We're a lab working to understand and improve the immune response to cancer at @muschollings

Joined June 2014
1 Photos and videos
Our lab member Eric Czech will present this work at #biodata18 on Saturday. The source code is available at github.com/hammerlab/cytokit. If you're interested in GPU-accelerated open source software for the analysis of multiplex tissue imaging data, we'd appreciate your feedback!
Cytokit: A single-cell analysis toolkit for high dimensional fluorescent microscopy imaging biorxiv.org/cgi/content/shor… #bioRxiv
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Hammer Lab retweeted
13 Jun 2018
This is what we have been working on at @hammer_lab for the last few months: Human Primary T Cells: A Practical Guide - Live document: docs.google.com/document/d/1… - Code/data: github.com/hammerlab/t-cell-… - Protocols: protocols.io/view/human-prim… cc: @PINPINPINN @Chrystal_Paulos

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11 Jan 2018
A few of our former lab members have formed a new lab to continue their work on open source software for neoantigen vaccines. Go follow them at @OpenVax! x.com/iskander/status/951198…

It's still a work in progress, but I just made a website for the new @openvax lab at Mount Sinai: openvax.org/. Focus: machine learning applied to immunology, neoantigens, personalized cancer vaccines.
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10 Jan 2018
New preprint! Prohlatype: A Probabilistic Framework for HLA Typing by @leonidrozenberg biorxiv.org/content/early/20…

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Hammer Lab retweeted
We just released MHCflurry 1.0, our MHC I ligand prediction package. 20% more alleles, over 10X faster, docs, and an accuracy boost. Happy predicting! bit.ly/2p9sT2M @hammer_lab

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11 Dec 2017
Introducing spark-bam, a foundational library that enables the distributed processing of aligned reads with @ApacheSpark, by @RunsAsCoded: hammerlab.org/2017/12/11/int…

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New preprint from @smondet on how our lab uses @OCamlLang to manage complex bioinformatics workflows on cloud, Hadoop, and HPC environments x.com/biorxiv_bioinfo/status…

Bioinformatics Workflow Management With The Wobidisco Ecosystem biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
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14 Aug 2017
We've posted a preprint that describes the open source software powering the neoantigen vaccine trial described at clinicaltrials.gov/ct2/show/… x.com/iskander/status/895753…

New preprint: "Computational pipeline for the PGV-001 neoantigen vaccine trial". biorxiv.org/content/early/20…
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10 Aug 2017
Replying to @timodonnell
Read the preprint, "MHCflurry: open-source class I MHC binding affinity prediction”, at biorxiv.org/content/early/20…

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10 Aug 2017
Benchmarking MHCflurry, take 2 by @timodonnell: hammerlab.org/2017/08/10/ben…

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26 Jun 2017
Introducing SurvivalStan, with an epic introduction to Bayesian survival analysis with @mcmc_stan, by @jackiburos: hammerlab.org/2017/06/26/int…

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23 Jun 2017
A broad but shallow review of informatics in cancer immunotherapy: biorxiv.org/content/early/20…

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We use Vaxrank in our clinical trial that’s actively recruiting patients; for more on the trial see explorer.opentrials.net/tria…
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New preprint! Vaxrank: A Computational Tool For Designing Personalized Cancer Vaccines biorxiv.org/content/early/20…

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We’re quite proud of this paper! One reviewer: “It sets the bar for ... biomarker analyses in patients treated with checkpoint inhibitors” x.com/PLOSMedicine/status/87…

Tumor and immune features associated w/ clinical response to checkpioint blockade therapy in urothelial #Cancer journals.plos.org/plosmedici…
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