Nate Crownlands put together an absolutely remarkable achievement that will materially speed up the pace in which we can solve brain diseases. I cannot articulate enough how big I believe this will be. (This is not paid, I fucking love and believe in Nate so much)

I had heard maybe ~20 pitches on building AI agents to accomplish XYZ task and not a single one of them came close to the level of thoughtfulness and focus that Markie was able to articulate. Don't know her super well, but I do know this round is well deserved.

.@bryceehunt

Being serious: Does this immigration policy mean that if I want to marry my Canadian girlfriend, she will have to leave the country for up to two years in order for her to become a citizen? Am I missing something?

What’s remarkable about Adam and Dean is they not only have built a remarkable business and product… But they did so in *the absolute hardest customer cohort imaginable* Absolute killers.

I've spent an enormous amount of time turning my entire business into something I can type into the command line and my business life has basically become a video game.

My buddy Josh is 31 with a biological age of 16. People IRL constantly assume he is 21-22 years old. @bryan_johnson he's coming for your crown.

Measure 10x, cut once.

I still find it mind blowing this video was made in 2014

Any time my agent uses an MCP instead of an API it messes it up 60 % of the time MCP is the dumbest most unnecessary invention of all time why do people not use APIs I do not understand

Set up a digital ocean droplet, install coding agent (Droid/CC/Codex) on it, then connect to it via Termius on your phone. Install GitHub CLI, AWS/GCP CLI, add Postgres credentials to the agents md file and the CLI tool you use to deploy sites (Netlify/Vercel).

Programming with Opus 4.5 is the most fun I’ve had since the iOS 8 jailbreak in 2014

One of the coolest things about growing up is watching some of your friends shape the world.

One thing I haven't heard in Silicon Valley is most tasks don't benefit from additional intelligence beyond a certain point. The dropping cost of intelligence will matter way more than maximum model capabilities in the medium term.

It’s quite sad to watch the degradation of most of our elite institutions (universities, Mag 7, venture funds) from artisan-run boutiques into daycare factories for hyper-optimizer nerds living in extended adolescence.

Probably my favorite thing I’ve learned from Hormozi was his explanation of the difference between working with an expert vs an amateur. The difference between an expert and an amateur is simply the amount of reactive instruction required by you in order to achieve a certain outcome. Experts are people for whom you can provide very little initial context or correction and they’ll be able create the scaffolding for something spectacular. Amateurs need hand holding and extreme accountability mechanisms, all the time. It genuinely takes more time to instruct somebody to do something correct than it does to do it oneself. I know a Ben Horowitz tweet is going viral right now for saying “Hire A players” is super obvious, but I genuinely believe that the power law for talent is real improvement on the morale of the founders (and rest of the management team) from working with exceptional talent is genuinely hard to overstate. I’ve only heard very few people talk about the cognitive relief that you get when you can finally work with a killer VP (expert). There is, without exaggeration, a genuine 100x difference in your own stress levels between somebody who you trust 70% vs. 110% to execute a function.

Ryan fixed my Google ad account last year when nobody else could. He did not charge me. He did not know me. He deserves every single penny.

Seeing a lot of comments on this and wanted to put my guess in on what’s going on: CalAI Cohort of apps do 3.6M/mo in revenue — that’s real. That said, they’re putting a lot of that money into growth, so my guess is ~15% net margins. That means ~$500K/mo in take home, pre-tax. ~$300K/mo take home, post tax (California LLC Income Tax). Split between 3 (I think) co-founders =~$100K/mo each. Despite building an illiquid net worth of high 8 figures, maybe low 9 figures each, but I’d be shocked if they had more than a low 7 figure liquid net worth, each. Organic acquisition $1.75K/ticket = Only 180 people need to sign up for them to make as much money this month from this as they do from they do from the several hundred thousand people that use CalAI. It makes sense for them to want a bit more liquidity. And there’s no better model than info for short term liquidity. Additionally, @blakeandersonw has been talking about teaching people how to do what he’s done for years. This isn’t out of character for him to want to share what he’s made. Why not make money from it / attract the people who are most willing to actually commit to making a change?

I have been incredibly fortunate to be able to work with this team. @varungupta @tonsing and the whole Caffeinated Crew are world class. I could not ask for better partners.

Grateful to be alive, for my friends, my partners, my family, and for the opportunity to pursue what I love daily.