CTPO CoFounder Caladrius caladriushealth.ai/ | Founder, Director, Yajur Healthcare | yajur.ai | linktr.ee/manishsharmas

Joined May 2009
926 Photos and videos
Pinned Tweet
Be Patient. Progress Takes Time.
8
921
Manish Sharma retweeted
This is WILD! Tom Mueller. SpaceX employee #1, the man who built the engines and his 0.06% stake is now worth approximately $1.11 billion (Save this). But the number undersells the story. Mueller grew up in St. Maries, Idaho, population 2,500, the son of a logger who wanted him to follow the same path. He spent four summers cutting timber to pay his way through engineering school, then moved to California with nothing but a degree and a passion for rockets. He spent 15 years at TRW, one of the biggest aerospace companies in the world, watching his ideas get diluted inside a bureaucracy so he started building engines in his garage at night as a hobby. By early 2002 he had built the largest amateur liquid-fuel rocket engine in the world, 80 pounds, 13,000 lbs of thrust and moved it to a friend's warehouse. That's where @elonmusk found him. Fresh from selling PayPal for $1.5 billion, Musk walked into that warehouse and asked one question: "Can you build something bigger?" Mueller never fired that original engine, he took it back to his garage, where it still sits today. Instead, he joined Musk on May 1, 2002 becoming employee #1 on the SpaceX payroll. What followed was 18 years of building what became the most reliable rocket engine ever flown. The Merlin engine, designed from scratch powered Falcon 1, Falcon 9, and Dragon. The Merlin 1D holds the thrust to weight record for production rocket engines and it enabled the first ever propulsive landing of an orbital rocket booster, which is what made reusability possible, which is what made cheap access to space possible, which is what made Starlink possible, which is what made today's $2.1 trillion IPO possible. Mueller also started the early development of what became the Raptor engine, the full flow staged combustion methane engine that powers Starship, which no American aerospace company had ever successfully built before. He retired from SpaceX in November 2020 but he got bored within six months so he founded Impulse Space, building space tugs to move payloads around once they're in orbit, and planetary landers to deliver cargo to Mars. What an incredible story!
58
884
5,382
192,981
Manish Sharma retweeted
Discovery of a 14-protein biomarker that predicts lung cancer 5.6 years before it is diagnosed, even in non-smokers, and an anti-inflammatory medicine that prevents its progression. And, challenging dogma, the proteins are not coming from cancerous cells!
35
531
2,407
142,829
Manish Sharma retweeted
Jun 14
Creator of Claude Code: "100% of our pull requests at Anrtopic are run by Claude Code. 80-90% of code review too. The feature I’m using the most for my agents is /loops. I’m not prompting Claude anymore - I’m building loops" in 1-hour podcast, Boris shows his setup, which helps him build the #1 coding tool of this year. Worth more than a $500 vibe-coding course.
26
52
368
101,372
Manish Sharma retweeted
[In 2026]
25 Sep 2018
[In 2050] “artificial intelligence can code software far better than humans” That’s like saying an AI can write fiction, create art, and think better than humans. An AI that can create better software is an AI that runs the world, which makes the entire article irrelevant.
1
2
564
Manish Sharma retweeted
Jun 11
Anthropic Head of Product: “Fable 5 - is our best model for self-improving agentic systems. It can run for days on a single /goal. add /loops, dynamic workflows, dreaming and you become unstoppable.” in 11 minutes, the Anthropic team shows how to build long-running systems with Fable 5 from scratch. Worth more than a $500 agent-building course. Live from Anthropic’s latest stage in Japan. Unpublished.
36
139
1,342
303,957
Manish Sharma retweeted
Today I'm publishing a new essay, Policy on the AI Exponential. AI is progressing extremely fast—much faster than the policy process was built to handle. The essay lays out where I think the technology is now, and the action needed to close the gap: darioamodei.com/post/policy-…
1,342
2,432
13,558
6,517,164
Manish Sharma retweeted
Jun 11
"It goes against every investor's instinct to expect 100% a year revenue growth, over and over again, without eventually slowing down." "It is human nature to eventually concede a terminal value that seems reasonable. But not for elite founders." "Founders are the rare individuals who can keep up with the rapidly changing opportunity set, apply the full force of their leverage to their vantage point, and put dollars to work forever." a16z's David George on why late stage venture is all about late stage founders: a16z.news/p/late-stage-ventu…
22
60
444
68,741
Manish Sharma retweeted
Boris Cherny, creator of Claude Code: "The advantage isn't going to who codes best anymore. It's going to who delegates best." In 20 minutes the day Fable dropped, he explains what to learn now while everyone else pretends nothing has changed. Watch the full talk, then save the exact config below👇
29
56
385
109,011
Manish Sharma retweeted
For IT teams integrating HMIS with ABDM, both registrations are available via NHA's published APIs. Authenticate → create HP ID → register the facility. Full endpoint reference in the article and video below.
1
1
2
18
Manish Sharma retweeted
What they gate directly: → NHCX claims routing — requires verified HFR and HPR entries → DHIS incentive access — HFR registration is an eligibility condition → PM-JAY and CGHS empanelment — HFR ID is a mandatory input
1
1
2
23
Manish Sharma retweeted
HFR verifies facilities. HPR verifies professionals. Together they sit beneath every ABDM transaction; before a single health record moves, both registries must show a verified entry.
1
1
2
5
Manish Sharma retweeted
4,18,964 facilities. 6,79,692 healthcare professionals. Registered on HFR and HPR as of 5 August 2025. Here is what those registrations actually gate. 🧵#ABDM #CaladriusHealthAI
1
2
2
17
Manish Sharma retweeted
We’re introducing a new GitHub Certified: Agentic AI Developer (GH-600). As AI agents become part of modern development workflows, this role-based certification focuses on how developers and teams operate, supervise, and integrate agents across the SDLC. If you’re already working with tools like GitHub Copilot or exploring agent-driven workflows, we’d love your input. Learn more and get involved. msft.it/6013vRHHZ
124
571
3,690
2,129,992
Manish Sharma retweeted
For health IT teams integrating HMIS with ABDM, both registrations can be completed via APIs. 3 steps: authenticate → create HP ID → register the facility. Full endpoint reference in the article and video below.
1
3
4
33
Manish Sharma retweeted
One sequencing rule worth noting before registration begins: HPR must come before HFR. The administrator creating a facility record on HFR must already hold a valid HP ID from HPR. Attempting facility registration without one stops the process at the first step.
1
3
4
25