Assistant Professor at the @UofT @DonnellyCentre and @MoGen_Grad. Large-scale human genetics and massively parallel screens to study disease!

Joined March 2009
112 Photos and videos
‼️ New preprint from the Morris Lab at the @DonnellyCentre! This is our latest work in GWAS‑to‑function to study the genetic determinants of human bone formation and osteoporosis! 🧬 ➡️ 🦴 biorxiv.org/content/10.64898…

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Our lab continues to grow! We have just recruited three talented graduate students to expand our efforts in studying the noncoding genome 🧐 Please give a warm welcome to Mike (@Mike__Kazemi), Hannah, and Javad (@mjkahlani)! 🥳 morris-lab.org/team
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For no reason in particular, I would like to remind everyone that we have a Functional Genomics faculty position opening at the @DonnellyCentre at the University of Toronto (in Canada 🇨🇦) 👀 #ASHG24 jobs.utoronto.ca/job/Toronto…
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John Morris retweeted
The @DonnellyCentre is now #hiring an Assistant Professor in functional #genomics. #UofT Deadline to apply is January 16. Learn more 👉 uoft.me/DCAssistantProfessor
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John Morris retweeted
📢 We’re hiring! The Department of Molecular Genetics is looking for an Assistant Professor in Molecular Biology & Genetics at the @DonnellyCentre. 🔗 Apply here: uoft.me/MoGenHire 🗓️ Closing date: Dec 19. Please share and encourage great candidates to apply!
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21 Oct 2024
Another tenure-track assistant professor position at the University of Toronto! This is for the Department of Molecular Genetics (a great dept. in my unbiased opinion 😉) and your lab would be at the world-class @DonnellyCentre! Apply by Dec. 19! jobs.utoronto.ca/job/Toronto…
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It's faculty job application season so why not apply to the University of Toronto and be my colleague at the @DonnellyCentre! We have a tenure-track opening to do functional genomics research at our world-class institute. Check it out and apply by Jan. 16! jobs.utoronto.ca/job/Toronto…
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John Morris retweeted
Excited to share the white paper for the IGVF Consortium, supported by @genome_gov Deciphering the impact of genomic variation on function rdcu.be/dSZdm

Understanding the function of an entire genome is no easy task! Most genes likely have more than one function. To understand the functional effects of genomic variation, NHGRI launched a consortium called Impact of Genomic Variation on Function (IGVF). genome.gov/news/IGVF
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Dear European friends, I will be in Belgium in March to talk about the exciting work we are now doing at @UofT on massively parallel genome engineering to study GWAS loci!
First #RNGS25 speakers announced! The topics for this 3-day conference are: 🔸innovative approaches in #sequencing 🔸#multiomics 🔸#3DGenomics 🔸#epigenomics 🔸large scale sequencing 🔸and the impact of #ML & #AI on NGS 🗓️19-21 March 2025, Antwerp, BE 🔗 vibbio.tech/47fK6c1
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John Morris retweeted
The @DonnellyCentre is now accepting applications for the Charles H. Best Postdoctoral #Fellowship! Apply to join one of the top interdisciplinary institutions in the world for tackling big questions in medicine and health. #postdocposition Learn more 👉 bit.ly/CharlesBestFellowship
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John Morris retweeted
The @DonnellyCentre welcomes a new faculty member, Dr. Aleksandrina Goeva! 🎉 Dr. Goeva joins our experts in computational #biology as an Assistant Professor with a focus on analyzing single-cell and spatial transcriptomics data. #UofT Learn more 👉 uoft.me/AleksGoeva
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31 May 2024
Morris Lab n = 2 🥳 Huge welcome to Marinella Gebbia, who has joined as our lab manager! She comes to us from @FPRoth's lab and brings a wealth of experience in deep mutational scanning. We are growing! morris-lab.squarespace.com/t…
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John Morris retweeted
At Biology of Genomes #bog24? Don't miss @wenweiliang's talk TONIGHT on Transcriptome-scale screens w/ RNA-targeting CRISPRs — joint work from her & @drsimonmueller in our lab. Exciting new approaches to identify functional noncoding RNAs across the human transcriptome! 🕵️✂️
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18 Apr 2024
This is amazing! I'd say it's a great time to come to Canada for grad school or your postdoc 😉
17 Apr 2024
Researchers in Canada got most of what they were hoping for in the country’s 2024 federal budget, with a big boost in postgraduate pay and more funding for research and scientific infrastructure go.nature.com/4azQ8Ft
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The Morris Lab at the @DonnellyCentre for Cellular and Biomolecular Research and the University of Toronto is officially open for business, and the lab website is live! Check it out for info on our research and how you can join: morris-lab.org
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John Morris retweeted
Our new preprint describes “CROPseq-multi”: a versatile solution for multiplexed perturbation and decoding in pooled CRISPR screens doi.org/10.1101/2024.03.17.5… Reagents on Addgene: addgene.org/browse/article/2…
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So happy to share this work from the @tuuliel_lab led by @JuliaDiumenge! It builds on the regulatory networks we discovered by inhibiting enhancers identified from noncoding GWAS variants, finding non-monotonic responses 🧐🧐🧐
We know the importance of subtle gene dosage variation, and yet the main tool of molbio is gene KO/KD. In our new preprint, @JuliaDiumenge introduced subtle modulations of transcription factor dosage by CRISPRi/a, and quantified responses by scRNA-seq. 1/ biorxiv.org/content/10.1101/…
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John Morris retweeted
Excited to share our review paper in Cell! With @SashaGusevPosts @s_ramach @yang_i_li we discuss the genetic and molecular architecture of human traits, future opportunities and challenges and ways forward. authors.elsevier.com/a/1igrb…

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18 Jan 2024
Next week I will present at the @WesternU Bioinformatics Seminar Series! It will be over Zoom, so very easy to join. A cool moment for me as well, as Western is where my academic journey began... (go mustangs 😉)
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