ALT A schematic depicts the Residual Level Alignment model training approach, which yields protein residue sequence and structure encodings by aligning sequence and structure encoders in the same latent space. At the top is a seemingly random series of letters followed by an ellipsis on the left and a green protein structure on the right, each pointing below to purple and green boxes labeled “RLA sequence encoder” and “RLA structure encoder,” respectively. These boxes both point to a black coordinate below, where protein residue sequence and structure encodings are represented by purple and green sections of circular arc fanning out from the origin along the horizontal axis.

ALT Illustration of SLiMs binding to ENAH proteins