jacc.org/doi/10.1016/j.jacc.โฆ Confirming and quantifying what was suspected - heart failure is evolving. Significant evidence generation implications.
How does the move to PREVENT for ASCVD risk estimation affect aspirin useโ
๐jamanetwork.com/journals/jamโฆ
1โฃ >80% eligible for 1ry prevention aspirin based on a PCE risk >10% would no longer be eligible w/ PREVENT
2โฃ Most current aspirin users don't qualify under either calculator
๐๐Immensely grateful for the generous support and guidance from Dr. Ann Marie Navar, @virani_md, @ericpetersonMD, and @dramitkhera ๐๐
And many thanks to @JAMAInternalMed for offering an avenue to share our findings
Here are my takeaways for the 7 most relevant and important #ESCCongress2025 for generalists
AQUATIC, HI-PRO, RETREAT-FRAIL, DIGIT-HF, DAN-RSV were most practicing changing
POTCAST was most contentious - not as billed
Do heart transplant patients always need invasive angio to screen for graft vasculopathyโ
๐authors.elsevier.com/a/1lWfAโฆ
In this meta-analysis, CTA/PET had pretty respectable sensitivity/NPV for ruling out graft vasculopathy compared to a gold standard of invasive angiography.
๐๐Incredibly thankful to @almallahmo and Dr. Al Rifai for their supervision & guidance on this; and to my brilliant colleague @MariaAlwan_ ๐๐
And thank you to @EHJCVIEiC for allowing us to share our findings!
Our hypothesis was that an elevated amount of myocardial blood flow at rest, which PET can measure, would predict adverse event rates.
And it did, esp. in patients with a normal EF at rest.
Patients with a normal-ish EF could be further stratified as being at a *truly* low-risk of events or at intermediate risk depending on their rest flow.
In contrast, patients with a depressed EF had a uniformly high rate of events regardless.
An incredible experience at #DDW2025! Privileged to share our work on #pancreaticcancer, Fatty Pancreas, and #colorectalcancer
With 3 oral presentations, and 3 poster presentations โ
Immensely grateful for the mentorship and support of Dr. @SriGaddamMD ๐๐ผ
New genetic analysis in 200k people over 14 years
โถ๏ธapoB lp(a) best capture lipid-mediated CV risk
โถ๏ธLDL particle size adds no additional info when apoB is accounted for
academic.oup.com/eurheartj/aโฆ