Assistant Professor at University Medical Center Utrecht

Joined September 2017
6 Photos and videos
We’re hiring! Looking for a PhD student interested in brain development and cancer to join our team at the UMC Utrecht @NeuroscienceT. An exciting collaboration with @Lena_Kutscher at the DKFZ in Heidelberg. Please reach out with questions! werkenbijumcutrecht.nl/vacat…

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Kimberly Siletti retweeted
Super proud to see our human neurodevelopmental atlas of chromatin accessibility out in nature! Thank you to @slinnarsson @MJ_Schipper @DPosthu and @ReagorCaleb, as well as the KI hospital and Cambridge University for a very joyful collaboration. nature.com/articles/s41586-0…

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Kimberly Siletti retweeted
Whole, healthy human brain data is now on the ABC Atlas! Dataset incl. 3 million cells sampled from dissections from adult donors. Samples underwent snRNA sequencing and were clustered and categorized by neurotransmitter, region, and more. ABC Atlas: portal.brain-map.org/atlases…
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Kimberly Siletti retweeted
Interested in epigenetics research? Apply for a 3-year Rurainski Postdoc Fellowship at @DKFZ! Applications close March 30th (dkfz.de/en/postdoc-program/D…).

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Kimberly Siletti retweeted
Check out our @stemcellreports paper published today doi.org/10.1016/j.stemcr.202… by @Kaneyasu1980 @shanzheng_yang @ka_wai_rine @EAsgrimsdottir et al in collaboration with @PerSvenningsson @HjerlingLeffler @slinnarsson describing how to make midbrain #Dopamine neurons from hES cells.

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At #SfN22! I'll be presenting a poster today on our transcriptomic atlas of the adult human brain. 1:00 pm, Session 031.17. Come visit!
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Kimberly Siletti retweeted
So excited that our work is on bioRxiv! BIG thanks to my colleagues from Dr. Bing Ren’s lab and @CEpigenomics. A really fun collaboration with @shangjingbo @JoeEcker, Marga Behrens, @slinnarsson, Trygve Bakken, Ed Lein and many others!
A comparative atlas of single-cell chromatin accessibility in the human brain biorxiv.org/cgi/content/shor… #biorxiv_neursci
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A super cool dataset! Exciting to see so much primate data the last couple weeks. Marmoset here from @fennamk and others, macaque from @kchiou @XingfanH and others! bit.ly/3CL0zpQ

19 Oct 2022
Excited to present our new preprint! We sequenced 2.4 million marmoset brain cell nuclei across major neocortical and subcortical structures. Here’s what we learned. biorxiv.org/content/10.1101/…
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Kimberly Siletti retweeted
21 Oct 2022
Excited to share the single-cell adult #macaque brain atlas—our contribution to a big week of #brainatlas preprints! W/ @XingfanH, @MichaelLouisPl1, @JShendure, & @SMack_Lab—we profiled 4.2M nuclei across 30 regions from females males. Here’s what we found bit.ly/3CL0zpQ
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So excited our single-cell transcriptomic survey of the adult human brain is on bioRxiv! @slinnarsson @MossiAlejandro @ka_wai_rine @ErnestArenasSWE A really fun collaboration with Rebecca Hodge, Trygve Bakken, Ed Lein and others at the @AllenInstitute doi.org/10.1101/2022.10.12.5…

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Altogether our study highlights enormous challenges ahead of the neuroscience community, as we aim to understand the unique assemblies of neurons and glia that populate each brain region.
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Links to code and data are available here: github.com/linnarsson-lab/ad…. We are also working to release a browsable version of the dataset, which we hope you will enjoy as much as we have. Feedback welcome!
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