Wait until these guys find out about pip-tazo! As someone who solidly believes in the biological potency of the microbiome: "can alter the gut microbiome" is a laughably unserious endpoint. This is so cynical.

We did it! Absolutely thrilled to share the results of the ASPEN trial published today in @NEJM Brensocatib(10mg and 25mg vs placebo) reduced exacerbations over 52 weeks and slowed lung function decline A new treatment for bronchiectasis patients nej.md/4lBHwUr

Come learn to study the lung microbiome at ATS 2025! Meet and learn from an all-star team of experts. San Francisco, May 16th.

This man from the Middle Ages had a knife hand as a prosthetic Thread 🧵 on the Germanic man with a knife for an arm and how we know

Not even the craziest part of that language family

Tomorrow's Grand Rounds will feature Dr. Robert Dickson, MD, (@robertpdickson) of @umichmedicine, presenting “The Role of the Microbiome in Critical Illness" virtually and in-person. Join us! Details: medicine.wisc.edu/department…

Ryan Day is now 45-1 against Big Ten teams that aren't Michigan, and 1-4 against Big Ten teams that are Michigan

According to dynamical systems, psychiatric disorders can be seen as energy landscapes with peaks and valleys. OCD has deep valleys where neural activity gets stuck, while schizophrenia has shallow valleys that let neural activity roam too freely, connecting unrelated ideas.

This was the play that poisoned my charitable take on UM rebuilding. 4th down, game on the line, and we call a gimmick play giving the ball to a WR/passer who's never thrown a ball in a game and a QB/receiver who's never caught a ball in a game. Just play-calling malpractice.

I'm so incredibly proud of Jenn and her inspired work! Congrats Dr. Baker!!

Congratulations to the new Dr. Jenn Baker on her successful PhD defense today. GO BLUE!!!!

Ran into these guys in Ann Arbor!! @TallyHall @_H_II_ #HappyHalloween

My kid and his friends went as Tally Hall and ran into the _actual_ @shaneMauX! This is winning Halloween in Ann Arbor.

Here’s a timeline of my career Orange=grants submitted Green=grants funded Lessons learned? -persistence pays -scientist=professional writer -grant writing makes the science better -scientist=entrepreneur. Not every “invention” is a hit (learned this from @ABCSharkTank)

In contrast, in college football's top division, 134 teams play zero exhibition games, 12 regular season games, and compete for 102 trophies they made up themselves, not counting the conference, bowl, and playoff trophies. (2/7)

I've seen claims online that tardigrades can live for 30 years without food or water. A Nat Geo article says this, without attribution. My initial reaction was that this must be an estimate. Why would anyone wait 30 years to figure this out? But Japanese scientists actually did. In 2015 or so, researchers at the National Institute of Polar Research, in Tokyo, looked inside a freezer and found some old moss samples that had been collected from Antarctica in 1983. The moss had been stuffed into a plastic bag and then stored at -20 °C for the last 30.5 years. The researchers slowly thawed the moss and then rehydrated it. They found two living tardigrades and one tardigrade egg. At first, the animals moved really slowly, but then they moved a lot more after a few days and started eating algae. One of the tardigrades later laid eggs and reproduced. The other tardigrade died without reproducing. The egg also hatched and those offspring reproduced, too. The tardigrades seem to survive because they shut down their metabolisms and have proteins that protect their DNA from oxidative reactions over decades. So, in this case, an internet claim that sounds made up is actually true. Paper: doi.org/10.1016/j.cryobiol.2…

Wordle 1,192 1/6 🟩🟩🟩🟩🟩

My all-time favorite Game of Thrones intro.

Jennifer Baker (@jenn_bak_), PhD candidate @UMMicroImmuno, studies the relationship between acute lung injury & the microbiome in the labs of @robertpdickson and Gary Huffnagle, PhD. michmed.org/Ane5m #GoBlueScience