So much fun recording the @IJROBP podcast today with @HenningWillers and @sueyom at the helm! So excited they wanted to talk about biology (#RadBio4life🧬) and truly honored that they selected our work. Get ready for "CIN City" to hit your podcasts next month!

Karl Popper’s, ‘Open Society and Its Enemies’ remains one of the most compelling defences of open discourse as a civilisational mechanism of error correction. For Popper, Truth is never possessed in its entirety. It can only be understood through a logical process of criticism, disagreement, and the continual testing of ideas. A society that is capable of correcting its mistakes entirely depends upon the freedom to question prevailing assumptions and to expose falsehood through reasoned debate. It is therefore entirely regrettable that one of the more insidious realities of our age is that certain individuals and institutions invoke the language of the open society while inverting its essential principles. Under the banner of tolerance, safety, equity or consensus, group-think, they have deliberately narrowed the range of permissible inquiry and badly damaged the very processes through which truth is discovered. Popper understood that certainty is the enemy of progress. Indeed, a civilisation that loses its capacity for honest discourse loses its principal means of self-correction. Once criticism is treated as heresy and dissent as a threat rather than a necessity, the foundations of the open society begin to crumble from within. beg you to read Popper. To read @DavidDeutschOxf. To listen to and absorb the work of @ToKTeacher @naval @ConjectureInst and the many other great critical rationalists. We ought to understand the great peril we face.

Discovery of a 14-protein biomarker that predicts lung cancer 5.6 years before it is diagnosed, even in non-smokers, and an anti-inflammatory medicine that prevents its progression. And, challenging dogma, the proteins are not coming from cancerous cells!

1) Why do immune-excluded tumors resist immunotherapy? T cells are there—but they can't effectively infiltrate the tumor. pubmed.ncbi.nlm.nih.gov/4199… #RACIN tested whether #LDRT (1 Gy) could reprogram the #TME and unlock anti-tumor immunity. @DangajD

1/5 An open letter to @TheLancet from an Iranian-Jewish cardiologist. Today, one of the world's most prestigious medical journals published a campaign to suspend the Israeli Medical Association from the World Medical Association — the body founded after WWII to ensure physicians would never again be weaponized by political ideology. I'm a cardiologist. I'm an Iranian Jew who grew up under a regime where medicine was subjugated to the state. What The Lancet just did is a disgrace to my profession. Here's what they published — and what they deliberately left out.

“My confidence comes from my work ethic.” @jalenbrunson1 @nyknicks #NBAFinals

2016 NCAA Champions. 2026 NBA Champions.

Congrats to the Brunsons, @nyknicks and their families, fans on a well deserved championship! 🎉

💭We treated the cancer. Now what? 📊 Long-term follow-up of 782 men ≤59 years treated with LDR brachytherapy demonstrated outstanding oncologic outcomes: ✅ 15-year biochemical failure: 4.9% ✅ 15-year prostate cancer-specific mortality: 1.8% Yet of the 114 deaths observed, only 14 (12%) were due to prostate cancer. ❤️ Cardiovascular disease (32%) and 🎗️ other malignancies (30%) accounted for most deaths. Notably, 🍬diabetes nearly doubled the risk of death, while current smokers🚬 had ~3x higher mortality than non-smokers. As prostate cancer outcomes improve⬆️, survivorship, cardiovascular health🫀, smoking cessation🚭, and management of comorbidities may be just as important as cancer control itself. advancesradonc.org/article/S… @ASTRO_org

Researchers increasingly believe the 40s, 50s and 60s represent a critical window for protecting cognitive health later in life, suggesting dementia is driven by years of metabolic stress, inflammation and vascular damage accumulating across the body. wapo.st/4ehdfaz

General Keane is wrong on this one. Hezbollah should in no way, shape of form, be included in a "deal" with Iran. Lebanon is, or rather is trying to be, a sovereign state. Including it in the "deal" is legitimizing Iran's hold on Lebanon. This is not in the interest of the US.

BREAKING: A Toronto police officer has been murdered after executing a search warrant on an Iran-back Hezbollah Kta’ib cell in Canada.

2 years later and we still get chills @TomBrady 🗣️

New in #practicalRO: Clinical Heterogeneity and Risk Stratification of Carotid Blowout Syndrome After Definitive Radiation Therapy for Nasopharyngeal Carcinoma. tinyurl.com/proqytan

"Never be afraid to fail... You put the confidence you have in everything you do when the lights are on because of everything you've done when no one is watching." Jalen Brunson on the mindset it takes to play and win at the highest level. Game 5: Saturday, 8:30pm/et, ABC

For medical information, general AI frontier models (Google, OpenAI, Anthropic) outperformed specialized @EvidenceOpen and @UpToDate as assessed by 12 US clinicians, randomized and blinded to which model and extensive testing/benchmarks. This was not anticipated. @NatureMedicine nature.com/articles/s41591-0…

That's our member behind the wheel. He was pulled out of the cab and suffered shock and physical injury to his arm, back and head. The whole city is elated about our hometown team — and that includes drivers who watched the game last night at airport lots while waiting for the next fare, listened on their radios while cruising for the next job, and huddled at hotel lines with the same heart-stopping anxiety that turned into the most beautiful joy. Pulling the cab driver out of his seat, stomping on and shattering his hood turned our joy into a nightmare. When you see the yellow, do you not see the person behind the wheel? That's someone's spouse, child, parent or friend — a New Yorker. He wasn’t out there for a joy ride, he was working to make ends meet and to get his fellow New Yorkers home safely. Cabbies pay just to go to work. They pay for their cars — whether through loans or leases. Drivers need safety on the job, both in the quiet moments of ordinary days and in the middle of public celebration. Shame on anyone who turns these joyful moments into nightmares for fellow New Yorkers.

Radiotherapy still has a very strong track record here. While ablative techniques are getting lots of attention, moderate-dose RT delivers excellent local control for progressive or symptomatic desmoids in the vast majority of cases. 4/8

The U.N. Office of the High Commissioner for Human Rights says Hamas beat, maimed and publicly executed Palestinians during its war with Israel in acts amounting to war crimes. If the UN can admit it, it must be real, real. apnews.com/article/hamas-exe…

Tech must reorient towards moral purpose for it—and humankind—to flourish, argues Glen Weyl economist.com/by-invitation/…