For readers interested in cancer immunotherapy, this article reviews the clinical landscape for agonistic antibodies as immunotherapies and discusses how mechanistic insights should broaden their clinical application nature.com/articles/s41573-0… rdcu.be/flSve #ASCO26

For readers interested in bispecific antibodies in oncology, here's a review #ASCO26 nature.com/articles/s41573-0… rdcu.be/flJDG

To boldly go where no drug has gone before - great news to finally have the ADC revolution reaching #sarcoma. Amazing introduction to the session by @VivekSubbiah #ASCO26 @PTarantinoMD @NassifElise @APConley77

In 1997, Brazilian soccer player Roberto Carlos took a free kick from 35 meters against France that seemed to defy the laws of physics as it curved around a wall of defenders at an angle that seemed impossible. ⁠ ⁠ This “miracle goal” led a team of French physicists to publish a study in the journal New Journal of Physics, in which they explained that the extreme spin and speed created a “spinning spiral of the ball” that overcame gravity and air resistance.⁠

1/ Thrilled to share our new paper, out today in @ScienceMagazine! We built a pan-cancer spatial atlas of tertiary lymphoid structures (TLSs) and developed computation and AI frameworks to study TLS biology at scale. science.org/doi/10.1126/scie…

The #ASCO26 Annual Meeting kicks off tomorrow. Our experts will share pioneering research and join peers to discuss the latest in cancer care. Explore presentation highlights, connect with us at our booth, and learn about career opportunities. MDAnderson.org/ASCO #EndCancer

@Cogentbio Announces @FDA Acceptance of New Drug Application (NDA) with Priority Review for Bezuclastinib in Combination with Sunitinib for Patients with #GIST @sylvestercancer globenewswire.com/news-relea…

New @nature. Discovery of a new subtype of blood stem cells—HSC-iM—which have memory to previous inflammation, such as with Covid or aging, and prognostic significance nature.com/articles/s41586-0…

Cancer type-specific variation in patterns of driver alterations across 50,000 tumors dlvr.it/TSWtCg

Caffeine content of various beverages: aim for 200-400mg/day, if tolerated, for the greatest health benefits.

🚨 Excited to announce that @MDAndersonNews is opening a 1-year #Sarcoma #Fellowship 🌎 Opportunity to train with world-renowed experts 👇 Details below on the application #leusm #medtwitter @NassifElise @NeetaSomaiahMD @APConley77

🎉 excited to announce that applications are now open for our 1-year Sarcoma Fellowship starting 07/01/26 at @MDAndersonNews 📅 Apply by 03/10/26 🧬 Advanced training 🤝 Multidisciplinary expertise 🚀 Launch your sarcoma career 🌟 Join us in improving care and advancing research

The time of day for cancer immunotherapy is associated with major outcomes. Early is better. Results from a randomized trial of lung cancer, backs up the importance of our circadian rhythm and immune system nature.com/articles/s41591-0…

Online Now: Lymph node colonization induces tissue remodeling via immunosuppressive fibroblast-myeloid cell niches supporting metastatic tolerance dlvr.it/TQflcw

The Immune Response

Congrats on your National LMS Foundation award, @priyachudasama5 #ctos2025

Proteomic profiling of >1000 FFPE samples of bone and soft tissue sarcoma revealed B7-H3 expression in all histological subtypes, with heterogeneity of expression within and between subtypes and highest expression in UPS, myxofibrosarcoma, liposarcoma, osteosarcoma #CTOS2025

🚨Historical presentation at #CTOS2025 ChonDRAgon - first positive randomised trial in chondrosarcoma 🔹Ozekibart vs placebo 🔹 mPFS 5.52 vs 2.66 months 🔹 HR 0.479; p<0.0001 🔹 a manageable safety profile - most common TRAE: fatigue, diarrhea, and nausea

Discovery of a dual culprit role that TGF-β has for suppressing the immune response in colon cancer, promoting metastasis (in experimental model) @IRBBarcelona @NatureGenet nature.com/articles/s41588-0…

Longer walks linked with less mortality and cardiovascular risk compared with short bouts of physical activity @AnnalsofIM @uk_biobank acpjournals.org/doi/10.7326/…