Incoming Assistant Professor at CUAnschutz in Jan 2025 | Post doctoral fellow in the Shih lab at SCRI | Brain perivascular cells in small vessel disease
Joined May 2019
- Tweets 41
- Following 286
- Followers 238
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Pinned Tweet
13 Jun 2024
I am thrilled to share that the Bonney Lab will be opening its doors come January @CUAnschutz in the department of Anesthesiology! We will study perivascular pathology in cerebral small vessel disease using in vivo and ultrastructural imaging approaches.
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Stephanie Bonney retweeted
6 Oct 2024
Excited to share that we have a new preprint online!! 🙌 #microglia #liveimaging #neonatal #aging
biorxiv.org/content/10.1101/…
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Stephanie Bonney retweeted
18 Sep 2024
Super excited to share our work: inhibiting Ca2 channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia. nature.com/articles/s41593-0… 1/6
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Stephanie Bonney retweeted
11 Sep 2024
1/4 We are thrilled to announce that our 🌍 collaboration has resulted in a paper in @_JCBFM. @Gazz4_Science @CathFoster_ @BradASutherland @UTAS_ @SeattleChildrens @uni_copenhagen
doi.org/10.1177/0271678X2412…
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7 Sep 2024
Ever wonder if small injuries to capillaries have lasting consequences? Our work exploring this question is now out! None of this would have been possible without the help of some brilliant minds - @NielsonCara @sosamariaj @OrlaBonBon @AndyShih_Lab pnas.org/doi/10.1073/pnas.23…
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7 Sep 2024
We found that the vasomotor dynamics of upstream transition vessels is greatly attenuated however mural cell calcium signaling is maintained. Consequently, chronic constriction of the upstream transition vessels reduced blood flow to uninjured secondary off-shoot capillaries.
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7 Sep 2024
These studies demonstrate how small injuries to capillaries could alter blood flow in a broader sense within each microvascular network unit. There are sooo many more details to these studies so if you are curious I hope you take a dive deeper into our paper.
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13 Jun 2024
I am thrilled to share that the Bonney Lab will be opening its doors come January @CUAnschutz in the department of Anesthesiology! We will study perivascular pathology in cerebral small vessel disease using in vivo and ultrastructural imaging approaches.
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13 Jun 2024
I have soooo many people to thank for all their guidance and support along the way, most of all my mentors @AndyShih_Lab and @SiegenthalerLab. And my amazing colleagues @sosamariaj and @NielsonCara for going on crazy adventures with me in the Shih Lab.
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9 Apr 2024
What a great community of researchers! Loved learning about how we are all tackling CAA, so excited to be apart of this!
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Stephanie Bonney retweeted
26 Mar 2024
Myself, @UpasanaMaheshw3 and @stephkbeee are happy to be hosting the Special Collection. You are welcome to submit!
Find more info here: frontiersin.org/research-top…
Please RT
#cerebrovascular #mentalhealth #vascularbiology #newPI
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Stephanie Bonney retweeted
17 Feb 2024
What makes cerebral white matter more vulnerable with age? In this mouse study, we show that large and rare venules are bottlenecks for blood flow in the white matter. Deep branches of these venules are constricted with age, leading to reduced blood flow.
biorxiv.org/content/10.1101/…
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27 Nov 2023
This mini review was a fun one for @sosamariaj and I where we dove into the mysteries of brain perivascular fibroblasts! Thank you to @AndyShih_Lab for guidance on this one! Please enjoy 😊!
frontiersin.org/articles/10.…
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9 Nov 2023
Happy to share the latest preprint from the @AndyShih_Lab! Here we learned how focal capillary injury in the brain may broadly affect blood flow. These adventures wouldn’t have been possible without @NielsonCara and @sosamariaj by my side! biorxiv.org/content/10.1101/…
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27 Jul 2023
Happy to share that my K99 is getting funded! I will be diving deeper into the mysteries of perivascular fibroblasts in the brain🕵🏻♀️! None of this would be possible without the support from my amazing mentors throughout this journey @AndyShih_Lab @SiegenthalerLab!
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27 Jul 2023
I also have to give a big shout out to @sosamariaj for being such a great partner in these explorations!
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Stephanie Bonney retweeted
12 May 2023
Does perinatal intermittent hypoxia affect cerebrovascular network development?
Unfortunately, we don’t have the answer yet but we have a hypothesis! @AndyShih_Lab
#neonatal #braininjury #cerebrovascular #intermittenthypoxia
Check the preview 👇
karger.com/dne/article/doi/1…
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4 May 2023
The MICrONS 3D EM strikes again! This time we were curious about endothelial features that may dictate vessel size. Check it out if you’re curious too!
Shout out to @sheridan_sarge for quite the feat during her rotation!
3 May 2023
Brain capillary diameters are fine-tuned to optimize blood flow and nutrient delivery. #Pericytes can regulate capillary size, but is that the whole story? Here, we use #MICrONS volume EM data to show that endothelial structure is also involved.
biorxiv.org/content/10.1101/…
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Stephanie Bonney retweeted
27 Apr 2023
In this review, we discuss exciting advances in deep imaging that can enhance our understanding of white matter degeneration in mouse models of #AlzheimersDisease and #dementia.
ahajournals.org/doi/10.1161/…
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