Partner at @Pillar_VC šŸš€ ISTJ 🐢

Joined February 2009
1,101 Photos and videos
Sarah Hodges retweeted
Today we're publicly launching @OrmoniBio. The peptide industrial revolution has begun. 🧵
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Sarah Hodges retweeted
First met @jerallaire and @psneville when we hosted the blockchain summit in 2017. We were lucky to be investors in @circle and seed investors in @catena_labs in 2022. Sean and company are the perfect team at the perfect time to be attacking this problem.
Replying to @catena_labs
If you're running agents that touch money, or are about to, come build with us. Private Access is open at catena.com
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Sarah Hodges retweeted
In the month of March we raise awareness for this debilitating disease, and as we wrap up I felt it appropriate to write a short piece to highlight how proud we are to get to work with Ashley Abel, Ph.D. and the team at Metri Bio. Read more here: pillar.vc/investing/immovabl…
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Sarah Hodges retweeted
Start a company in AI for Science. The Encode: AI for Science fellowship offers a year of freedom to build what matters -- salary, 100k GBP of compute, and partnership with the top scientists in the UK. No equity or fees, it's a fully funded fellowship! Apply by March 28
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Sarah Hodges retweeted
Freedom to Build What Matters The first glimmers of AGI are here. Whatever you can dream of, you can build. The efforts of a single individual have never mattered more. A single person, an idea, and a late night in the lab might be what changes a field. And yet the outputs of such extraordinary power have mostly been disappointing. We are using the most important technology in history to create addictive short-form video, AI girlfriends, and better ad targeting. Now is the time to do the work that will define this era. We can cure disease, feed a continent, or make humanity multi-planetary. What you choose to work on now may be the most consequential decision of your career. We built the Encode: AI for Science Fellowship for people who feel that weight. One year of salary, plenty of compute, and direct access to frontier labs, data, and domain experts across biomaterials, atmospheric science, neuromodulation, robotics, and more. No equity, no strings attached — just the freedom to explore. We've partnered with ARIA and the UK's leading research universities to make it possible. Applications close March 28th.
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What will you build when you have the freedom to build what matters? Incredible things are happening in Boston—in labs, warehouses, and basements. The weird and the serious are moving fast. The window is open. We're helping kick off the Massachusetts AI Coalition with a launch event on creativity, cognitive science, and solving hard problems. Speakers from Harvard, MIT, Tufts, Oscillator, Rowan Scientific, Glia AI, and WHOOP. Link to register šŸ‘‡
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Sarah Hodges retweeted
Today we're announcing Day AI's $20M Series A led by @sequoia, and that we're now generally available. We've spent 18 months building what we believe is the Cursor of CRM. Here's what that means 🧵
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Sarah Hodges retweeted
Science is our calling. It's January 2026 and in some vague but very real sense, the glimmers of AGI are here. You can toss off a goal and an AI agent will happily chug away. We can do anything. But what is worthy of doing? We're not here for the AI romantic companions, the vibes reels, and the marketing outbound. If we can do anything, we're going to do science. Science is how we build the world we actually want. It's how we will solve the problems we'll be proud to tell our children we dedicated ourselves to. We want to hear from the people pushing AI to the limits in pursuit of science. The window is open. The weird and the serious are moving fast. Incredible things are happening in labs, warehouses, and basements. Over the next couple of weeks, we’ll be gathering in three cities—San Francisco, London, and Boston. We’ll have some visionary speakers joining us. Link below.
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There’s been a lot of talk about whether Boston is still a great place to build (we're bullish) — but talk doesn’t build companies. We’re moving into 30k sq ft this fall. How should we use it to actually help founders? Ideas welcome.
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Sarah Hodges retweeted
10 years ago, we started @pillar_vc with a simple belief: Treat founders the way we would want to be treated and good things will happen. A decade later, the data says it works. 🧵
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Sarah Hodges retweeted

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Sarah Hodges retweeted
18 Dec 2025
Super excited to announce Edison. I worked with Sam, Andrew, and team from the beginning to help form FutureHouse. When it came time to spinout Edison, I both invested and jumped in to build alongside them. I couldn’t be prouder of the progress we have made. Join us!
Science is too slow. At Edison, we are integrating AI Scientists into the full stack of research, from basic discovery to clinical trials. We want cures for all diseases by mid-century. We have raised a $70M seed to get started. Join us. We need cracked software engineers who want to work on finding cures rather than selling ads and generating slop. If you’re reading this, you’re probably a candidate. We need brilliant AI researchers who want to figure out how AI will accelerate real-world science. We need scientists and researchers with deep expertise in biology, biotech, and pharma who want to figure out how to integrate AI deeply into scientific workflows, from ideation to experimentation, and how to measure success or failure. We need extraordinarily talented generalist operators across BD, sales, product management, and partnerships who can focus on getting our tools into the hands of pharmaceutical companies. If any of these roles sound like you, get in touch. We are also expanding access to our platform. Our goal is to accelerate science writ large. To that end, we will continue to give academics and students 650 credits/mo indefinitely. I can’t promise we’ll keep this up forever, but we will try. Kosmos will still cost 200 credits, and the other agents (Analysis, Literature, etc.) will cost 1 or 2 credits. All paid users will have access to our regular agents, like our Analysis agent, Literature agent, and so on, for free via the UI. API access will still be paid, and users without a paid subscription will continue to get 10 credits per month for those agents. Our $200/mo subscription for 650 credits/mo is staying in place for now, but might be phased out at our next major product update. Along the lines of accelerating science, we’re also doing a major release of PaperQA today, our flagship open source literature agent, as part of our commitment to open science. In the short run, expect major improvements to Kosmos, including the ability to automatically access data, the ability to steer its exploration, and the ability to converse directly with its world model. In the long run, expect exponentially increasing rates of scientific discoveries, in biology and elsewhere. Our round is led by Triatomic Capital, Spark Capital, and a major US institutional biotech investor. We are also joined in this round by existing investors Pillar VC and Susa Ventures, two exceptional early-stage funds who backed us at founding, along with Striker Venture Partners, Hawktail VC, Olive VC, and a host of exceptional angels that includes famous AI researchers, the CEOs of multiple frontier AI labs, and leadership of major biotech and pharma companies.
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Sarah Hodges retweeted
17 Dec 2025
Congrats to Encode: AI for Science fellow, @ayushnoori on this huge release!
I’m excited to share PROTON, a pre-trained relational transformer for neurology. 🧠 PROTON generates testable neurological hypotheses, which we evaluated across: 🧬 Parkinson’s disease: genome-wide in vitro and in vivo screens 🧫 Bipolar disorder: patient-derived brain organoids šŸ„ Alzheimer’s disease: 610,524 patients tracked across 7 years By pairing AI with real-world experiments, PROTON defines a path for AI-driven discovery in neurological disease. Paper: arxiv.org/abs/2512.13724 Website: protonmodel.ai Code: github.com/mims-harvard/PROT… Model: huggingface.co/mims-harvard/… Learn more below šŸ‘‡šŸ½ [1/8]
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Sarah Hodges retweeted
16 Dec 2025
Introducing Latent-X2 — AI-generated antibodies with drug-like developability and low immunogenicity in human panels, zero-shot. Technical report: tinyurl.com/latent-X2-report Blog: latentlabs.com/latent-x2 Apply for access: partnerships@latentlabs.com
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Sarah Hodges retweeted
Today, we’re pushing a major update to Edison Analysis, our data analysis agent, which is tuned for scientific research and SOTA across data analysis benchmarks. In contrast to Kosmos, which runs for 6-12 hours and produces tens of thousands of lines of code, Edison Analysis runs for seconds to minutes and is best for specific, well-defined computational tasks. It is available both on our platform under the Analysis tab, and via API, and costs only one credit per run, so it is available to users on both free and paid tiers. Edison Analysis is a modified version of the data analysis agent Kosmos uses in its trajectories. Try it out! One of the most important improvements over our previous data analysis agents has been the addition of a specialized data retrieval tool. Edison Analysis can either use this tool to access data, or can pull data down directly via API. To evaluate this tool, we ranked the most commonly used public data repositories across recent papers from BioRxiv, and created a new benchmark that measures the ability of a language agent system to retrieve raw data from those sources. Edison Analysis gets 71% on this benchmark, and we’ll be working to increase this over time. You can read more about our benchmarks in the our blog post, link below. Some features worth highlighting: 1. Edison Analysis produces a report on the analysis it runs, along with a Jupyter notebook that you can download to reproduce the analysis yourself. Every figure it produces is linked back to the specific lines of code used to produce the figure, to make it easy to reproduce. 2. It works well with both Python and R. 3. One of the best uses for Edison Analysis is to use it to retrieve datasets that you can then analyze with Kosmos. We have a bunch of major improvements to Edison Analysis coming in the next few months that we’re excited to share. In the meantime, congratulations to the team, especially @ludomitch, @jonmlaurent, @cvi94 , @alexjandonian, and many more.
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Sarah Hodges retweeted
Replying to @sama
Thanks!! Anyone who is interested can try Kosmos for themselves here: platform.edisonscientific.co… All possible in large part due to the amazing work you guys have been doing at OpenAI. Keep it up, and the next few years are going to be awesome.
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