Jr. Group Leader and Lecturer @ETH Zürich, all about #chloroplasts #starchbiosynthesis #membraneremodeling (tweets=my opinion)
Joined May 2010
- Tweets 495
- Following 262
- Followers 330
- Likes 785
44 Photos and videos
Pinned Tweet
14 Oct 2025
Hot off the press, first PI paper 🎉. Reporting a novel protein (VIA1) involved in thylakoid membrane biogenesis. VIA1 (similar to ESCRT-II) and bind to chloroplast ESCRT-III (VIPP1). Showing a direct role of VIPP1 in thylakoid biogenesis. @CellReports
tinyurl.com/msrepdna
3
5
16
4,044
May 22
Many Congratulations @Kutub_joy da and team for this amazing work. 🥳💐
May 22
Rewriting plant genomes with AI-designed nuclease
Das et al. @iampriyaa_03 @romio_saha23 @Debasmi34051797 @SPAINASHX @sonali_panda19 @Kutub_joy
nph.onlinelibrary.wiley.com/…
ALT Panel (a) shows a sequential step of the complete workflow to check the efficiency of different POC1-editors in rice protoplast. Panel (b) explains the comparative knockout efficiency of Cas9 and POC1 in rice protoplasts through a graphical representation and agarose gel image. Panel (c) shows the comparative indel generation efficiency by using different scaffolds for guide RNA. Panel (d) graphically represents the base editing percentage by SpCas9 and POC1 based adenine base editor.
1
9
848
Mayank Sharma retweeted
May 22
Rewriting plant genomes with AI-designed nuclease
Das et al. @iampriyaa_03 @romio_saha23 @Debasmi34051797 @SPAINASHX @sonali_panda19 @Kutub_joy
nph.onlinelibrary.wiley.com/…
ALT Panel (a) shows a sequential step of the complete workflow to check the efficiency of different POC1-editors in rice protoplast. Panel (b) explains the comparative knockout efficiency of Cas9 and POC1 in rice protoplasts through a graphical representation and agarose gel image. Panel (c) shows the comparative indel generation efficiency by using different scaffolds for guide RNA. Panel (d) graphically represents the base editing percentage by SpCas9 and POC1 based adenine base editor.
10
38
21,161
Mayank Sharma retweeted
May 21
🌱Exciting Opportunity!
The Jarvis Group is recruiting a Research Assistant to study the mechanism and structure of the chloroplast-associated protein degradation (CHLORAD) system.
Term: 3 years
Application Deadline: 12 noon, 19 June 2026
Apply here: my.corehr.com/pls/uoxrecruit…
9
29
2,632
May 21
This article became a major news sensation, amusing to read, and difficult to believe.
tinyurl.com/2s4k8z2f
Some obvious flaws:
1. No negative control eye drops (e.g., heat-deactivated thylakoids).
1
3
62
May 21
4. Unclear whether it is "photosynthesis in the eye" or just delivery of some chloroplast proteins that causes access NADP production.
5. No TEM images provided where actual thylakoid is in cornea.
1
1
45
May 21
Recently, such "inserting isolated thylakoids randomly" studies have been emerging more frequently, often without much controls and analysis.
nature.com/articles/s41467-0…
pubs.acs.org/doi/10.1021/acs…
30
Mayank Sharma retweeted
May 8
Our new study characterizes the assembly of two functionally distinct chloroplast protein import complexes (TOC-P and TOC-N) in the outer membrane of plant chloroplasts.
Huge thanks to @IvanAhelLab and @SKhalidLab, for a fantastic collaboration!
biorxiv.org/content/10.1101/…
3
10
747
Mayank Sharma retweeted
Excited to share our latest preprint on bioRxiv!
Would love to hear your thoughts and feedback!
Two redundant paralogs of MAR1-BINDING FILAMENT PROTEIN affect B-type granule initiation in wheat biorxiv.org/content/10.64898…
3
5
24
965
Mayank Sharma retweeted
Apr 23
✨ Sharing #new publication! uncovering a new target for CO2-regulation in vesicle trafficking that provides a new perspective on plant responses to #climate change 🌱congratulations! @One__Fish @SakharamWaghma1 @rucha_karnik @LeverhulmeTrust @BBSRC
doi.org/10.1111/jipb.70269
3
3
150
Apr 10
1
4
405
Mar 23
A Recent one on plastid intron splicing from B. Pfister. @ETH_DBIOL
nature.com/articles/s41467-0…
2
3
142
Mayank Sharma retweeted
Feb 11
🚨 Positions available in Plant Science! Please share. We’re hiring:
1. Postdoc
2. PhD (UK applicants only)
Focus: root oxygen dynamics, developmental signalling. Come help us uncover how O2 shapes root development.
Apply-
sites.google.com/view/root-r…
#plantscijobs #AcademicJobs
27
63
6,155
Mayank Sharma retweeted
Jan 21
PhD opportunity in the newly minted RO2T Respiration Group! Please share!
Interested in root biology, oxygen dynamics, imaging & modelling? We’re recruiting a PhD student at the University of Nottingham.
Deadline 15th February.
jobs.nottingham.ac.uk/Vacanc…
22
43
3,564
Mayank Sharma retweeted
18 Dec 2025
Excited to share that as my group launches across Karolinska Institutet and the University of Helsinki, we’re recruiting postdocs and research assistants to study the nanoscale architecture of lipid flux using in-cell structural biology approaches, including cryo-ET and cryo-CLEM
6
4
12
905
Mayank Sharma retweeted
15 Dec 2025
- Thylakoid remodelling: A vital role for VIA1 rdcu.be/eUKyz
1
5
957
Mayank Sharma retweeted
31 Oct 2025
Lost in the ocean of #CRISPR_web_tools?
Check out @CRISPR_GATE — our newly launched web portal that brings everything you need for CRISPR design, editing, and analysis in one place!
#Cas #GlobalSouth
Article: academic.oup.com/bib/article…
Website: crispr-gate.daasbioinfromati…
5
45
144
11,521
Mayank Sharma retweeted
31 Oct 2025
This Halloween, we have a spooky evolutionary story for you. The brainchild of
@delaconcepcionj @dinokaryon & our fantastic collaborators is now out in
@NaturePlants
nature.com/articles/s41477-0… Here’s why I love this work — and why I think you’ll enjoy it too. 👇
4
24
50
3,339
Mayank Sharma retweeted
29 Oct 2025
Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.
For more details and to apply please see
imperial.ac.uk/jobs/search-j…
7
12
1,008