New preprint! We used simulation-based inference to predict compensatory potential of parameters given different causes of hyperexcitability. Check it out and drop me an email if you have questions/comments. biorxiv.org/content/10.1101/…

How can we train biophysical neuron models on data or tasks? We built Jaxley, a differentiable, GPU-based biophysics simulator, which makes this possible even when models have thousands of parameters! Led by @deismic_, collab with @CellTypist @ppjgoncalves biorxiv.org/content/10.1101/…

The lab's first paper, "Probing multiplexed basal dendritic computations using two-photon 3D holographic uncaging," is now online at CellReports (cell.com/cell-reports/fullte…). Congrats to @ShulanX and @Somit_sam on an outstanding and exquisite effort 👏. @PurdueBME @Research_Purdue

Our @eLife paper on artefactual Ca2 waves following calcium indicator expression is highlighted in neuroscience magazine @_TheTransmitter. Really nice talking with @avaskham and seeing the perspectives from @Sheffield_Lab, @DanielDombeck & @LoogerL thetransmitter.org/methods/w…

"Angels of Victory" Moschun, a town just northwest of Kyiv. The local community established an improvised memorial site in this location of old dugouts and trenches from 2022. During the Battle of Kyiv, Moschun was the only place where elite Russian forces managed to cross the Irpin River and consolidate a small bridgehead. Their continued advance through Moschun would mean essentially entering Puscha Vodytsya (a recreational suburb in the woods) and then Kyiv's northwestern districts along the city beltway. Yet... Ukrainian forces, mainly the 72nd Mechanized, in an act of valor and heroism, managed to keep Russians off in a terribly hard battle and eventually knocked the enemy out of the town by March 21. This is where the Battle of Kyiv, and with it the modern history of Europe, was essentially resolved. Kyiv was saved here, and so many paid with their lives for this. When you come to our country, don't hesitate to come over and pay respects to the guys who became angels in these dugouts in the woods.

Ukraine cannot fight evil with empty hands on.ft.com/440DFYV

Our newest preprint ist out. First one from my time in Japan. About inhibitory connections between parvalbumin interneurons and synchronous oscillatory network states. biorxiv.org/content/10.1101/…

I love this cover so much! @Norambr did such an amazing job (both in designing it and in supporting me throughout my PhD project journey). So please enjoy these cute mice exploring the path connecting the medial septum circuit to the VTA 🐭

A septal-ventral tegmental area circuit drives exploratory behavior My PhD work has been published in @NeuroCellPress and I couldn’t be happier! A thread 🧵(1/n) sciencedirect.com/science/ar…

When I was a kid, I was a very optimistic one. Always interested in military history, I read many books and articles about WW2 and wondered at the insane casualties of that war. I used to think these meat assaults would be impossible now, in the 21st century, with its internet, technology, and value of human life. But they came back in the most insane way imaginable. In Full HD, 24 hours a day, in the palms of my hands.

Really happy to announce that the editorial we wrote with @TTchumatchenko and Jeanette Hellgren Kotaleski is out! The special issue on computational neuroscience they edited is full of incredibly interesting contributions (all open access!). Link here: tinyurl.com/y29epzwv

Great summary here from @_Silver_Black_ of his #NeurIPS2023 paper - if you're in comp neuro and use gradient descent to train networks with separate E and I units, this will be really useful to you! (PS - This was from @_Silver_Black_ 's undergrad project in the lab!)

Must-read thread on the supposed "slow-down" in EV sales, which is really shorthand for "not actually slowing down, but incumbent car manufacturers being out-competed by new entrants".

COUNTRY ANALYSIS: #Japan's GX #decarbonisation strategy fails to put #renewables at its core; its focus on "clean coal" tech at home & overseas inconsistent w 1.5˚C pathways. Without a rapid #coal phase-out, Japan will be seen as a laggard. "Insufficient" bit.ly/CAT_JPN

I just saw Ukrainian air defense working against Russian. It sounds like fireworks. It is the second night of attacks. Yesterday, about 66 drones were intercepted over Kyiv. The night is just starting. Let’s see how it goes. (pics are from Reuters) 1/

⚡️Russia launches record number of drones into Ukraine on eve of Holodomor Memorial Day. Russia launched a record number of drones into Ukraine over the course of six hours on the eve of Holodomor Memorial Day on Nov. 25.

preprint Alert📢 Time to talk about the🐘 in the room of genetically encoded Calcium indicators (GECIs). These indicators are widely used to report activity in the brain and an invaluable tool, but the expression of these GECIs can change activity. 🧵1/7 biorxiv.org/cgi/content/shor…