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Heard_Lab @heard_lab
Joined September 2018
  • Tweets 159
  • Following 294
  • Followers 2,215
5 Photos and videos
Heard_Lab retweeted
Cornelius Gross@Cornhelix
28 Jan 2025
Do you have ambitious plans to study the molecular mechanisms of environmental adaptation in mammalian model systems? Join EMBL Rome as an independent group leader: generous core funding & benefits, top-level students & core facilities. embl.wd103.myworkdayjobs.com…
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Heard_Lab retweeted
Edda Schulz@EddaGSchulz
11 Oct 2024
📢 New preprint from the lab! CRISPR-screening wizard 🧙 🧬 @TSchwammle figured out how different signals 🚦 are integrated at the Xist locus. See his tweetorial below. biorxiv.org/cgi/content/shor…

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Heard_Lab retweeted
EMBL@embl
9 Oct 2024
EMBL congratulates David Baker, Demis Hassabis, and John Jumper on the 2024 #NobelPrize in Chemistry for their seminal discoveries and developments on protein structures. @nobelprize @demishassabis @GoogleDeepMind #chemnobel
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Heard_Lab retweeted
Elphege Nora Lab at UCSF@ElphegeNoraLab
5 Oct 2024
First preprint from the lab 🚨 How can enhancers regulate target promoters across vast genomic distances, and what is the role of cohesin loop extrusion in the process? biorxiv.org/content/10.1101/… (1)

Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function

Enhancers are critical genetic elements controlling transcription from promoters, but the mechanisms by which they convey regulatory information across large genomic distances remain elusive. Here,...

biorxiv.org
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Heard_Lab retweeted
Institut Curie@institut_curie
30 Aug 2024
Le Dr @ClaireRougeulle prend ses fonctions en tant que directrice du Centre de recherche à compter de ce 1er septembre 2024. Sa nomination par le Directoire de l’Institut Curie le 3 juillet 2024, marque le début d’un mandat de 5 ans. ➡️ curie.fr/actualite/instituti…
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Heard_Lab retweeted
Flora Vincent@vincentflora
18 Aug 2024
Really amazing to see how non traditional model organisms are picking up. Here at @janeliaconf and soon… our @embl @EMBO symposium on the « Wild Frontiers of Model Organisms » ! Check it out!! => embl.org/about/info/course-a… @Dey_Gautam @mwdorr @NicoleDubilier Susana Coelho

Wild frontiers of model organisms

embl.org
Janelia Conferences@janeliaconf
15 Aug 2024
This meeting @HHMIJanelia will bring together researchers to share challenges and successes in the development of new genetic tools for a broad range of non-traditional model organisms and biological problems. Learn more apply by Oct. 29 @ janelia.news/NMS25 @HHMINews @TessaMontague
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Heard_Lab retweeted
Claire Rougeulle@CRougeulle
9 Jul 2024
Congratulations to you both
Institut Curie@institut_curie
9 Jul 2024
👏 Congrats to Drs Allison Bardin and Valérie Borde, team leaders at Institut Curie Research Center, selected for their outstanding scientific contributions to join the @EMBO Membership. ➡️ institut-curie.org/news/awar…
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Heard_Lab retweeted
EMBL@embl
9 Jul 2024
Congratulations, Nick Goldman and Mikhail Savitski! Both EMBL group leaders have been elected as EMBO members for their research excellence. They'll be joined by Oliver Billker, a member of the @NordicEMBL Partnership, and many EMBL alumni. embl.org/news/awards-honours…
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Heard_Lab retweeted
Collège de France
@cdf1530
7 Jun 2024
#Science #Biologie "L’interface organisme-environnement" 📌 Colloque en anglais organisé par la Pr Edith Heard, titulaire de la chaire #Épigénétique et mémoire cellulaire ⏰ Les 11 et 12 juin 2024 👉 college-de-france.fr/fr/agen…
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Heard_Lab@heard_lab
26 May 2024
Join us at this year’s meeting on epigenetics at the interface of the organism and its environment, at the College de France on June 11-12th @cdf1530. No registration needed and a fantastic line up of speakers! college-de-france.fr/fr/agen…
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Heard_Lab retweeted
Jamie Hackett@hackettlab
9 May 2024
Massive congrats to @CristinaPolica4 who led this study magnificently over many years. An epic tour de force and a wonderful colleague👏👏 Huge shout out also to co-authors @munafomarzia @SteliosTsagkris #ValentinaCarlini, and all lab members who made this happen🙏
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Heard_Lab retweeted
Sara Formichetti@SaraSciFormi
7 May 2024
2nd work from my PhD is out!🤩Mammalian Ogt (enzyme of reversible intracellular glycosylation aka O-GlcNAc) is an X-linked essential gene. We use a complementary approach to the direct removal of O-GlcNAc (the other paper) to study the role of this PTM in embryos: 1/9🧵
biorxiv_devbio@biorxiv_devbio
28 Apr 2024
Genetic gradual reduction of OGT activity unveils the essential role of O-GlcNAc in the mouse embryo biorxiv.org/cgi/content/shor… #biorxiv_devbio
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Heard_Lab@heard_lab
4 May 2024
Our one and only @HauthAntonia defended her PhD this week: Congratulations Dr. Hauth 🥳🤩🥳🤩 First PhD of the Heard lab @embl - we are all very proud of you 👏👏👏
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Heard_Lab retweeted
Jan Żylicz@JZylicz
22 Mar 2024
Our first pre-print from the lab in collaboration with @Scwin2 T.Moritz @EpiQMAx. @KarlienVN &Co found that metabolic rewiring in early human development aids trophoblast lineage induction via acetylation regulation. Check out:shorturl.at/abgGV @reNEW_Global @Metabolcenter

Metabolic rewiring underpins human trophoblast induction

Development is driven by a sequence of molecularly interconnected transcriptional, epigenetic, and metabolic changes. Specific metabolites, like α-ketoglutarate (αKG), function as signalling molecu...

researchsquare.com
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Heard_Lab retweeted
Molecular Cell@MolecularCell
7 Mar 2024
Chromatin gene-gene loops support the cross-regulation of genes with related function dlvr.it/T3mTjg
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Are you a female scientist in Africa looking for an exciting research placement opportunity?👩‍🔬🔬 Don't miss out on the @UNESCO-@EMBL Residency in Infection Biology! Apply before 31 March, and take your research to the next level! 👉 unesco.org/en/articles/unesc…
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Heard_Lab@heard_lab
26 Feb 2024
💥💥New pre-print alert 💥💥 👇 Xist RNA continues to fascinate: in our latest work we show that increased or decreased levels of Xist RNA directly control the expression levels of genes that escape X-inactivation 1/3 biorxiv.org/content/10.1101/…

Escape from X inactivation is directly modulated by levels of Xist non-coding RNA

In placental females, one copy of the two X chromosomes is largely silenced during a narrow developmental time window, in a process mediated by the non-coding RNA Xist [1][1]. Here, we demonstrate...

biorxiv.org
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Heard_Lab@heard_lab
26 Feb 2024
Xist’s silencing function also impacts the 3D structure of the inactive X chromosome leading to loss of TAD-like structures in a post developmental context 3/3
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Heard_Lab@heard_lab
26 Feb 2024
Congratulations to all involved - this is the result of a great collaboration 🤩 @OliverStegle @odom_lab @zauggj @HowardYChang
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