Are all skin TRM cells created equal? Beyond excited to share our new paper in @ScienceMagazine, where we show diverse CD8 TRM use distinct molecular pathways to develop and persist in skin, which we can target to fine-tune the skin-immune landscape🧵👇🏻 science.org/doi/10.1126/scie…
Excited to share my graduate work from the @EJohnWherry lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @SciImmuno. Main findings below!
science.org/doi/10.1126/scii…
Very happy to share this new work on LAG3 and PD1. Has been a long road to (begin to) sort out how LAG3 functions in CD8 T cell exhaustion. Great work by Shin Ngiow and super collaboration (and 2 other great papers) with @Vignali_Lab and Dario Vignali cell.com/cell/abstract/S0092…
and also excited today to see @divijmathew paper from the lab online now in @ScienceMagazine , a mammoth effort exploring how JAK inhibition modulates checkpoint immunotherapy responses! congratulations Divij!!! science.org/doi/10.1126/scie…
so excited to see this story from the amazing @ScientistBecs and @SunLab_Official out this week! super cool data on how dietary restriction can modulate NK cell function and cancer immunity, massive congratulations to my 🇦🇺 sci-sister Bec! 🙌💫🍾 you are awesome!
Thrilled to have this story out online @ImmunityCP!! Together with @SunLab_Official, we highlight how dietary fasting improves NK cell anti-tumor immunity and examine the tissue-specific processes that drive these improved responses 🧵cell.com/immunity/fulltext/S…
📣New podcast episode has dropped! 'Autoimmune skin conditions could be treated by targeting T cells' with @simpak
🎧Find us wherever you listen to your podcasts or via our website: doherty.edu.au/news-events/p…
@UniMelbMDHS @TheRMH@LMackayLab
Melbourne researchers have made breakthrough discoveries that may help those suffering from skin conditions such as psoriasis. They found new molecules that control disease-causing immune cells in the skin and can be targeted without impacting the barrier that fights off cancer. To discuss, @Rebecca7Maddern spoke with Dr @susanna_c_ from @TheDohertyInst. 7NEWS.com.au#7NEWS
Are all skin TRM cells created equal? Beyond excited to share our new paper in @ScienceMagazine, where we show diverse CD8 TRM use distinct molecular pathways to develop and persist in skin, which we can target to fine-tune the skin-immune landscape🧵👇🏻 science.org/doi/10.1126/scie…
Top of the list on my thank-you's is the one and only brilliant @susanna_c_- not everyone gets to experience the happiness of sharing a co-first author paper with their best friend, and I feel incredibly lucky to do it with you 🌟🌟
And last but not least: to @LMackayLab herself -- for pitching me this project when I was bored of measuring tumors, all your support, and for taking this science all the way to the finish line with me. We finally made it! 💫🏆