I got the AM. 🎄,🌆, ✝️,🏳️‍🌈, 🎶, 📈, 🏟, & 🌮. Roll Tide. (he/him). (AL-TX-OR-CA)

Joined June 2009
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Jun 12
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Jun 9
Unloved Bios that are interesting, down YTD: $GPCR, $MLYS, $XNCR, $ZURA
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Larry retweeted
the best song ever is 18 minutes long and made by a french/english indie band in 1993
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Jun 8
Great piece below from an underfollowed acct.
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Jun 5
$GMAB mentioned!
On today’s #BiotechHangout, @YaronWerber, @BrianSkorney, @SamFazeli8, & @t_lorriman will cover macro: AI is hot, biotech is not, industry response to COINS Act, #ASCO2026: $RVMD RAS/PDAC history in the making, PD1xVEGF controversy & $BNTX in #NSCLC, $PFE vs. $ONC in CDK4, SERD wars, $LLY’s in vivo CAR-T for myeloma, head & neck wars ($JNJ, $BCAX, $GMAB), $INCY in 1L DLBCL – can $GMAB’s Epkinly look better?, Grail’s cancer detection test, plus other data: $RLAY comes out well w/o showing at ASCO, $ABVX news – good or bad?, $PRAX epilepsy readout & much more: x.com/i/spaces/1dGYllDLangKX
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Larry retweeted
i keep hearing that ceding R&D to china is nbd because the IP is worldwide and we will still be able to mfg the drugs in the West. but this really side steps the obvious fact that the ability to develop your own drugs will be lost, like that isn't a problem or necessarily a consequence big pharma being demonstrably incapable of early stage R&D is basically the same experiment with the results staring us in the face. we can talk about incentive structures too, but i think the point still stands. let the best teams win in the global market place, sure, but let's not act like early stage R&D going to China is consequence free. it's a skillset and we could lose it.
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Larry retweeted
$SYRE - Amended Paragon license deal Expanded SPY003 (IL-23) field to all therapeutic areas, but dosing outside IBD has restrictions until 2028-2030.
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Larry retweeted
people aren’t celebrating this pancreatic cancer breakthrough enough. it should be international news
One of the most amazing things I’ve ever seen: a standing ovation for the full Daraxonrasib results I feel inspired and energised, to put it mildly — we have a targeted therapy for pancreatic cancer now, and nothing is undruggable anymore
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Jun 1
But biotech is different: x.com/reutersbiz/status/2061…

May 31
The biotech industry is still optimizing around assumptions inherited from the peak-globalization era: concentrated hubs, frictionless capital flows, and efficiency above all else. But efficiency gains for a system optimized for a world that no longer exists are marginal at best
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May 31
The biotech industry is still optimizing around assumptions inherited from the peak-globalization era: concentrated hubs, frictionless capital flows, and efficiency above all else. But efficiency gains for a system optimized for a world that no longer exists are marginal at best
Thanks for this @JTLonsdale — I’ve been having an exhausting argument with biotech VCs for the last week about not offshoring biotech R&D to cheaper scientific labor in China. Sort of getting nowhere 😛 I don’t know if it’s possible for tech folks to give a warning about the stupidity of Sequoia China, etc, so we don’t have to learn all this the hard way in biotech: x.com/jrkelly/status/2058368…
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May 31
The real challenge is reducing hidden tail correlation by creating more independent centers of experimentation, accelerating validation through FDA reform, and improving innovation signals through patent reform.
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May 31
The objective is not incremental improvement of a fragile system, but the construction of an antifragile one.
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May 27
A little jealous tbh.
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May 27
Bullish.
NEW: Nebraska woman hospitalized after a dog in another vehicle accidentally fired a shotgun at her.
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May 26
some photos I've taken during trips to LA over the years...California in general very awesome but LA and all-time great nighttime city an preposterously photogenic. not like I'm the first person to point this out but it really does look Like That.
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May 25
People online will straight up tell you Michael Clayton is a good movie and it's not
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May 22
David Bowie My Bloody Valentine Jane’s Addiction The xx Prince No Age Sebadoh INXS Lucinda Williams Vetiver
Replying to @johnondrasik
Interpol Muse Nine Inch Nails Depeche Mode Radiohead Ghost Editors Sigur Ros Mother Mother Tiesto
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May 19
LFG!
Massive walkouts from the new Nicolas winding refn movie at Cannes… we have never been more back
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May 18
What’s the alternative? Wait until it’s entirely too late to recover an industry like we did with semi’s?
Replying to @PearlF @damiangarde
For this reason I think if the playing field was leveled from a regulatory standpoint, it would not change the problem. The people who say we need to change things here and out-compete are well intentioned, but the laws of economics are irrefutable like the laws of gravity.
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