Clinical Reader in Affective Disorders and Psychosis Division of Psychiatry @ImperialBrains Views my own. Shanti.
Joined February 2009
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25 Dec 2025
Thanks Tommy- these two are becoming the Lennon and McCartney of Academyc psychiatry. Merry Xmas, Ringo.
23 Dec 2025
Love this @TheBJPsych editorial from @rob_mccutcheon @sameerjauhar @tobypill
The clinical application of neuroimaging in psychiatry feels as far away as ever, sadly
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31 Aug 2025
We are hiring! PhD w me, @rob_mccutcheon See what you think. linkedin.com/posts/sameer-ja…
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17 Aug 2025
Thank you @JAMAPsych and funders @wellcometrust @UKRI_News thread here x.com/sameerjauhar/status/19…
16 Aug 2025
#Dopamine synthesis capacity is reduced in psychosis with #depression compared to mixed/mania syndromes, while positive psychotic symptoms correlate with higher dopamine synthesis in the associative striatum. ja.ma/3HzCyZh @_ecologos
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16 Aug 2025
Wise words
16 Aug 2025
My last task: Warn field re chatbot dangers to our patients/species.
I've done 8 papers to appear during next few months.
This 1st one decribes:
1)Types of harm
2)Who's vulnerable
3)Why it happens
4)Possible fixes
Please spread the word (open access):
psychiatrictimes.com/view/pr…
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13 Aug 2025
Does Mother Nature Read the DSM? Findings from our new paper in @JAMAPsych jamanetwork.com/journals/jam…
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13 Aug 2025
Take home? The DA system appears affected in affective psychoses, particularly limbic striatum. And positive symptoms related to DSC irresspective of diagnosis. Symptoms, not diagnoses are related to DA here, though area of DA dysregulation in mood is (understandably) different.
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13 Aug 2025
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Sameer Jauhar retweeted
12 Jul 2025
Most viewed this week from @JAMAPsych:
Systematic review and meta-analysis: Stopping antidepressants leads to slight symptom increases compared to placebo, but these symptoms are not clinically significant and do not include mood changes.
ja.ma/3IGmK72
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12 Jul 2025
Dull and Hill would probably disagree with you, and their work was quite impressive. If the response to survey is less than 20%, it is very difficult to infer causality. I do not think that is
Contentious.
12 Jul 2025
There are no randomised trials showing a relationship between cigarettes smoked and lung cancer - these are based on surveys. A survey is a reasonable way to see a duration-response effect and it was strong and backed up by other studies. odd to argue against really
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12 Jul 2025
The authors found no relationship between duration of prior antidepressant treatment, as stated quite long, and discontinuation symptoms. drugs stopped abruptly. you suggested we missed this, we did not. You like the study, the findings disagree with your premise. Shanti.
12 Jul 2025
In case Dr Jauhar is unsure - there are good estimates of this from the Rosenbaum study (11 months exposure) : 66% for paroxetine and 60% for sertraline. (not a good study to look at fluoxetine) biologicalpsychiatryjournal.…
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11 Jul 2025
Summarises it better than I could.
10 Jul 2025
🧵Not Everything Is Withdrawal 🚨1/9
When ideology overshadows science, patients suffer.
A new systematic review in JAMA Psychiatry just released.
Let’s talk about what it shows-
and why the current withdrawal ONLY narrative risks harming patients. 1/9👇
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11 Jul 2025
I do not think this gentleman has read the paper, as there are a few studies that were longer than eight weeks included in the paper. Shanti.
11 Jul 2025
🧵My response in the New York Times: “If you are looking at people on the drugs for eight weeks, you are not going to find withdrawal,” said James Davies... “It’s like saying cocaine isn’t addictive because we did a study on people who had only been taking it for eight weeks."👇
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Sameer Jauhar retweeted
10 Jul 2025
Antidepressant withdrawal symptoms may be less common than previously thought, a 'gold standard' data review has found.
@ImperialBrains, @KingsCollegeLon and @UCL researchers reviewed 50 studies with more than 17,000 participants 🔽
imperial.ac.uk/news/266013/r…
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10 Jul 2025
Fairpoint. Though please see this paper, cited in our review. You may know the author. He used this cut off.
He just retweeted this, @markhoro
10 Jul 2025
The fact the review is interpreted as ‘reassuring’ by its authors is concerning, and suggests future patients may not be properly informed about the risks of antidepressants 5/n
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