Research Associate @ImperialBrains. Bioinformatics, causal inference and single-cell.
Joined November 2014
- Tweets 33
- Following 55
- Followers 41
- Likes 39
10 Photos and videos
Pinned Tweet
14 Jan 2025
Very excited to share our latest publication in @NatureGenet! Our manuscript shows how Mendelian Randomization (MR) isolates putatively causal links between cell-type specific gene expression & brain phenotypes.
nature.com/articles/s41588-0…
Tweetorial below 👇
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Alexander Haglund retweeted
27 Mar 2025
We're so thrilled to finally share with you the published version of our CUT&Tag optimization and benchmarking paper "CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks" - out in @NatureComms today: nature.com/articles/s41467-0…
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Alexander Haglund retweeted
7 Mar 2025
Just one day left to apply as computational genomics postdoc in our lab. Apply by tomorrow, 8 March:
my.corehr.com/pls/coreportal…
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Alexander Haglund retweeted
27 Feb 2025
Exciting new role for a Computational Genomics Research Associate in the lab of @sj_marzi at the UK DRI at King's!
Lead projects exploring the epigenome and transcriptome of brain cells in neurodegenerative diseases 🧠
🗓️Deadline: 08 March
Full info👉 shorturl.at/fk7jS
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Alexander Haglund retweeted
30 Jan 2025
Plasma protein and brain structural imaging evidence that #SARSCoV2 is associated with greater brain β-amyloid pathology in older adults, particularly those hospitalized or with hypertension.
nature.com/articles/s41591-0…
@NatureMedicine a matched @uk_biobank case-control study @EugenePDuff open-access
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Alexander Haglund retweeted
12 Feb 2025
📢 Our lab is looking for a bioinformatics postdoc. We have lots of exciting projects to work on, including single cell data, microglia xenotransplantations and nanopore long reads splicing analysis. Look out for the official advert next week and get in touch in the meantime 🧬🧠
ALT The Marzi Lab wearing epigenetics band t-shirts
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Alexander Haglund retweeted
30 Jan 2025
📢 CUT&Tag version 3
Sometimes the preprint to paper route can be quite the odyssey. And so in that vein, we are delighted to give you version 3 of our CUT&Tag optimization and benchmarking manuscript:
biorxiv.org/content/10.1101/…
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Alexander Haglund retweeted
26 Jan 2025
Modern GWAS can identify 1000s of hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease?
I'm excited to present our new work combining associations Perturb-seq to build interpretable causal graphs! A🧵
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Alexander Haglund retweeted
27 Jan 2025
Our new paper is finally out, showing that the same enhancer sequences - and likely the same transcription factors recruited to them - affect the activity of distal enhancers and their looping over to target gene promoters.
nature.com/articles/s41467-0…
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14 Jan 2025
Very excited to share our latest publication in @NatureGenet! Our manuscript shows how Mendelian Randomization (MR) isolates putatively causal links between cell-type specific gene expression & brain phenotypes.
nature.com/articles/s41588-0…
Tweetorial below 👇
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14 Jan 2025
13/ Big thank you to all co-authors including @VerenaZuber, @JulienBryois, @prashant1003, @AbouzeidMaya and many many more including important contributions from @DRI; @FancyNurun, @jojacksonhere and @nottalexi to name a few. Study conceived by Michael Johnson @ImperialBrains.
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14 Jan 2025
14/ What’s next? Landmark!
The Landmark project is a public-private partnership involving GSK, Novartis, Roche and UCB with the hope to find novel targets for Parkinson’s Disease, currently the fastest growing neurological condition in the world.imperial.ac.uk/news/256397/l…
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