Anxiety disorders, OCD, Schizophrenia. Halifax, Aarhus, Munich. Personal account, all views are mine.

Joined December 2011
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Pinned Tweet
We would like to share with you our recently published article “Identification of shared and differentiating genetic risk for autism spectrum disorder, attention deficit hyperactivity disorder, and case subgroups.” rdcu.be/cWmMA… Details below.

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Manuel Mattheisen retweeted
5 Dec 2022
Checkout our new preprint of a GWAS study of self- and parent-reported obsessive-compulsive symtoms (OCS) in ~34k EUR individuals from 7 population-based (twin-)cohorts. doi.org/10.1101/2022.11.30.2… 1/8
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Manuel Mattheisen retweeted
12 Oct 2022
We are pleased to announce that our height GWAS: A Saturated Map of Common Genetic Variants Associated with Human Height is published in @Nature today! This is a fantastic effort involving >600 GIANT consortium investigators and @23andMe.
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We would like to share with you our recently published article “Identification of shared and differentiating genetic risk for autism spectrum disorder, attention deficit hyperactivity disorder, and case subgroups.” rdcu.be/cWmMA… Details below.

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10/11 Moreover, they suggest that studies such as iPSYCH, i.e., studies with longitudinal phenotypes across diagnostic boundaries, are needed to disentangle the complex relationship between and across mental illnesses.
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11/11 Summarizing, our results provide novel insights into the biological foundation for developing just one or both conditions and for driving psychopathology discriminatively towards ADHD or ASD.
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Manuel Mattheisen retweeted
Three internships open at the @SGDP Centre - do apply and circulate to relevant groups. @BlackInGenetics @BlackInNeuro
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We would like to share with you our new preprint “Identification of shared and differentiating genetic risk for autism spectrum disorder, attention deficit hyperactivity disorder and case subgroups”. medrxiv.org/cgi/content/shor… Some details below.

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10/10 Summarizing, our results provide novel insights into the biological foundation for developing just one or both of the disorders and for driving the psychopathology discriminatively towards either ADHD or ASD.
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9/10 Moreover, they suggest that studies such as iPSYCH, i.e. studies with longitudinal phenotypes across diagnostic boundaries, are needed to disentangle the complex relationship between and across mental illnesses.
8/10 Our observations are consistent with the notion that the genetics differentiating the two disorders may be driven primarily by common variants and more extensively for cases diagnosed with ID compared to those without a diagnose of ID.
7/10 Case subgroups defined by comorbidity or lack thereof with ADHD and ASD show distinctive patterns of genetic association with other traits when compared to the ASD-only and ADHD-only subgroups.
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