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18 Mar 2020
Check our new paper “Pitfalls in re-analysis of #observational #omics studies: a post-mortem of the human #PathologyAtlas”. Many #FalsePositives expected, binarization of #GeneExpression, #DataDredging, no #MultipleTesting & #confounding biorxiv.org/content/10.1101/…
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17 Dec 2019
But what about a PFS benefit? #MRCIX showed PFS benefit, but only for the first 4 mos. with Zometa vs Clodronate. In #AMG162 Denosumab improved PFS vs Zometa only in a subgroup and only assessed locally. #MultipleTesting @kaufman_MMdoc #mmsm
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9 Dec 2019
Excellent point. Are #cancer #antibody #drugs that act on the same target actually different? Shouldn't all these (bio)similar trials be analysed as biological replicates, rather than giving a reward to the lucky random outlier? #greenjellybeanproblem again #multipletesting
This tweet is unavailable
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12 Mar 2019
Greg Francis from @LifeAtPurdue has just opened our #OpenScience Conference in #Trier with his talk "Rethinking #multipletesting for #replication and #preregistration".
Further information: conferences.leibniz-psycholo… …
#zpidevents @TrierUni
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5 Nov 2018
Hey #sciencetwitter!
I argue that tylervigen.com/spurious-corr… illustrates the problem of #falsediscovery in #multipletesting. More relevant for "#correlation doesn't mean #causation" would be understanding of confounding variables in real and reproducible correlations.
Opinions?
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25 Jun 2018
Somewhere in the world, a guy has thousands of octopus predicting #worldCup2018 soccer games. And soon he will announce the new #PaulTheOctopus, with a successful set of predictions...
#Bonferroni #MultipleTesting
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20 Jun 2018
19 Jun 2018
For those interested in multiple hypothesis testing, @nomadj1s , @davidmolitor, and I added support for clustered standard errors to our @Stata command, wyoung. Type "ssc install wyoung, replace" at Stata prompt to install the latest version.
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13 Jun 2017
DDAVP if eGFR<20 at our centre. Local policy, personally not seen convincing evidence of benefit.This 📝 doesn't change that
#MultipleTesting
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