Giant cell urothelial carcinoma: rare, aggressive, and still poorly understood. 🔬 Giant cells ~12× larger than background tumor cells 📊 Higher stage (T3/4, metastatic) at presentation 📉 Worse OS vs conventional UC (esp. even in T1/2 disease) #Pathology #GUPath PMID42252958

40s M with testicular swelling. Diagnosis? #PathX #PathTwitter @MGBpathology @MGHPathology

For pathology trainees, something easy to miss (and a good lesson to pay attention to the aspirate): child with staging marrow for rhabdomyosarcoma...can you spot it at low power? #hemepath

Orchidectomy, adult #GUpath #GIpath #Pathresidents #pathwtitter

Can immunotherapy make residual RCC harder to recognize? Hansen et al. highlight staging pitfalls after ICI therapy. Our @AJCPjournal editorial examines the need for updated standards in post-treatment assessment. Study: academic.oup.com/ajcp/articl… Editorial: academic.oup.com/ajcp/articl…

#PathQuiz 🔬🧬 A) Multilocular Cystic Renal Neoplasm of Low Malignant Potential B) Acquired Cystic Disease-Associated RCC C) Clear Cell Papillary Renal Cell Tumor D) Tubulocystic Renal Cell Carcinoma #Pathology #GUPath

Professor Richard Scolyer has Passed Away. abc.net.au/news/2026-06-08/p…

New article out now #AIMMhighlights ▶️ HER2 DISH closely matched FISH ▶️ Discordance mainly in borderline amplified tumors ▶️ Differences clustered near the 2.0 HER2/CEP17 cutoff ▶️ Supports DISH as a robust routine testing method

#PathQuiz 🔬🧬 A) Renal Oncocytoma B) Chromophobe Renal Cell Carcinoma C) SDH-Deficient Renal Cell Carcinoma D) Low-grade Oncocytic Tumor #Pathology #GUPath

Analysis of ASPSCR1::TFE3-rearranged renal cell carcinoma shows diverse histological patterns, with papillary structures being most common. Tumor cells often exhibit clear to eosinophilic cytoplasm, contributing to the complexity of diagnosis. bit.ly/3QBWpvk

🩺 Can AI help families better understand autopsy findings? Researchers at Stanford are using generative AI to transform complex autopsy reports into accessible, family-friendly summaries. Read the interview with Meagan Chambers 👇 ow.ly/XuY550Z6ETO #Pathology

Important Request for Information (RFI) from @NIH “Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator to Support More Researchers and Maximize Scientific Productivity and Innovation” grants.nih.gov/grants/guide/… Some suggested caps & impact:

The study found that 63% of patients with GP had high PI-RADS scores (4-5), which correlated with a higher median percentage of biopsy parts involved. This highlights the diagnostic challenges posed by GP on mpMRI. bit.ly/4omFp8Z

The correspondence from Varma et al. raises concerns about the validity of recommendations from consensus conferences. When evidence is weak or absent, expert opinions should be clearly identified to avoid misleading conclusions in clinical practice. bit.ly/4efDMVL

Can AI really replace pathologists ? Read @RunjanChetty & Dr Kenneth Fleming's take on this controversial question in this pertinent editorial piece from the JCP! bit.ly/4ds0BqN

The August 2026 issue of #HumPathol is available online! sciencedirect.com/journal/hu… #pathology #PathTwitter #PathX

With the World Cup only 3 days away, who would like to tackle this case? 🔬 Hint: a history of more than one internal malignancy. IHC shown: PAX8 #pathology #dermpath #IHCpath #MDACCPath

ASCP local chapters are the place for ASCP Members looking for new connections with pathologists and laboratory professionals! Joining an ASCP local chapter comes with a built-in community of peers who host events and discuss pressing laboratory issues. View the map above to see if any current chapter locations are near you then click here to join: bit.ly/4aoz5bK #ASCPLocalChapters

Case Report authors needed $500 honoraria #renalpath #pathtwitter #ascp @ASCP_Chicago

Have insights, experiences, or innovations to share with the digital pathology community? The Digital Pathology Association is seeking blog contributors to help educate, inspire, and advance the field of digital pathology. Whether your expertise is in clinical implementation, AI, workflow optimization, education, research, interoperability, quality assurance, or patient-focused innovation, we want to hear your perspective. Ready to contribute? Learn more about submission guidelines and submit your idea today: bit.ly/4xjQcos #DigitalPathology #Pathology #ArtificialIntelligence #HealthcareInnovation #MedicalTechnology #PatientCare #DPAv