Marry well, stay in shape, build something you own, and protect your time.

SEGMENT, ALWAYS SEGMENT Most confounding business problems have the same root cause: you haven't segmented your customers. You look at the top-line number. It's flat, or weird, or inconsistent with what your gut tells you. You poke at it and you can't figure out why. The answer is almost always that you're staring at an average that's hiding two or three very different stories. A few places this shows up: 1. When your high-level metrics look wonky or divergent, break them out by segment. A flat retention curve often hides one cohort churning out violently and another expanding aggressively. A "meh" NPS usually has one segment of fanatics and one segment of detractors cancelling each other out. The average is a lie. The segments are the truth. 2. When your product is trying to be everything to everyone, you need to tailor it per segment. If your roadmap has SMB founders, mid-market IT buyers, and Fortune 500 procurement all fighting for features in the same backlog, that's three products in a trench coat pretending to be one. Pick the segment you're actually building for, and ship accordingly. 3. When your pricing or positioning feels wrong no matter where you set it, it's because one SKU or pitch is spanning segments with wildly different needs or willingness to pay. Enterprise will pay 10x what a startup will for the exact same thing. A single price point either leaves money on the table at the top or closes the door at the bottom. Segment the packaging. Segment the price. The pattern holds every time. Whenever a business problem is hard to reason about, break the population into segments and look again. Nine times out of ten, the fog lifts. Importantly, you don't need to use standard gender or demographic segments. You can build your own! (And AI is a superpower here). One of the best segmentations in real life was done by @davidweiden at TellMe Networks in the early 2000s. TellMe was selling phone automation software into financial services: a half-billion dollar market, and they had almost no traction. David built a custom segmentation framework called Rifle, which scored every prospect on five weighted criteria. Where the customer was in their buying cycle (engage before the RFP, not after). Whether their long-distance carrier was compatible with TellMe's deployment model. Three more criteria with explicit weightings, including negative scores that disqualified prospects outright. The whole company aligned on the scoring. Sales stopped chasing bad-fit accounts. Product stopped building features for customers who would never close. Marketing stopped spraying the market. Over two years, Rifle drove $20M in ARR inside the qualified segment and took TellMe from a loss to a profit. They literally would have failed without the segmentation. . Founders: when a metric confuses you, when your product feels scattered, when your sales pitch or pricing won't land, segment. Segment, always segment.

Holy shit, this is some truly expert level analysis Made me mega bullish on Brazil 🇧🇷 “Brazil is the only large democracy in the world that is simultaneously a food superpower, a water superpower, an energy superpower, a mineral superpower, and a carbon superpower, with export routes that do not depend on any contested strait or chokepoint”

BTC is for *NTPs apparently I am an ENTP so my n=1 tracks

If you're under 53 years old, you have never once been alive while a human was farther than 250 miles from Earth. Tonight, four astronauts are heading 252,000 miles out. That's a thousand times farther than any person has gone in your lifetime. The 250-mile ceiling is where the International Space Station floats. Every astronaut since December 1972 has been stuck in that zone. Spacewalks, science experiments, cool photos from orbit, sure. But nobody left the neighborhood. The last crew to go farther was Apollo 17. December 1972. Nixon was president. The internet didn't exist. Cell phones were 11 years away. The youngest member of that crew is now 90 years old. The farthest any human has ever been from Earth is 248,655 miles. The Apollo 13 crew set that number in 1970, and they didn't mean to. Their oxygen tank blew up, and the emergency route home took them farther out than anyone before or since. Tonight's crew will break that record on purpose. And the crew itself. Victor Glover becomes the first Black astronaut to leave Earth's neighborhood. Christina Koch becomes the first woman. Jeremy Hansen, a Canadian fighter pilot, becomes the first non-American to do so. When they come home, they'll slam into the atmosphere at 25,000 mph, faster than any human has ever traveled. The Moon's south pole has ice. Water ice, sitting in craters so deep that sunlight hasn't hit them in billions of years. A 2024 NASA study found way more of it than anyone expected. You can split water into hydrogen and oxygen, which gives you rocket fuel, breathable air, and drinking water, all made on the Moon instead of hauled up from Earth. George Sowers at Colorado School of Mines calculated that Moon-made fuel could shave $12 billion off a single trip to Mars. The Moon is a gas station on the road to Mars. NASA Administrator Jared Isaacman announced last week a $20 billion plan to build a permanent base at the South Pole over the next seven years, with landings every six months. China is developing its own lunar lander and spacesuit, aiming for a crewed landing by 2030. The Artemis program has burned through $93 billion so far, and the first actual surface landing is penciled in for 2028. There's a real question of who gets there first this time around. Harrison Schmitt walked on the Moon in December 1972 as part of Apollo 17. He's 90. Asked about it this week, he sounded pretty relaxed. "Mars is attainable," he said. "We're humans. That's what we've always done."

It's time for take-off ✈️ Wingbits mainnet [TGE] launches April 22nd, 2026 The countdown starts now ⚡️️ wingbits.com/mainnet

Listen to this, perfectly explained. It’s all been a big fraud and a lie all done purposely.

Congrats to our partner @wingbits on mainnet launch World’s #1 DePIN for Aviation built alongside @GEODNET Take-off confirmed✈️

I'm looking for great founding engineers in the EU and LATAM. special callouts to 🇧🇷🇱🇺🇬🇧🇩🇪🇨🇴🇲🇽

O ouro levou mais de 3.000 anos para ir de ornamento cerimonial a moeda cunhada na Lídia. O Bitcoin fez o mesmo caminho em 16 anos. De collectible cypherpunk a reserva estratégica dos EUA. 23 nações. 194 empresas públicas. 365 milhões de holders. Adoção corporativa 2.5x em 2025. Stock-to-flow já superior ao do ouro. Publiquei a versão final do meu paper na SSRN.

🎯🎯“The people who invented refrigeration made some money, but most of the money was made by Coca-Cola, who used refrigeration to build an empire. LLMs are like as refrigeration & the Coca-Cola has yet to be built” ~Chamath Palihapitiya (@chamath)

Distribution and the human attention premium That marketing and distribution become the principal challenges of scaling content in an attention landscape awash in it seems like an obvious outcome as production costs collapse. But it has not yet emerged as a coherent theme from the chaotic scrum of competing effects of AI on social media, technology more broadly, and even society as a whole.

BREAKING: Someone quietly built the first AI assistant that runs on a $5 chip. It’s called MimiClaw and it's a full @OpenClaw style agent running on an ESP32 microcontroller without @Linux It’s built with local-first memory and privacy by default. No Linux. No Mac mini. No Raspberry Pi. No VPS. 100% Opensource. MIT License.

A Chinese hardware team just mass-democratized AI agents. They took a 430,000-line AI assistant that needs a $599 Mac Mini and 1GB of RAM — and rewrote it in Go so it runs on a $9.9 dev board with less than 10MB of memory. Boot time: from 500 seconds to 1 second. Cost: from $599 to $9.9. Memory: from 1GB to 10MB. Same features: code generation, web search, Discord/Telegram chat, memory system, scheduled tasks, security sandbox. The wildest part? They claim 95% of the new codebase was written by AI agents themselves. The humans just guided the architecture. It's an AI assistant that literally rebuilt itself to be smaller. Launched February 9th. Four days later: 7,400 GitHub stars. This is the pattern no one's talking about enough. Every AI capability that starts expensive gets commoditized within months. GPT-4 level models went open source in 6 months. Now the hardware floor for running a personal AI agent just dropped 60x in weeks. The infrastructure moat in AI isn't sustainable. The only defensible advantage is what you do with these tools — not access to them.

A Brazilian scientist worked in silence for 25 years on something medicine said was impossible: regenerating the spinal cord. Dr. Tatiana Sampaio extracted a protein from placentas that acts as "biological glue" — recreating the conditions that let embryonic neurons connect. Six patients with complete spinal cord injuries regained movement. Bruno Drummond was tetraplegic after a car accident. Two weeks after treatment, he moved his toe. Today he walks, climbs stairs, dances. Her quote when asked why she finally went public: "I no longer have the right to be conservative." 25 years. No social media. No self-promotion. Just the work. This is what real science looks like.

JUST IN: 🇮🇷 Iran suspends all VFR (visual flight rules) flights nationwide for three months.

🚨 Iran is experiencing GPS signal disruptions in parts of Tehran and across the country. Wingbits is monitoring the developments.

Essa mentalidade estoica o tornará inquebrável A declaração de férrea de Jordan Peterson, em 29 segundos: "Farei o bem. Não importa o quê. Não importa o que aconteça comigo. Rejeição absoluta da ideia de ser uma vítima. Não importa quanto sofrimento eu sofra — não importa quanto sofrimento imerecido e injusto, apesar da minha inocência — "Não perderei a fé e farei o bem." Isso é puro fogo estoico: O sofrimento é inevitável. Ser vítima é uma escolha. Sua reação à dor define você — não a dor em si. Escolha a virtude mesmo assim. Escolha a ação mesmo assim. Escolha o bem mesmo assim. Quando a vida te despedaça, o inquebrável não se quebra — ele decide o que transborda. Vídeo de 29 segundos de Peterson apresentando o código definitivo contra a vitimização 👇 Este voto estoico já ajudou pessoas a superar guerras, perdas e traições. Você já fez um compromisso semelhante consigo mesmo? Qual é a única coisa que poderia acontecer amanhã que testaria sua linha de "não importa o que aconteça" — e como você a manteria?