@syssig.bsky.social mtDNA, nets, noise, inference | @IX_AI_SciCentre @ImperialX_AI @ImperialMaths
Joined October 2020
- Tweets 134
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Pinned Tweet
14 Dec 2020
Systems and signals group at @ImperialMaths led by Nick Jones. Stay tuned for our latest research on #mitochondria #aging #genetics #biomathematics #physicalbiology #networks and #ML.
We blog regularly systems-signals.blogspot.com and there's more info at imperial.ac.uk/people/nick.j…
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7 Mar 2025
Our paper 'Cryptic mitochondrial DNA mutations coincide with mid-late life and are pathophysiologically informative in single cells across tissues and species' nature.com/articles/s41467-0… now out in Nature Communications. See our thread on bsky
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29 Nov 2024
We will begin the switch over to other social media and have a blueskye account @syssig.bsky.social
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31 Jul 2024
We decided to readvertise our exciting paper 'Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologically informative in single cells across tissues and species' 1/6 biorxiv.org/content/10.1101/…
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31 Jul 2024
Over 7 datasets, in multiple tissues in humans, mice and rats, cells with cryptic mtDNA mutations have gene expression changes consonant with ageing including immune effects and protein misfolding. We give experimental corroboration in human cell lines. 5/6
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31 Jul 2024
Calorie restriction (CR) is known to improve healthy ageing and we find indications that CR rats have lowered levels of cryptic mtDNA mutations. CR can increase mtDNA numbers and our theory predicts that higher mtDNA copy-numbers slow accumulation of mtDNA mutations. 6/6
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Systems and Signals retweeted
23 Jul 2024
🌟 Six 4-year Independent Fellowships dedicated to AI in Science in a program supported by Schmidt Sciences and Imperial College London (offered through @imperialcollege Research Fellowships).
🗓 Deadline: 19 August
🔗 Read about the fellowships ➡ imperial.ac.uk/news/255057/i…
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Systems and Signals retweeted
23 Jul 2024
🌟 Ten 2-year Independent Fellowships dedicated to AI in Science in a program supported by @schmidtsciences:
➡ Eight 2-year Eric and Wendy Schmidt AI in Science Postdoctoral Fellowships.
➡ Two 2-year Chapman Schmidt Fellowships.
🗓 Deadline: 20 September
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Systems and Signals retweeted
23 Jul 2024
📢 Job Alert: 16 Independent Fellowships in AI in Science!
The @IX_AI_SciCentre seeks 16 new fellows to join their prestigious programme and accelerate artificial intelligence research in Engineering, Natural and Mathematical Sciences.
How to apply: imperial.ac.uk/ix-ai-in-scie…
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8 Nov 2023
Please circulate: new I-X lectureship in I-X and Imperial Statistics: imperial.ac.uk/jobs/descript… @ImperialX_AI learn about I-X here ix.imperial.ac.uk/
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Systems and Signals retweeted
25 Sep 2023
Work by @olivercliff @AnnieGBryant @NaoTsuchiya @jlizier published today in @NatComputSci !
Article link: nature.com/articles/s43588-0…
And thanks to @jkbren for a really clear and thoughtful commentary: nature.com/articles/s43588-0…
31 Jan 2022
New preprint! @olivercliff w/ @NaoTsuchiya @jlizier: "Unifying Pairwise Interactions in Complex Dynamics". Want to quantify the relationship between two time series? We compared over 249 pairwise dependence measures on >1000 multivariate time series 😮
arxiv.org/abs/2201.11941
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7 Nov 2023
Work by @FerdinandoInsa1 on boosters for COVID19 versus Delta/Omicron, with great @UKHSA collaborators. journalofinfection.com/artic… Boosters work, but protection wanes in ~4 months highlighting the need for continuous monitoring of vulnerable people and for correlates of protection.
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Systems and Signals retweeted
6 Oct 2023
📌JOB VACANCY: Senior Teaching Fellow
We are looking for a Senior Teaching Fellow who will have a key role in the training of the @IX_AI_SciCentre Fellows and developing our educational programmes within I-X.
Deadline: 26 Oct
Apply below⬇️
imperial.ac.uk/jobs/descript…
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Systems and Signals retweeted
7 Aug 2023
📢11 new independent Fellowships in #AI in #science are now open for applications👏
Don't miss out on this fantastic opportunity to be at the forefront of @imperialcollege #AIresearch 🤖
⬇️Find out more & apply
imperial.ac.uk/ix-ai-in-scie…
@ImperialAI @ImperialDSI @ImperialSci
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Systems and Signals retweeted
12 Jul 2023
Coming Soon...
Launching in August, there will be a further round of up to 8 two-year #AI in Science #fellowships.
These are flexible & independent and you will be joining a cohort of top scholars based in @ImperialX_AI!
Keep an eye out here ⬇️
ix.imperial.ac.uk/research-c…
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Systems and Signals retweeted
12 Jul 2023
Applications are now open for 3 independent 4-year fellowships dedicated to #AI in Science & supported by @SchmidtFutures
Based in @ImperialX_AI, these prestigious Imperial College Research Fellows will be given bespoke training & 121 career development
imperial.ac.uk/jobs/descript…
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9 May 2023
An exciting AI in Science themed independent fellowship for two years joint between the African Institute of Mathematical Sciences in Kigali and Imperial. @ImperialX_AI @AIMS_Rwanda
5 May 2023
📢Don't miss out on the AI in Science Postdoctoral Fellowship between London & Kigali: based at @imperialcollege in I-X for the first year & @QL_Africa, @AIMS_Rwanda for the second.
Support from @SchmidtFutures & @CarnegieCorp
Deadline: 31 May
@AIMS_Next
imperial.ac.uk/jobs/descript…
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